Neural stem cell therapy
Neural stem cell therapy for subacute and chronic ischemic stroke
... studies, stem cells must be able to navigate through the complex microenvironment of the stroke-damaged CNS in order to reach infarct tissue and maximize their therapeutic ...stromal cell–derived factor-1 ...
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A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type Inducible Gene Overexpression
... in neural stem cells and differentiated neu- rons was compared by luciferase ...in neural stem cells (without ...NSC, neural stem cell; NSE, neuron-specific enolase; RLU, ...
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Wnt5a treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice
... (DA) cell replacement therapy in Parkinson disease (PD) can be achieved using human fetal mesencephalic tissue; however, limited tissue availability has hindered further ...Embryonic stem cells ...
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Psychological Issues for Patients Undergoing Stem Cell Therapy and Regenerative Medicine
... A stem cell is a unique cell that, unlike normal body (somatic) cells, is 1) ca- pable of self-renewal over extended periods of time ( ...a stem cell over multiple cell ...
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Stem Cell Therapy for Stroke, Recent Advances, Controversies and Literature Review
... transplanted neural precursor cells after different routes of ...of cell transplantation by the 3 different routes, they found that the migration of these cells in the ischemic brain was perhaps most ...
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Potential of adult neural stem cells for cellular therapy
... different cell types of the CNS, NSCs represent a model of choice for cellular therapy in the ...adult neural progenitor and stem cells offers an alternative for cellular therapy in the ...
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Inflammatory mediators: Parallels between cancer biology and stem cell therapy
... as stem cells and cancer ...on stem cells and extrapolate on information pertaining to cancer ...Since stem cell therapy has been proposed for type II diabetes mellitus, metabolic ...
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Original Article Neural stem cell transplantation promotes behavioral recovery in a photothrombosis stroke model
... Stroke Therapy Academic Industrial Roundtable (STAIR) guidelines for the preclinical evaluation of candidate drugs ...that stem cell- based approaches may exert reparative and neuroprotective effects ...
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Clinical application of stem cell therapy in Parkinson's disease
... Fetal brain neural SC (NSC)-derived DA-ergic neurons (Figure 2) are associated with lower risk of tumor for- mation and immune rejection than ESCs [46]. Early stu- dies reported that non-differentiated NSCs taken ...
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Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
... of neural marker gene expression was carried out as described previously ...early neural markers: Pax6, Musashi1 and βIII-tubulin, and mature neural markers: MAP2 (Micro- tuble Associated Protein 2), ...
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Stem Cell Therapy: An Overview
... of neural cell of eye – photoreceptor, interneuron and retinal ganglion cell or RGS- and essential supporting cell such as retinal pigment epithelium ...distinct cell types are ...
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Ex Vivo Gene Therapy for Lysosomal Storage Disease Using Ipsc-Derived Neural Stem Cells
... transplanting neural stem cells (NSCs), the precursor cells to neurons and glia in the brain, as vehicles for the delivery of therapeutic proteins in their native ...immortalized cell lines and ...
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Stem cell therapy for the spinal cord
... particlelabeled stem cells transplanted into the central nervous system has been validated in numerous small animal studies and demon strated in several clinical trials ...labeled stem cells in vivo and ...
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Stem Cell Diversity and Applications in Therapy
... donor stem cells present in the limbus can be grafted onto the cornea following injury ...of stem cells in the treatment of corneal diseases is associated with the survival of donor stem cells, since ...
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Stem Cell Therapy for Demyelinating Disorders
... Bipotent cells isolated from the neonatal optic nerve were called O-2A progenitors, which migrate there from chiasma opticum (28). The term O-2A results from the fact, that they are able to differentiate in vitro either ...
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The bioethics of stem cell research and therapy
... human stem cell research has transitioned from controversies over the source of human embryonic stem cells to concerns about the ethical use of stem cells in basic and clinical ...embryonic ...
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PubMedCentral-PMC5436904.pdf
... cancer therapy is due to its ability to induce apoptosis in a tumor-specific ...induced cell death begins with the molecule binding as a trimer to death receptors which are present on the surface of cancer ...
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Lung cancer stem cells and low-intensity laser irradiation: a potential future therapy?
... The two types of lung cancer associated with smoking are small cell lung cancer (SCLC) and non-small cell lung can- cer (NSCLC). SCLC is characterized by very rapid tumor growth and is a more homogenous ...
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Biological Pacemakers
... have been found to express in adult heart, HCN4 being the most highly expressed one in SA node. HCN2 expression was noted in atrium, ventricle and SA node. HCN can be delivered to heart by adenoviral construct or using ...
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Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells
... underlying cell proliferation, survivals, and self- renewal cell division (Al-Hajj & Clarke 2004; Reya et ...self-renewal cell division (Luo et ...various cell types revealed that ...
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