Nesfatin-1/NucB2
Leptin and NUCB2/Nesfatin 1 in Acute Appendicitis
... To the best of our knowledge, this study is the first to show that the levels of the anorexigenic hormones leptin and NUCB2/nesfatin-1 are higher in preoperative serum samples of patient[r] ...
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NUCB2/Nesfatin-1 in the Blood and Follicular Fluid in Patients with Polycystic Ovary Syndrome and Poor Ovarian Response
... ducted with 40 patients admitted at the IVF cen- ter, Firat University Hospital, Turkey. Twenty participants were diagnosed with PCOS according to the Rotterdam criteria (Who completed 2 of them; oligo/anovulation, ...
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Association of the polymorphism in NUCB2 gene and the risk of type 2 diabetes
... [9]. Nesfatin-1/NUCB2 plays a key role in the reg- ulation of glucose ...metabolism. Nesfatin-1 stimulated glucose-induced insulin secretion from mouse islets and MIN6 cells in a ...
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Original Article Nucleobindin 2 (NUCB2) in renal cell carcinoma: a novel factor associated with tumor development
... of NUCB2/nesfatin-1 regulates the glucose and fatty acid metabolism and improves the insulin resistance [2, ...3]. NUCB2 is expressed in vari- ous human organs and tissues, including stom- ach ...
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The Association of Nucleobindin 2 Gene (NUCB2) Variants with Type 2 Diabetes Mellitus Among Iranian Azeri-Turkish Population
... hypothalamus. NUCB2 gene expression positively correlates with insulin secretory capacity, as well as with insulin and glucagon gene expression in human ...the NUCB2 gene promoter influence the ...
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The potential role of the novel hypothalamic neuropeptides nesfatin 1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa
... of nesfatin-1 dose dependently shortened the time spent on the open arms of the EPM that is a reflection of its anxiogenic activity, increased the time spent freezing but decreased the food intake under an ...
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The Level of Nesfatin-1 in a Mouse Gastric Cancer Model and Its Role in Gastric Cancer Comorbid with Depression
... of Nesfatin-1 in gastric cancer, whereas it increases ...on Nesfatin-1 by the amount of fat ...that NUCB2/ Nesfatin-1 can promote colon cancer cell migration, invasion, ...
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Prognostication of prostate cancer based on NUCB2 protein assessment: NUCB2 in prostate cancer
... The NUCB2 protein contains a 24- amino acid putative signal peptide sequence followed by a 396-amino acid sequence, with very high amino acid sequence homology among rat, mouse, and human spe- cies (> 85%) ...
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Effects of endurance training and herb supplementation on tissue nesfatin-1/nucleobindin-2 and ghrelin mRNA expression
... [12]. Nesfatin/NUCB2 is composed of a signal N-terminal peptide of 24 amino acids, and a protein structure containing 396 amino acids ...terminal nesfatin-1, nesfatin-2 and the ...
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Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ ZEB1 pathways in colon cancer
... of nesfatin-1/Nucleobindin-2 (NUCB-2) is associated with poor outcome and promotes cell migration in breast cancer and prostate ...of NUCB2 is not well known in colon ...(TORC) 1 was involved ...
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Regulation of Feeding and Mechanisms of Intracerebroventricular Injection of Nesfatin-1 in Obese Rats
... of nesfatin-1 on high fat diet-induced DIO ...rats, nesfatin-1 inhibited feeding for a long period of ...after nesfatin-1 ...of nesfatin-1 on DIO rats lasted for 20 ...
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Plasma nesfatin 1 level is associated with severity of depression in Chinese depressive patients
... that nesfatin-1 played a role in integrat- ing feeding, glucose homeostasis, and energy expend- iture [6, ...the nesfatin-1 role in the regulation of emotional states including anxiety and ...
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<p>Changes in Serum Nesfatin-1 After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Nonalcoholic Fatty Liver Disease</p>
... of nesfatin-1 reduced plasma triglyceride and cholesterol levels in mice and signi fi cantly improved hepatic steatosis in mice fed a high- fat ...of nesfatin-1 resulted in ...
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Original Article An elevated serum level of nesfatin-1 may predict poor outcomes in patients with aneurysmal subarachnoid hemorrhages
... of nesfatin-1 in patients with aneurysmal subarachnoid hemorrhage ...October 1, 2014 to December 30, 2016 in this ...of nesfatin-1. The association between nesfatin-1 and ...
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Clinical significance of NUCB2 mRNA expression in prostate cancer
... if NUCB2 expression level is a significant predictor of BCR-free time after radical prostatectomy, Kaplan-Meier curves were plotted between high or low NUCB2 mRNA and BCR-free ...low NUCB2 mRNA ...
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Metabolic and clinical responses to Bunium Persicum (black caraway) supplementation in overweight and obese patients with type 2 diabetes: a double-blind, randomized placebo-controlled clinical trial
... by nesfatin-1 was the increase of glucose- induced insulin secretion by promoting Ca 2+ influx and L-type channels [61, ...increased nesfatin-1 levels by ...
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Nesfatin-1 and cortisol: potential novel diagnostic biomarkers in moderate and severe depressive disorder
... of each biomarker. In the present study, both nesfatin-1 and cortisol exhibited high specificity and sensitivity. In a com- bined ROC analysis using the two markers, both sensitivity and specificity reached ...
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FTX contributes to cell proliferation and migration in lung adenocarcinoma via targeting miR-335-5p/NUCB2 axis
... To explore the expression pattern of FTX in LUAD, we detected FTX expression in four LUAD cell lines (H1650, H1975, A549 and H1299). The human normal lung epi- thelial cell line (BEAS-2B) was seen as a control. As a ...
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Oxidative stress, hepcidin and nesfatin-I status in childhood iron and vitamin B12 deficiency anemias
... Three mL of venous blood was taken from the children and placed in tubes containing anticoagulant and the plasma was separated for biochemical analysis. In order to inhibit fragmentizing of nesfatin-1 ...
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... of nesfatin-1 treatment on liver tissue after common ...the nesfatin-1 treatment demonstrated a decrease of edema in the portal area, neutro- phil infiltration, and bile duct proliferation on ...
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