Neuropeptide Y
Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy
... determined. Neuropeptide Y (NPY), an endogenous anticonvulsant in the central nervous system, plays an important role in the regulation of neuronal ...
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Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus
... of neuropeptide Y (NPY) causes hyperphagia, hyperinsulinemia, and obesity, a response that is prevented by prior adrenalectomy (ADX) in ...receptor Y 1 and Y 5 mRNAs in the ventromedial ...
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Neuropeptide Y in the Medial Prefrontal Cortex Modulates Ethanol Consumption in Mice_ Perez-Heydrich.pdf
... Binge-like drinking behavior has been estimated to cause about 80,000 deaths in the United States annually and is a significant risk factor for developing ethanol dependence. This behavior is partially regulated by ...
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Neuropeptide Y Negatively Influences Monocyte Recruitment to the Central Nervous System during Retrovirus Infection
... We recently found that retrovirus infection in the CNS results in increased production of neuropeptide Y (NPY) by neurons (14). Further, deficiency in NPY significantly increased the inci- dence and ...
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Distribution of nitric oxide synthase and neuropeptide Y neurones during the development of the hippocampal formation in the rat
... immunohistochemistry. Neuropeptide Y (NPY) is the most abundant peptide in the ...ropeptide Y also modulates anxiety-related disorders, limbic epileptic seizures as well as learning and memory ...
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Dietary fat alters the response of hypothalamic neuropeptide Y to subsequent energy intake in broiler chickens
... Dietary fat affects appetite and appetite-related peptides in birds and mammals; however, the effect of dietary fat on appetite is still unclear in chickens faced with different energy statuses. Two experiments were ...
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Synergistic action of neuropeptide Y and adrenaline in the eel atrium
... of neuropeptide Y (NPY) in porcine brain (Tatemoto, 1982), NPY-like immunoreactivity has been detected in both the central and peripheral nervous system of mammals (reviewed by Dumont et ...
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Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1G93A mouse model of ALS
... indicates increased NPY expression by interneuron populations may be an advantageous intrinsic mechanism to counteract increased activity of cortical excitatory neurons. Therefore, our finding of increased density of ...
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Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight
... Abstract: Neuropeptide Y (NPY), colocalized with norepinephrine neuron, is known to modulate sympathetic activity and feeding behavior. Although experimental type 1 diabetes has increased sympathetic ...
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Novel dimeric DOTA-coupled peptidic Y1-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers
... NPY: neuropeptide Y; Nva: norvaline; PP: pancreatic polypeptide; PYY: peptide YY; RP-HPLC: reversed-phase high- performance liquid chromatography; TEA: triethylamine; TEAP: triethylammonium phosphate; TFA: ...
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Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction
... Acute myocardial infarction is associated with high levels of car- diac sympathetic drive, which is a poor prognostic indicator. 8 Prolonged sympathetic activation causes the release of the co- transmitter ...
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Pharmacological and functional similarities of the human neuropeptide Y system in C. elegans challenges phylogenetic views on the FLP/NPR system
... Global phylogenetic reconstructions indicate that the C. elegans NPR/FLP system is not directly orthologous to the human NPY system despite the latter being con- served in all bilaterians [6–8], and the NPR and NPY re- ...
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Neuropeptide Y-mediated sex- and afferent-specific neurotransmissions contribute to sexual dimorphism of baroreflex afferent function
... The neuropeptide-Y (NPY), as a neurotransmitter and potent vasoconstrictor, influences sympathetic activation together with others including norepinephrine or angiotensin- II ...
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Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects.
... Ewing sarcoma (ES) is an aggressive malignancy driven by an oncogenic fusion protein, EWS-FLI1. Neuropeptide Y (NPY), and two of its receptors, Y1R and Y5R are up-regulated by EWS-FLI1 and abundantly ...
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Original Article Biological effects of electrical stimulation on pelvic floor muscle strength and neuropeptide Y expression
... evaluate neuropeptide Y (NPY) expression and pelvic floor muscle strength of stress urinary incontinence (SUI) and diabetes rats before and after ES (electrical stimulation), and to compare the ...
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High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastases
... Ewing sarcoma (ES) develops in bones or soft tissues of children and adolescents. The presence of bone metastases is one of the most adverse prognostic factors, yet the mechanisms governing their formation remain ...
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Neuropeptide Y Increases Both Ingestion of a Self Selection Macronutrient Diet and Fos Expression in the Medial Amygdala of Rats
... It would be interesting to examine whether other neu- rotransmitter or neuropeptide would affect the MePD function and the modulation of goal-oriented food intake [14]. NPY, one of the most widely expressed ...
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Rodent models of human alcoholism : implications for a role of neuropeptide Y and corticotropin releasing factor
... Rodent models of alcoholism have been integral in discovering candidate genes and neurochemicals involved in this disease. Two promising candidates include neuropeptide Y (NPY) and corticotropin releasing ...
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Arcuate neuropeptide Y inhibits sympathetic nerve activity via multiple neuropathways
... (ArcN), and this action requires simultaneous withdrawal of tonic neuropeptide Y (NPY) sympathoinhibition. However, the sites and neurocircuitry by which NPY decreases SNA are unclear. Here, using designer ...
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Effects of opioid antagonists naloxone and naltrexone on neuropeptide Y induced feeding and brown fat thermogenesis in the rat Neural site of action
... specific neuropeptide Y antagonists are not yet available, previous studies had shown that the opioid antagonist naloxone blocked neuropeptide Y- induced feeding when both drugs were injected ...
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