neutralising antibody
Modulation of the virus receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivoescape from neutralising antibody
... Many of the variants isolated at post-mortem were resistant to neutralisation by homologous plasma and each resistant variant harboured mutations in the V5 loop of Env. Exchange of V5 loops between the parent virus and ...
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Enhanced neutralising antibody response to bovine viral diarrhoea virus (BVDV) induced by DNA vaccination in calves
... conventional DNA vaccines pSecTag/E2 and pTriExNS3 and plasmids expressing RIG-I agonist only presented both the positive and mock-vaccine groups. Our results showed that vaccines coexpressing E2t with a RIG-I agonist ...
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The association between age and the development of respiratory syncytial virus neutralising antibody responses following natural infection in infants
... age-specific neutralising antibody response patterns to natural infection were determined among infants of different ages in order to provide an accurate estimate of the youngest age at which infants mount ...
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Effect of sclerostin neutralising antibody on periarticular and systemic bone in a murine model of rheumatoid arthritis: a microCT study
... nature of the inflammatory insult in the immediate vicinity of the joint may be different from the insult at more distant sites. The ability of Scl-AbI to mediate endosteal but not periosteal bone formation in the ...
12
Seroprevalence of Rift Valley fever and lumpy skin disease in African buffalo (Syncerus caffer) in the Kruger National Park and Hluhluwe-iMfolozi Park, South Africa
... and neutralising antibodies against LSDV and RVFV using an indirect enzyme-linked immunosorbent assay (I-ELISA) and the serum neutralisation test ...RVFV neutralising antibodies were found in 5 of 66 ...
7
Studies on defective interfering Semliki Forest virus
... Brain and serum neutralising antibody titres in individual CFLP mice which had survived inoculation of 10 LD^q SFV + DI virus, or had received avirulent SFV intranasally.. Effect of DI S[r] ...
295
Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype
... the neutralising antibody treatment despite the fact that HMGB1 has also been shown to be a “non-core regulator” and strong inducer of Wnt/TCF-dependent transcription [30], suggests altered Wnt signaling is ...
9
Selective Persistence of HPV Cross-Neutralising Antibodies following Reduced-Dose HPV Vaccine Schedules
... Abstract: The duration of cross-neutralising antibody responses (cross-NAb) following HPV immunisation is unknown. We compared cross-NAb responses in cohort of girls who were either unimmunised or had ...
13
The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to alcelaphine herpesvirus-1-mediated malignant catarrhal fever in cattle
... virus-specific antibody titres and virus- neutralising antibody titres in blood plasma and nasal se- cretions were not enhanced by the inclusion of CpG ODN, and neither was the frequency of IFN-γ ...
11
Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies
... Morbillivirus neutralising antibodies are traditionally measured using either plaque reduction neutrali- sation tests (PRNTs) or live virus microneutralisation tests ...gene, neutralising antibody ...
9
Yeast expressed recombinant Hemagglutinin protein of Novel H1N1 elicits neutralising antibodies in rabbits and mice
... neutralizing antibody epitopes and the HA monomers are oligomerised into HA trimers ...a neutralising immune response from protein based vaccine, HA in its native form may be the best ...good ...
13
Duration of protective immunity and antibody responses in cattle immunised against alcelaphine herpesvirus-1-induced malignant catarrhal fever
... Current control measures for MCF rely on minimizing contact between carrier animals and susceptible live- stock. For AlHV-1 MCF, in areas close to wildebeest mi- gration routes in east Africa, this has the effect of ...
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Induction of neutralising antibodies by virus like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses
... There is an urgent need to develop novel approaches to vaccination against the emerging, highly pathogenic avian influenza viruses. Here, we engineered influenza viral-like particles (Flu-VLPs) derived from retroviral ...
7
Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010
... broadly neutralising, ...specific neutralising antibodies with similar potency and ...specific neutralising activity in five chronically infected patients from the Amsterdam cohort studies who ...
12
Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA
... Immunisation with chIL-10-Fc and fusion to generate hybrid- omas was carried out by Dundee Cell Products (DCP, Dundee, UK). Following fusion, hybridoma cultures were tested with recombi- nant chIL-10-V5H6 by dot-blot. ...
7
Towards a Belgian position on Brexit: Actively reconciling national and European interests Egmont Paper 99, November 2017
... This Egmont Paper is structured as follows. The first section discusses the main features of the UK’s withdrawal from the EU. It highlights the political context in which the Article 50 process is unfolding, flags the ...
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The immunogenicity of recombinant vaccines based on modified Vaccinia Ankara (MVA) viruses expressing African horse sickness virus VP2 antigens depends on the levels of expressed VP2 protein delivered to the host
... an antibody response following vaccination it is necessary that B-cell receptors bind to the foreign ...of antibody responses by re- combinant MVA vaccination are not ...improved antibody induction ...
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The Multilateral Tax Instrument: How to Avoid a Stalemate on Distributional Issues?
... See OECD, Neutralising the Effects of Hybrid Mismatch Arrangements, Action 2: 2015 Final Report, OECD/G20 Base Erosion and Profit Shifting Project (Paris: OECD Publishing, 2015); OECD, P[r] ...
24
ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice
... antibody levels at 28 d.p.i. The level of neutralising antibodies was also increased when tPA was utilised. However, ChAdOx1 MERS without tPA was still a potent vaccine candidate, inducing a high level of ...
9
Comparison of fluorescent antibody, neutralizing antibody, and complement enhanced neutralizing antibody assays for detection of serum antibody to respiratory syncytial virus
... A comparison of three assays for the detection of serum antibody to respiratory syncytial virus RSV was carried out on 47 serum samples obtained sequentially from infants and young child[r] ...
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