neuronal migration
Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis
... regulates neuronal migration as well as neurite initiation and branching, through the ability of its F-BAR domain to deform membranes and form filopodia-like membrane ...
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Association of impaired neuronal migration with cognitive deficits in extremely preterm infants
... neocortical neuronal migration rather than on other relevant events occurring at a later time, such as the maturation of oligodendrocytes (10) and astrocytes (11), and had to select the stage ...which ...
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The dyslexia susceptibility KIAA0319 gene shows a specific expression pattern during zebrafish development supporting a role beyond neuronal migration
... in neuronal migration whereas subsequent work with double knock-out mouse models for both Kiaa0319 and its paralogue Kiaa0319-like reported effects in the auditory system but not in neuronal ...
10
Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration
... causes neuronal positioning errors that have been documented in knockout and RNA interference experiments ...the neuronal migration phenotypes, however, should not be seen as evidence that Stk25 and ...
10
The neuronal migration hypothesis of dyslexia : a critical evaluation 30 years on
... Knockout mice for dyslexia susceptibility gene homologs KIAA0319 and KIAA0319L have unaffected neuronal migration but display abnormal auditory processing.. The neurological basis of dev[r] ...
49
Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models
... I, neuronal heterotopia and other MCDs (Guerrini and Parrini, 2010; Stouffer et ...impaired neuronal migration phenotypes – similar to those seen in humans with SBH – have been achieved by ...
17
Conserved pattern of tangential neuronal migration during forebrain development
... of neuronal migration during brain development determine the distinct organization of adult ...tangential migration patterns across corresponding telencephalic territories in mammals and ...
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MIG 32 and SPAT 3A are PRC1 homologs that control neuronal migration in Caenorhabditis elegans
... Expression of additional MIG-32 homologs in the mammalian nervous system has been reported (Gunster et al., 1997; Jacobs et al., 1999; Kim et al., 2005; Leung et al., 2004; Molofsky et al., 2003; Nunes et al., 2001; ...
11
PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation
... in neuronal development ...for neuronal migration, but whether it is also involved in progenitor cell proliferation remains unknown ...and neuronal migration during cerebral cortical ...
11
Biased selection of leading process branches mediates chemotaxis during tangential neuronal migration
... during neuronal migration and axon guidance propose that directional sensing relies on growth cone ...during neuronal migration that might be extensively used in brain ...
10
α3β1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development
... during neuronal motility Earlier studies indicated that α 3 β 1 integrins could modulate neuron-glial recognition cues during neuronal migration and placement in cortex (Anton et ...affect ...
9
Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration
... Cortical organization was visualized using Nissl staining (supplementary material Fig. S1O-R) and in situ hybridization with layer-specific markers [Ctgf (subplate); Tle4 (subplate and L6); Er81 (Etv1 – Mouse Genome ...
12
Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord
... Neuronal migration is one of the early and critical steps of neural ...the migration of certain populations in the ventral spinal cord ...the migration of the dorsal neuroprogenitors and ...
10
Neuronal migration defects in the Loa dynein mutant mouse
... The Loa mouse represents an important model for the study of neurodegeneration. It should also, in principle, be useful in evaluating the role of dynein in other func- tions, such as neuronal migration. In ...
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Transcriptional co regulation of neuronal migration and laminar identity in the neocortex
... radial migration of projection neurons towards the CP does not follow a straight-forward route and includes phases of temporary migratory arrest and retrograde migration prior to entering the CP (Noctor et ...
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SARA regulates neuronal migration during neocortical development through L1 trafficking
... during neuronal development: neurons expressing either too little (Kishimoto et ...impaired migration and morphology/ orientation of their ...reduced migration towards the CP ...
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The zinc finger transcription factor GLI3 is a regulator of precerebellar neuronal migration
... nervous system (CNS) after E10.5 does not alter the formation of the precerebellar system. These results suggest that the abnormal migratory path of precerebellar neurons in Gli3 null mutants could be caused by: (1) ...
15
Identification of Genes That Regulate a Left-Right Asymmetric Neuronal Migration in Caenorhabditis elegans
... cell migration; study how left-right asymmetry and Hox gene regulation in mab-5(⫺) mutants, the descendants of QL migrate intersect in the context of cell ...
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Insights From Pretzel Syndrome: The Role of STRADA in Neuronal Migration and Cortical Development
... Tuberous sclerosis complex (TSC) is an autosomal dominant disorder resulting from mutations in the TSC1 or TSC2 genes, which encode TSC1 and TSC2 proteins, respectively (76, 77). Many individuals with TSC exhibit ...
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MR of Neuronal Migration Anomalies
... MR Diagnosis Lissencephaly Lissencephaly Polymicrogyria Polymicrogyria Schizencephaly bilateral vertical clefts: one narrow , one wide; polymicrogyria in and adjacent to clefts Schizence[r] ...
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