Neuroendocrine Tumours
Gastrointestinal and pancreatic neuroendocrine tumours and carcinomas; a review of rare tumour type
... 47. DelleFave G, Sundin A, Taal B, Ferolla P, Ramage JK, Ferone D, et al. ENETS consensus guidelines update for gastroduodenal neuroendocrine neoplasms. Neuroendocrinology 2016; 103: 119-24. 48. Harring TR, Nguyen ...
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Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours
... Non-tumoural cells within the tumour microenvironment (TME) influence tumour proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary neuroendocrine tumours (PitNETs). We aimed ...
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Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
... Well-differentiated neuroendocrine tumours (NETs) include typ- ical and atypical carcinoid ...carcinoid tumours, the uterine cervix constitutes one of the rarest locations, representing only ...These ...
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MIB-1, AgNOR AND DNA DISTRIBUTION PARAMETERS AND THEIR PROGNOSTIC VALUE IN NEUROENDOCRINE TUMOURS OF THE LUNG
... Jütting U, Gais P, Rodenacker K, Böhm J, Koch S, Präuer HW, Höfler H (1999). Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high resolution image analysis. Analyt Cell Pathol ...
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Radiation precautions for inpatient and outpatient 177Lu-DOTATATE peptide receptor radionuclide therapy of neuroendocrine tumours
... Background: 177 Lu-DOTATATE peptide receptor radionuclide therapy is administered to patients on an inpatient and outpatient basis for the treatment of well- differentiated, metastatic neuroendocrine ...
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Liver metastases of neuroendocrine tumours; early reduction of tumour load to improve life expectancy
... of neuroendocrine tumours with sen- sitivities of respectively 46%, 42%, 43% and 90% ...of neuroendocrine tumours, binding 111Indium-labelled octreotide can be used for both disease staging ...
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Epithelial to mesenchymal transition in the metastatic progression of gastroenteropancreatic neuroendocrine tumours
... Numerous studies on GEP-NETs have recently demonstrated a key role for the PI3K- AKT/mTOR pathway in tumourigenesis, particularly in pancreatic neuroendocrine tumours (P-NETs). mTOR signalling is key in ...
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Appendicular Neuroendocrine Tumours in Children: Unicentric Retrospective Study
... (2). Neuroendocrine tumours (NET) arise from endocrine and ...Appendiceal Neuroendocrine Neoplasms (NEN) (carcinoid tumors of the appendix) represent 60% of all appendicular tumors ...
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Unusual Paraneoplastic Syndrome Accompanies Neuroendocrine Tumours of the Pancreas
... of neuroendocrine tumours is di ffi cult, espe- cially if the tumour is small and ...small tumours, and published reports of prospective and retro- spective studies suggest that this technique has a ...
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Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives
... the tumours, a phenomenon not seen with regular doses of somatosta- tin analogs, but often produced by chemotherapeutic agents ...in neuroendocrine tumours, while this was not found during treatment ...
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Neuroendocrine tumours of the head and neck: anatomical, functional and molecular imaging and contemporary management
... Familial paraganglioma is associated with mutations in the succinate dehydrogenase (SDH) gene-mitochondrial complex involved in electron transfer and the Krebs cycle [44] . There are four subunits (A to D) that form the ...
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Treatment of Liver Metastases from Neuroendocrine Tumours in Relation to the Extent of Hepatic Disease
... Table 2 shows treatment of LM in relation to the three localization types. All 23 patients with type I LM underwent r0 hepatic resection. The primary tumour was resected before referral to this institution, reflecting ...
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Screening for malnutrition in patients with gastro entero pancreatic neuroendocrine tumours : a cross sectional study
... Malnutrition is an adjustable risk factor, 19 but associated with severe adverse clinical outcomes if not addressed. 1 2 Patients with GEP-NET do not typically present with major weight loss or acute illness before ...
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Patient-reported health state utilities in metastatic gastroenteropancreatic neuroendocrine tumours – an analysis based on the CLARINET study
... Utility values, especially health state utility values, are important inputs for assessing the cost effectiveness (cost utility) of new health technologies. In a cost-effectiveness model, the time patients spent in each ...
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Natural history and outcome in chinese patients with gastroenteropancreatic neuroendocrine tumours: - a 17-year retrospective analysis
... recommended for pNETs, metastatic foregut G2 NETs, and in any G3 tumours with or without liver metastases from various primary sites in the GI tract [32]. In general, well-differentiated NETs are resistant to most ...
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Multivisceral resection of pancreatic neuroendocrine tumours: a report of two cases
... Whilst further histopathological and prognostic cri- teria such as the Ki-67 proliferative index and mitotic count are included, such markers may still underesti- mate the unpredictable nature of this disease [4]. Con- ...
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Dosimetry methods and clinical applications in peptide receptor radionuclide therapy for neuroendocrine tumours: a literature review
... The included clinical articles implemented various dosimetry protocols. Most studies applied S value based dosimetry from difference sources, despite rec- ommendations to use voxel-based approaches [57, 72]. In our ...
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Quantitative analysis of phantom studies of 111In and 68Ga imaging of neuroendocrine tumours
... In the context of NETs, the first step in functional imaging came with somato- statin receptor (SSTR) scintigraphy which allowed visualization of the degree of SSTR expression in the tumours. In recent years, SSTR ...
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Horseshoe kidney and primary renal carcinoid tumour: a case report of a rare entity
... Immunohistochemical stains are utilised in the diagnosis and exclude other sites as a primary lesion. Nearly all lesions reported are positive for synaptophysin and chromogranin. Staining for vimentin and CAM 5.2 has ...
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Multiple endocrine neoplasia type 1: extensive analysis of a large database of Florentine patients
... are neuroendocrine tumours of the GEP tract (GEP-NETs), affecting about 30–70% of patients [1], usually manifest- ing as multiple adenomas and often recurrent after sur- gical ...non-functioning ...
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