Neural stem cells (NSCs)
Varicella-Zoster Virus Infection of Differentiated Human Neural Stem Cells
... human neural stem cells (NSCs). NSCs were induced to differentiate in culture dishes coated with poly- L -lysine and mouse laminin in the presence of fibroblast growth factor 2 (FGF-2), ...
9
Original Article Development of neural stem cells at different sites of fetus brain of different gestational age
... of neural stem cells (NSCs) in fetal brain, which may provide experimental evidence for the clinical treatment of brain injury in ...of NSCs. Results: NSCs were identified in the ...
8
Enhanced selective gene delivery to neural stem cells in vivo by an adeno associated viral variant
... Neural stem cells (NSCs) are defined by their ability to self-renew and to differentiate into mature neuronal and glial cell ...types. NSCs are the subject of intense investigation, ...
8
Original Article Intravenously delivered neural stem cells migrate into ischemic brain, differentiate and improve functional recovery after transient ischemic stroke in adult rats
... Abstract: Stem cell transplantation may provide an alternative therapy to promote functional recovery after various neurological disorders including cerebral ...of neural stem cells ...
9
The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
... endogenous neural stem cells (NSCs) mediating ...endogenous NSCs from their niches after stroke, namely from the subventricular zone (SVZ) adjacent to the lat- eral ventricles as well ...
21
Long term treatment with olanzapine increases the number of Sox2 and doublecortin expressing cells in the adult subventricular zone
... adult neural stem cells (NSCs), whichreside mainly in two canonical neurogenic brain regions - the subventricular zone (SVZ) of the lateral ventricles and the subgranular layer of the ...
10
A SY Stematic approach towards understanding stem cell biology
... various stem cell research ...how stem cells make ‘ decisions ’ during early development and how stem cells function in the ...embryonic stem cells (ESCs), induced ...
6
Original Article Valproic acid promotes neuronal differentiation and GABAergic interneuron formation in primary hippocampal stem cells
... Background: Neural stem cells (NSCs) are currently under investigation as a candidate treatment for neuronal damage and disrupted neuronal ...of cells. Whether VPA can induce the ...
8
Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution
... dividing neural stem cells (NSCs) in the developing mouse and human brain (Figure 2), controls the balance of self-renewal and neuronal differentiation in dividing NSCs through the ...
28
Regulation of Adult Neurogenesis in the Cerebral Cortex
... its neural stem cells (NSCs), which are self-renewing and can generate neurons, astrocytes and oligodendrocytes, and neural progenitor cells (NPCs), which have a tendency to ...
6
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
... We asked whether the SLPI overexpression in the spinal cord during EAE might support cell renewal in the CNS. Interestingly, SLPI induced and increased proliferation of adult NSCs, associated with the selective ...
20
Brain repair: cell therapy in stroke
... by stem cells from a variety of sources, but the potential mechanisms of action are incompletely ...mesenchymal stem cells (MSCs) and neural stem cells (NSCs) ...
14
Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy
... cord neural stem cells (NSCs) from mice expressing green fluorescent protein only in motor neurons and assessed their therapeutic effects on the phenotype of SMA ...grafted NSCs ...
16
Polycaprolactone electrospun fiber scaffold loaded with iPSCs-NSCs and ASCs as a novel tissue engineering scaffold for the treatment of spinal cord injury
... Results: The iPSCs displayed similar characteristics to embryonic stem cells and were efficiently differentiated into neural stem cells in vitro. The obtained PCL scaffolds were ~0.5 mm ...
13
Behaviors of stem cells on carbon nanotube
... Stem cells, which have the ability to self-renew and mul- tipotently differentiate into several phenotypes, have been regarded critical for groundbreaking therapy in the field of regenerative ...mesenchymal ...
6
Cell based therapy in Parkinsonism
... It is suggested that ASC-produced neurotrophic factors such as GDNF and BDNF enhance neuroprotection with an increased modulation of cell survival and a decreased modulation of inflammation, gliosis and death signaling. ...
10
Nanomaterials modulate stem cell differentiation: biological interaction and underlying mechanisms
... (SVZ) stem cells in vitro, the results have demon- strated that the RA-loaded nanoparticles can intracellu- lar release RA and promote the differentiation of stem/ progenitor cells ...SVZ ...
13
Electroacupuncture upregulates ERK signaling pathways and promotes adult hippocampal neural progenitors proliferation in a rat model of depression
... As the in vivo results showed, EA significantly increased the number of BrdU+/Sox2+ cells and the p-ERK1/2 level accompanying the amelioration of depression. However, the in-vitro-culture experiments revealed that ...
9
Adding a spatial dimension to postnatal ventricular subventricular zone neurogenesis
... of NSCs and their progeny is essential to detect changes in their numbers, proliferation or specification, which may occur following experimental ...of NSCs and their progeny, the V-SVZ is a complex ...
12
The role of hepatocyte growth factor in mesenchymal stem cell-induced recovery in spinal cord injured rats
... The post-trauma inflammatory plays a critical role during the entire period of secondary injury and was closely associ- ated with the final extent of neurological deficit [1, 8–10]. Following spinal cord injury, the ...
14