neutralizing antibody
Polyfunctional T Cell and Neutralizing Antibody Responses to ACAM2000TM Smallpox Vaccine Immunization in Primary Vaccinated Individuals
... We investigated whether the use of ACAM2000™ could induce T cell functions independently and/or simulta- neously and also specific neutralizing antibody in these individuals. Despite our small sample size, ...
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The interaction of influenza virus with neutralizing antibody
... induce neutralizing antibodies (Fan et al ., 1970). Specific antibody produced in the infection of mink with Aleutian disease virus (A D V ) also fails to neutralize infectivity ...induce ...
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Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Individual
... monoclonal antibody (MAb) was desirable, as this would conclusively prove that potent autologous neutral- ization was effected by a single antibody ...specific antibody genes mediating this early ...
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Control of Central Nervous System Viral Persistence by Neutralizing Antibody
... by neutralizing cell-free virus, thereby limiting spread, and also by eliminating virus-infected cells, via either complement- mediated cytotoxicity or Ab-dependent cell-mediated cytotox- icity (15, 16, ...of ...
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NEUTRALIZING ANTIBODY TO POLIOVIRUSES IN NORMAL HUMAN URINE
... Neutralizing activity was not detected in any of the urine concentrates by either test in the absence of antibody in the corresponding serum, except on one occasion in Subject 13 before [r] ...
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Structure of a Neutralizing Antibody Bound Monovalently to Human Rhinovirus 2
... of neutralizing monoclonal antibody (MAb) 3B10 has been determined to 25-Å resolution by cryoelectron microscopy and three-dimensional reconstruction ...of neutralizing MAb 8F5, which binds ...
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Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir
... the antibody accessibility of the underlying protein (16, ...map antibody binding and antibody neutralization activity depended not only on sequence, but also on gly- can occupancy (18, ...
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Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions
... When assessing gp120 specific Ab production upon STI, we did not observe a correlation between ASC fre- quencies and anti-gp120 IgG levels in the plasma. As all patients showed detectable anti-gp120 IgG levels in the ...
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Comparison of fluorescent antibody, neutralizing antibody, and complement enhanced neutralizing antibody assays for detection of serum antibody to respiratory syncytial virus
... A comparison of three assays for the detection of serum antibody to respiratory syncytial virus RSV was carried out on 47 serum samples obtained sequentially from infants and young child[r] ...
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Maternal but Not Infant Anti HIV 1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity
... HIV-1 vaccine efforts are focused on immunogen design capable of eliciting these bnAbs prior to exposure (19). Although current immunogens are unable to elicit bnAbs, it has been demonstrated that passive immunization of ...
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BIOLOGIC SIGNIFICANCE OF THE SECRETORY γA IMMUNOGLOBULINS
... Compari;on of measles neutralizing antibody in nasal secretions of children immunized with live or killed measles-virus vaccines.’. In contrast to tile serum antibody activity,[r] ...
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Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope Protein
... producing neutralizing or non-neutral- izing anti-E2 ...either neutralizing or non-neutralizing anti-E2 ...anti-E2 antibody-producing hybridoma clones (CBH4, -5, and -7); the viral RNA titer ...
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Differences in the antibody response to human immunodeficiency virus 1 envelope glycoprotein (gp160) in infected laboratory workers and vaccinees
... anti-V3 antibody was qualitatively different in the two groups. Antibody that can block the interaction between CD4 and gp120 was present at comparable levels in three vaccines and the lab ...workers. ...
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Antibody Protects Macaques against Vaginal Challenge with a Pathogenic R5 Simian/Human Immunodeficiency Virus at Serum Levels Giving Complete Neutralization In Vitro
... of neutralizing antibody in serum around or greater than 1:100 are required for sterile protection ...serum neutralizing antibody ti- ters of 1:380 are required to sterilely protect cotton ...
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Immunization with Modified Vaccinia Virus Ankara-Based Recombinant Vaccine against Severe Acute Respiratory Syndrome Is Associated with Enhanced Hepatitis in Ferrets
... strong neutralizing antibody and T-cell responses in monkeys (rhesus macaques) ...The neutralizing antibody response induced by recom- binant modified vaccinia virus Ankara (rMVA) expressing ...
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Characterization of Txndc5 as a Biomarker of Humoral Immunity to Respiratory Syncytial Virus Infections in Infants in Kilifi County Kenya
... and neutralizing antibody responses Further analysis to determine whether the functional antibody response to RSV following acute infection could be predicted on the basis of acute stage expression ...
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Expression of an Antigenic Adenovirus Epitope in a Group B Coxsackievirus
... protective neutralizing-antibody responses in mice against the vector CVB3 as well as against Ad2 argues forcefully for the stability of the insert during replication in mice and for correct presen- tation ...
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A preliminary randomized double blind placebo controlled trial of intravenous immunoglobulin for Japanese encephalitis in Nepal
... in neutralizing antibody titres among those treated with IVIG compared to ...JEV antibody positive children treated with IVIG exhibited higher (approximately 16 times higher) titres of ...
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Susceptibility and resistance to poliovirus-induced paralysis of inbred mouse strains.
... We were unable to correlate H-2 haplotype with high disease incidence, virus replication in the brain or spinal cord, neutralizing antibody or ELISA antibody responses, or TPRLF response[r] ...
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Stoichiometry of Murine Leukemia Virus Envelope Protein-Mediated Fusion and Its Neutralization
... by antibody by inserting an epitope from human immunodeficiency virus for a neutralizing antibody (2F5) into the surface (SU) or transmembrane (TM) protein of murine leukemia virus Env, along with ...
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