neoadjuvant therapy
New tumor regression grade for rectal cancer after neoadjuvant therapy and radical surgery
... We examined the records of 347 patients with primary mid-rectal or distal rectal cancer who had received preoperative neoadjuvant therapy followed by radical surgery at four study sites between June 2004 ...
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Neoadjuvant therapy versus upfront surgery for potentially resectable pancreatic cancer : a Markov decision analysis
... adjuvant therapy becoming the standard of care for resectable pancreatic cancer ...adjuvant therapy due to: post-opera- tive complications, early metastases nullifying the potential benefits of high-risk ...
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A Systematic Review of Neoadjuvant Therapy Compared to the “Resection First” Approach for Patients with Borderline Resectable Pancreatic Adenocarcinoma
... underwent neoadjuvant gem- citabine therapy who were initially resectable, 12% had an objective tumor response, while 27% of patients with initially unresectable disease had an objective tumor re- sponse ...
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Analysis of Presentation, Management and outcome following Neoadjuvant Therapy in Carcinoma Rectum.
... following Neoadjuvant therapy in Carcinoma Rectum” was prepared by me in the Department of Surgical Gastroenterology and Proctology, Centre of Excellence for Upper Gastrointestinal Surgery, Madras Medical ...
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Complications after oesophagectomy with possible contribution of neoadjuvant therapy including an EGFR antibody to a fatal outcome
... leading cause of death in the US causing 106.000 fatalities per year [21] although the meta-analayis has been heavily criticized by others [22]. Cullen et al., have demonstrated that voluntary reporting identifies only ...
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C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy
... Although neoadjuvant treatment is not generally recommended by urological guidelines, there is a high interest in perioperative treatment modalities such as neoadjuvant therapeutic concepts including the ...
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Predicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers
... Abstract: Neoadjuvant therapy (NAT) has been used increasingly in patients with locally advanced or early-stage breast cancer. However, the accurate evaluation and prediction of response to NAT remain the ...
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Pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a neoadjuvant therapy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
... Third, probability of overall survival was lower in the colorectal cancer patients having received neoadjuvant therapy with PIPAC before CRS and HIPEC. This obser- vation is all but a surprise since these ...
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Lymph nodes regression grade is a predictive marker for rectal cancer after neoadjuvant therapy and radical surgery
... Neoadjuvant therapy (NT) for rectal cancer (RC) reduces primary tumors and involved lymph nodes. While a prognostic value of tumor regression grade (TRG) has been identifi ed, involved lymph node regression ...
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Supporting decision-making about neoadjuvant therapy for women with breast cancer
... systemic therapy is typically given for a period of between 4 and 6 months (Kaufmann et ...following neoadjuvant therapy, rather than as a breast cancer operation followed by risk reducing surgery at ...
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Analysis of patients scheduled for neoadjuvant therapy followed by surgery for esophageal cancer, who never made it to esophagectomy
... Besides oncological reasons, there are three other causes for canceling surgery. Nine patients (1.3%) died during NT, and this was balanced between the two time cohorts. This is in line with mortality rates reported in ...
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Evaluating the response to the neoadjuvant therapy for locally advanced rectal cancers
... Materials and Methods: A total of 138 patients whose data were accessed completely were enrolled in study. According to the CRT protocol, with the radiotherapy, intravenous 5-FU 225mg/m2/g of plant (5 days per week) was ...
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Effect of neoadjuvant therapy on tumor size reduction in breast cancer
... observed. Neoadjuvant chemotherapy (NAC) has been shown to be a useful strategy in the treatment of Locally advanced breast cancer (LABC) because it results in tumor downstaging ...regimen. Neoadjuvant ...
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Upfront surgery versus neoadjuvant therapy for resectable pancreatic cancer : systematic review and Bayesian network meta-analysis
... emerging neoadjuvant approach are ...comparing neoadjuvant and surgery-first with adjuvant therapy for resectable pancreatic ...compared neoadjuvant therapy and surgery-first with ...
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Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer
... a neoadjuvant approach, may be identified at the time of post-treatment re-staging prior to surgery, and thereby be spared the morbidity and mortality of an ineffective operation, (2) neoadjuvant cXRT may ...
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Magnetic resonance imaging in locally advanced rectal cancer : quantitative evaluation of the complete response to neoadjuvant therapy
... that neoadjuvant therapy alone, in an accurately selected group of patients, represents a safe treatment associated with a good survival rate at five years (overall surviv- al 88% and disease-free 83%) ...
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Neoadjuvant therapy in early breast cancer: treatment considerations and common debates in practice
... cancer, neoadjuvant therapy is now integral to the treatment of patients with early stage ...systemic therapy given pre- or post-surgery on disease-free (DFS) and overall survival [1 e ...
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Predicting and modifying response to neoadjuvant therapy in colorectal cancer
... to neoadjuvant treatment, again there was heterogeneity between ...received neoadjuvant therapy it is possible that only chemo-resistant cells remained for sampling and ...
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GOLPH3 overexpression correlates with poor response to neoadjuvant therapy and prognosis in locally advanced rectal cancer
... A total of 148 biopsy tumor tissue samples before nCRT therapy were collected. The paraffin embedded specimens were sliced in 5 μm thickness, and GOLPH3 and mTOR expression levels were assessed by ...
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Predictors for resectability and survival in locally advanced pancreatic cancer after gemcitabine-based neoadjuvant therapy
... that neoadjuvant ther- apy could reduce the accuracy in tumor restaging [23], a possible reason for failure in exploration after neoadju- vant ...after neoadjuvant treatment, and some of these re- sectable ...
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