Neuropeptide Y Gene
Reproduction and beyond, kisspeptin in ruminants
... Kisspeptin (Kp) is synthesized in the arcuate nucleus and preoptic area of the hypothalamus and is a regulator of gonadotropin releasing hormone in the hypothalamus. In addition, Kp may regulate additional functions such ...
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Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7
... and neuropeptide Y were used to detect specific human genomic DNA sequences in human-mouse somatic cell hybrid ...polypeptide gene (PPY) segregated with human chromosome 17, while the ...
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Neuropeptide Y Has a Protective Role during Murine Retrovirus-Induced Neurological Disease
... protein gene (Crhbp), the melanocortin 2 receptor gene (Mc2r), the neuropeptide Y gene (Npy), the prokineticin receptor 2 gene (Prokr2), the transcription factor gene Myc, ...
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Neuropeptide Y functions as a facilitator of GDNF induced budding of the Wolffian duct
... At 100 ng/ml of BMP4, budding was almost completely inhibited (Fig. 9C); however, addition of NPY resulted in restoration of budding, and of GFR1 localized zones of budding, to levels similar to those of WDs cultured ...
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Evolution of neuropeptide signalling systems
... of neuropeptide signalling that have been obtained recently through comparative analysis of genome/transcriptome sequence data and by ‘ deorphanisation ’ of neuropeptide ...30 neuropeptide signalling ...
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The Histopathological Difference Between Oral Lichen Planus and Oral Lichenoid Mucositis in Neurogenic Inflammation
... anti-calcitonin gene-related peptide (CGRP), anti-substance P (SP), anti-neuropeptide Y (NPY), anti-neurofilament heavy polypeptide (NF-H), anti-vasoactive intestinal peptide (VIP), anti-neurotrophin ...
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Characterizing the Role of the Neuropeptide Y-Y5R System in Breast Cancer
... Traditionally, GPCRs were considered to reside solely in the cell membrane and elicit their effect downstream through secondary effectors, however this notion has been dismissed with effects and localization in the ...
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Ethanol-induced locomotor sensitization and ethanol consumption : the role of neuropeptide Y
... leading to decreased CRE-mediated gene expression (Brandon et al., 1998). However, more recent evidence suggests that there is an increase in basal levels of PKA activity in RII β -/- mice. Specifically, ablation ...
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Pharmacological and functional similarities of the human neuropeptide Y system in C. elegans challenges phylogenetic views on the FLP/NPR system
... NPY2/7R gene prior to further local gene duplications generating the NPY1/4/6R and NPY5R genes during early deuterostome evolution [13, 34] indi- cating that human NPYR and ...
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The effect of hydro-alcoholic extract of ephedra pachyclada on serum concentrations of neuropeptide Y and ghrelin hormones and body weight in male rats
... Neuropeptide Y (NPY) is considered as the most abundant peptide hypothalamus and its most important effect is stimulating food ...NPY gene is the candidate gene for obesity; it is the ...
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Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells
... major by a monocyte/macrophage murine cell line [43]. Since infection of phagocytes is a crucial step for repli- cation of Leishmania major, inhibiting phagocytosis results in a protective action [44]. Moreover, the ...
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Effects of temperature on survival, moulting, and expression of neuropeptide and mTOR signalling genes in juvenile Dungeness crab (Metacarcinus magister)
... ganglia, Y-organ, heart, claw or thoracic muscle was used for initial PCR reactions, which consisted of 1 µl cDNA, 1 µl forward and 1 µl reverse primer (10 µmol l −1 ), 5 µl 2× PCR mastermix (Thermo Fisher ...
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Production, characterization, and expression of neuropeptide Y by human pheochromocytoma
... served in normals, it is likely that the higher NPY mRNA levels in adrenal tumors are caused by increased NPY gene expression and that this increase leads to increased NPY biosynthesis, [r] ...
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EFFECTS OF GENETIC POLYMORPHISMS ON EGG PRODUCTION IN INDIGENOUS NOI CHICKEN
... (Neuropeptide Y), VIP (Vasoactive intestinal peptide) and VIPR-1 (Vasoactive intestinal peptide receptor 1) had significant effects on egg ...DRD2 gene in turkeys and pointed out the associations ...
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Neuropeptide Y expression marks partially differentiated β cells in mice and humans
... Several studies have documented the reexpression of ear- ly developmental features and/or markers of related cell types (such as α cells) in diabetic β cells as a function of oxidative and ER stress (17, 18, 20). Our ...
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Neuropeptide y binding sites in rat brain and their relevance to the possible anxiolytic-like activity of receptor ligands
... immediate-early gene (lEG), also know n as a nuclear proto-oncogene, the m am m alian hom ologue of the v-fos oncogene found in two m urine osteogenic sarcoma viruses (for review see Doucet et ...
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Neuropeptide Y induces ischemic angiogenesis and restores function of ischemic skeletal muscles
... Endogenous NPY and Y2 receptors are angiogenic. To test whether the angiogenic activity of NPY plays a long- term role during tissue growth and development, we used rats overexpressing the NPY gene under the con- ...
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Epithelium generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness
... Two FOXP1 and FOXP4 DNA–binding sites are located in an evolutionarily conserved region approximately –0.8 kb to the tran- scriptional start of the mouse Npy gene (Supplemental Figure 2I). ChIP assays showed that ...
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Neuropeptides in asthma, chronic obstructive pulmonary disease and cystic fibrosis
... Neuropeptides, by definition, are peptides that are formed by the enzymatic processing of gene-encoded precursor molecules [21]. They are produced, stored, and secreted upon demand via regulated secretory path- ...
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The Caenorhabditis chemoreceptor gene families
... ing gene predictions in C. briggsae and C. remanei. Within each gene family, all candidate genes were identified by blastp searches of the latest WormBase protein predictions (the exact prediction version ...
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