neuronal cell death
A proteomic analysis of the effect of mapk pathway activation on l-glutamate-induced neuronal cell death
... induces neuronal cell death through two distinct pathways: ionotropic glutamatergic receptor-initiated excitotoxicity and non-receptor- mediated oxidative glutamate toxicity ...hippocampal ...
9
Neuronal Cell Death and Mice (Mus Musculus) Behaviour after Induced by Bee Venom
... induces cell death in human lymphocytes (Gajski & Garaj- Vrhovac ...induce cell death by inactivating p38 MAPK (Jeong et ...in cell death, such as NFAT (Nuclear Factor of ...
11
Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death
... To assess the role of autophagy in PAMAM dendrimers-induced neuronal cell death, two au- tophagy inhibitors, LY294002 and CQ, were used to inhibit PAMAM dendrimers-induced autophagy. LY294002 is an ...
15
Landshamer, Stefan (2007): Role of Bid and AIF in Glutamate-induced Neuronal Cell Death. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... mediate cell death through caspase-independent mechanisms through its serine protease activity [39, ...to death around 30 days after birth ...ischemic neuronal death ...apoptotic ...
116
Neurotrophins, immediate early genes and neuronal cell death
... l cell death is a w e ll do cum e n te d fe a tu re o f b o th ch ro n ic neurodegenerative disorders such as H u n tin g to n 's disease as w ell as several acute, and re la tiv e ly non-specific, n e u ro ...
200
Molecular Factors of Seizures Induced Neuronal Cell Death in Epilepsy and Potential Possibility for Neuroprotective Therapy
... physiological cell death, which occurs during development, normal tissue homeostasis or as a result of different cellular ...to neuronal loss and neuronal cell death. The ...
6
A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation
... and neuronal cell ...formation, neuronal and behavioral disturbances, and cell ...TAU-induced neuronal cell death was imaged by time-lapse microscopy in ...
15
miR-455 inhibits neuronal cell death by targeting TRAF3 in cerebral ischemic stroke
... The death rate of neuronal cell treated with sh-TraF3 was decreased after OgD for 24 hours, ...decreased neuronal cell death rate, and sh-TraF3 strengthened the ...increased ...
10
α-Synuclein and neuronal cell death
... α-Synuclein is a small protein that has special relevance for understanding Parkinson disease and related disorders. Not only is α-synuclein found in Lewy bodies characteristic of Parkinson disease, but also mutations in ...
14
<p>Zinc Oxide Nanoparticles Induce Ferroptotic Neuronal Cell Death in vitro and in vivo</p>
... a reduced number of neuronal cells. These results partially indicate that pulmonary exposed ZnONPs can aggregate in the brain via the above two ways to reach the central nervous system where neurotoxic effects ...
17
The therapeutic importance of understanding mechanisms of neuronal cell death in neurodegenerative disease
... massive neuronal loss, such as mutant tau models of FTDP-17 ...if neuronal death is mediated by a linear cascade, the likelihood that a therapeutic agent targeting any one of the insults within that ...
7
Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization
... various cell lines and animal models suggest that Ab may occur within neurons: (a) the Swedish mutation in the APP gene results in increased Ab accumulation in cultured cells (54); (b) Ab can be directly ...
12
Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons
... prejunctional neuronal VIP release ...improved neuronal survival and a rescue from mast cell-induced neuronal cell death of cultured myenteric neurons when exposed to ...of ...
10
Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice
... secondary neuronal cell death after trau- matic brain injury ...homologous cell injury after complement activation ...bystander" cell lysis after activation of the complement system ...
11
Original Article Paeoniflorin down-regulates the expression of NLRP1 and NLRP3 inflammasomes in rat hippocampal slices after oxygen-glucose deprivation
... Furthermore, it has been shown that the for- mation of NLRP1 and NLRP3 inflammasomes in ischemic stroke will eventually activate pre- cursor caspase-1 to cleaved caspase-1, which is able to produce both mature IL-18 and ...
8
N Methyl d Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection
... promotes neuronal cell ...propagating neuronal cell death, as typically seen in neurodegenerative processes ...further neuronal damage ...prevent neuronal cell ...
16
Synergistic effects of amyloid peptides and lead on human neuroblastoma cells
... induces neuronal death is still ...Aβ-mediated neuronal cytotoxicity by triggering or facilitating neuro-degeneration through a wide range of molecular events, eventually leads to neuronal ...
14
Brain tissue responses to ischemia
... enhance neuronal excitotoxici- ty by increasing vesicular glutamate release and neu- ronal excitability ...decreasing neuronal cell death in a global model of cerebral ischemia and attenuating ...
10
Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease
... endothelial cell releases factors that are injurious or toxic to neurons ...lar-mediated neuronal cell death in AD is derived from studies where direct co-culture of AD microvessels with ...
12
1 Neuron Cell Death 2
... Neuronal Cell Death in Neurodegenerative Diseases: Recurring Themes Around Protein 420. Handling[r] ...
16