Neuroendocrine Differentiation
Solitary pulmonary metastasis from prostate cancer with neuroendocrine differentiation: a case report and review of relevant cases from the literature
... Case presentation: A 50-year-old man presented to our hospital with a chief complaint of dysuria. Histological examination revealed prostate cancer, which was classified as cT4 N0 M0, stage IV adenocarcinoma. Since the ...
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The retinoblastoma protein regulates hypoxia-inducible genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells
... outcome. Neuroendocrine prostate cancer (NEPC) is an androgen receptor-negative prostate cancer subtype that can occur sporadically but most commonly evolves from primary prostate adenocarcinoma ...induce ...
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<p>Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival</p>
... drive neuroendocrine phenotype and to maintain the survival of these ...that neuroendocrine differentiation of prostate cancer appears to be associated with a poor prognosis, it is necessary to ...
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Isolated Adenoma with Neuroendocrine Differentiation Involving Both the Facial Nerve and Parotid Gland
... of neuroendocrine tumour with simultaneous in- volvement of both the facial nerve and the deep lobe of parotid ...concerning neuroendocrine neoplasm involving the facial nerve with emphasis on clinical ...
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GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells
... Recently, neuroendocrine differentiation (NED) has been observed in a patient-derived xenograft model of prostate adenocarcinomas that developed NEPC after medical castration [14, 32, ...induce ...
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Neuroendocrine Differentiation in Breast Cancer: Clinicopathological Significance of Bcl-2 Positive Solid Papillary Carcinoma
... Copyright © 2016 Yoichiro Okubo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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Correlation of three immunohistochemically detected markers of neuroendocrine differentiation with clinical predictors of disease progression in prostate cancer
... docrine differentiation in PC is controversial, but current evidence suggests that it has an influence on prognosis related to hormone resistant tumours or a role in the con- version to a hormone resistant ...
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Original Article Prognostic significance of neuroendocrine differentiation in breast carcinoma: a meta analysis
... Multiple databases including PubMed, FreQu- est and Web of science were searched from inception to June 9, 2016 for literature retriev- al. The search terms were set as cancer OR Oncology OR tumor OR malignancy OR neo- ...
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Unusual apocrine carcinoma with neuroendocrine differentiation: a cutaneous neoplasm may be analogous to neuroendocrine carcinoma with apocrine differentiation of breast
... On the basis of gross, histopathological features and immunohistochemical phenotypes, its dermal location, the presence of infiltrating growth pattern and neural invasion, a diagnosis of cutaneous apocrine carcinoma with ...
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Case Report A rare case of adult hepatoblastoma with neuroendocrine differentiation misdiagnosed as neuroendocrine tumor
... lines differentiation, but neuroendocrine differentiation of this tumor has rare been reported in the ...with neuroendocrine differentiation of a 32-year-old woman, which was ...
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Mouse mammary tumour virus (MMTV) and human breast cancer with neuroendocrine differentiation
... with neuroendocrine features as those breast tumours with over 50% of positive synaptophysin or chromogranin cancer ...with neuroendocrine differentiation ...
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Is neuroendocrine differentiation a prognostic factor in poorly differentiated colorectal cancer?
... NED: Neuroendocrine differentiation; PDCRC: Poorly differentiated colorectal cancer; SG1: Subgroup 1; SG2: Subgroup 2; SG3: Subgroup 3; Syn: Synaptophysin; TNM: Tumor-node- metastasis; WHO: World Health ...
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Original Article Comparative analysis of colorectal mixed adenoneuroendocrine carcinoma and adenocarcinoma with neuroendocrine differentiation: a population-based study
... and ANED patients. It suggested MANEC/ANED was a malignant tumor with higher malignancy and poorer prognosis, compared with ADEC and NEC. It seemed that the NEC component in MANEC was related to poor prognosis, no mat- ...
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c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer
... Epigenetic factors play critical roles in prostate cancer (PCa) development. However, how they contribute to neuroendocrine differentiation (NED) and castration- resistant PCa (CRPC) is not fully ...
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Neuroendocrine Differentiation in the Progression of Prostate Cancer: An Update on Recent Developments
... NE differentiation in prostatic ...the neuroendocrine differentiation in PCa has increased with the identification of several neuroendo- crine factors regulating the homeostasis of prostate by ...
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Prognostic role of neuroendocrine differentiation in prostate cancer, putting together the pieces of the puzzle
... Abstract: Neuroendocrine (NE) differentiation is a common feature in prostate cancer ...NE differentiation in PC is not a stable phenotype, being stimulated by several agents including androgen ...
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<p>Clinicopathological Characteristics and Prognostic Factors of Patients with Gastric Cancer Accompanying Neuroendocrine Differentiation (NEDGC)</p>
... Results: Ages of the patients ranged from 26 to 83 years (M:F, 4.8:1). The majority of patients suffered from some symptoms (97.6%), as the most common one was abdominal pain (48.8%). Most of the tumors were ≥ 5 cm ...
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SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression
... This study sheds new light on the role of the SNAI2 gene in the pathogenesis and progression of PCa in function of the heterogeneous nature of this disease. Here we report, for the first time, that PCa is marked by the ...
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Neuroendocrine differentiation and neuroendocrine morphology as two different patterns in large cell bronchial carcinomas: outcome after complete resection
... of neuroendocrine expression by considering a fur- ther difference between large-cell bronchial carcinomas with neuroendocrine morphology only (LCCNM) as well as large-cell bronchial carcinomas showing the ...
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www.ijcep.com /IJCEP902002 Case Report Pancreatic Carcinoma with Multilineage (Acinar, Neuroendocrine, and Ductal) Differentiation
... and neuroendocrine carcinoma does not allow sufficient assessment of its biological behavior or ...and neuroendocrine differentiation may be related to a different prognosis ...
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