natural killer t cells
Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis
... regulatory T cells; CD: Cluster of differentiation; CI: Confidence interval; CRP: C-reactive protein; dcSSc: Diffuse cutaneous SSc; DN: Double negative; ELISA: Enzyme-linked immunosorbent assay; ESR: ...
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Natural killer T Cells: A Powerful Via in the Regulation of Non Communicable Chronic Diseases
... The Natural Killer T cells (NKT) constitute a population of T lymphocytes that co-express an antigen receptor (TCR) and a marker of natural killer cells ...NKT ...
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Natural killer T cells contribute to the control of acute retroviral infection
... Natural killer T cells (NKT cells) are innate-like T lym- phocytes, which recognize glycolipid antigens presented by the non-classical major histocompatibility complex (MHC) ...
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Natural killer cells and natural killer T cells in Lyme arthritis
... NK cells, patients with antibiotic-responsive arthritis had higher frequencies of iNKT cells in SF than PB, but these cells were often absent in SF in patients with antibiotic-refractory ...iNKT ...
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Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells
... from 3 experiments are shown. Numbers show percentage of each gate. (E) Summary and statistical analysis for the results shown in D. The frequency of OVA-specific, IFN-γ–producing CD8 T cells is sum- ...
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Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease
... of T cells into the small intestinal epithelium is one of the earliest events in CD development ...γδ T cells are present in this infiltrate, but while αβ T cell levels return to normal ...
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The Role of Natural Killer T Cells in Cancer-A Phenotypical and Functional Approach
... NKT cells via injection with α-GalCer- pulsed-DC resulted in complete eradication of established B-16 melanoma liver metastases ...NKT cells even prevented primary tumor forma- tion in different in vivo ...
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Analysis of Invariant Natural Killer T Cells in Intra-Abdominal Sepsis
... spleens. T cells were also noted to be significantly increased in the omentum during IAS, corroborating observations made by Carlow et al [215] in a cecal ligation and puncture (CLP) model of polymicrobial ...
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Activation of human invariant natural killer T cells with a thioglycoside analogue of ? galactosylceramide
... In conclusion, we have shown that synthetic α-S-GalCer can stimulate the effector, regulatory and adjuvant activities of human iNKT cells. It is not superior to its parent compound α-GalCer in that it induces the ...
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Natural killer T cells in adipose tissue prevent insulin resistance
... iNKT cells reside not only in AT (Figure 2) but also in the liver, and both organs are critically involved in the regulation of whole-body lipid and glucose homeostasis (34), we investigated circulating lipids and ...
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Activation and regulation of B cell responses by invariant natural killer T cells
... iNKT cells can promote non- autoreactive antibody production by follicular B cells via the production of IL-17 and IL-21 ...iNKT cells and CD1d also limit autoreactive B cell activation and symptoms ...
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Exogenous Activation of Invariant Natural Killer T Cells by α Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza
... Severe influenza can lead to secondary bacterial infections with devastating consequences for human health. In view of the threat of a highly pathogenic influenza pandemic and increased antibiotic resistance, the ...
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Anti cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells
... the cells were collected and washed twice with fluorescence-activated cell sorting (FACS) buffer (PBS containing ...The cells were pre-incubated with purified anti-CD16/CD32 mAbs (BD Bioscience, Bedford, ...
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1 The Janus Face of NKT Cell Function in
... anti-inflammatory functions of different subsets of CD1d-restricted natural killer T cells during 369. Trypanosoma cruzi infection[r] ...
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Lysis of myotubes by alloreactive cytotoxic T cells and natural killer cells Relevance to myoblast transplantation
... blood cells were used as a source of NK ...NK cells was inhibited by depleting peripheral blood cells of CD16+ cells with anti-CD16 MAb and ...
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Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases
... NKT cells tends to predispose patients to more aggressive tumor growth, with NK/NKT cell number and antitumor function continuing to decline as disease progresses ...effector cells, including NK and NKT ...
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Natural killer cells control a T helper 1 response in patients with Behçet's disease
... NK2 cells from iBD patients suppress the IFNγ expression in Th1 cells, however, remains ...typical T-helper 2 cytokine that inhibits Th1 responses in vitro and in vivo [22,23], although upregulated ...
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Natural killer cells and regulatory T cells in early pregnancy loss
... cells fail to form an active immunological synapse with target ...uNK cells are cultured in vitro with or without stimuli such as IL-2, they are likely to revert back to their killing phenotype (Co et ...
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Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection
... cells were removed and 200 μl deionized water was added and incubated on ice for 10 min. After washing ten times with PBS containing 0.05% Tween-20, 100 μl biotinylated anti-IFN-g antibody was added to each well ...
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Eomesodermin and T-bet mark developmentally distinct human natural killer cells
... erythroid cells (data not ...Dead cells were excluded using Live/Dead (AmCyan, Molecular ...staining cells were fixed and permeabilized according to the manufacturer’s instructions using an ...
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