Neutron capture therapy (NCT)
Boron delivery agents for neutron capture therapy of cancer
... Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the nuclear capture and fission reactions that occur when the stable isotope, boron-10, is irradiated with ...
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Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer
... already close to the assumed lifetime tolerance doses following prior irradiation. Treatment approaches that allow dose escalation for tumor control and can effectively spare normal tissue during re-irradiation would be ...
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A realistic appraisal of boron neutron capture therapy as a cancer treatment modality
... Boron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear capture and fission reac- tions that occur when the stable isotope boron-10 is irradiated with ...
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Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
... boron neutron capture therapy [4,5], but also have potential in other fi elds of drug discovery, molecular imaging, and targeted radionuclide therapy ...
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Evaluation of Boron Content Liposome Modified Protein- Transduction Domains for Boron Neutron Capture Therapy
... radiation therapy as a treatment for malignant tumors becomes greater every year, but radiation therapy-resistant tumors still exist, and are known as convalescence ...Boron neutron capture ...
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Clinical trials for treating recurrent head and neck cancer with boron neutron capture therapy using the Tsing-Hua Open Pool Reactor
... boron neutron capture therapy (BNCT) may be a solution that could provide durable local control with tolerable ...epithermal neutron source for basic and clinical BNCT ...boron neutron ...
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Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy
... Abstract: The potential of boron-containing lipids with three different structures, which were intended for use in boron neutron capture therapy, was investigated. All three types of boron lipids ...
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Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism
... boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA) has been the most powerful drug owing to its ability to accumulate selectively within cancers through cancer-related amino acid ...
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Development of LINAC-Based Neutron Source for Boron Neutron Capture Therapy in University of Tsukuba
... boron neutron capture therapy (BNCT) have been conducted using research ...accelerator-based neutron source for ...the neutron target material. To generate sufficient neutron ...
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Thermal neutron Relative Biological Effectiveness factors for Boron Neutron Capture Therapy from in vitro irradiations
... thermal neutron factors is fundamental in Boron Neutron Capture ...fast neutron doses, although such an approach has been ...low-energy neutron beam has been used to determine thermal ...
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Boron neutron capture therapy – redefining radiotherapy
... radiation therapy for cancer’s that is based upon the selective uptake of non-radioactive boron ...a neutron beam causing boron ( 10 B) to be transformed into 11 B, which would disintegrate releasing an α ...
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Boron Neutron Capture Therapy (BNCT) - Low-Energy Neutron Spectrometer for Neutron Field Characterization -
... radiation therapy is be- ing developed, i.e., boron neutron capture therapy ...strong neutron source and re- lies only on available experimental nuclear ...based neutron source ...
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A History of 20th-Century Boron Neutron-Capture Therapy
... Ten international symposia during 2000-2016, one each in Argentina, Finland, Germany and Italy, three in the USA and three in Japan, attest to the vigor of modern NCT research. Further investigations of lipophilic ...
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In Vitro Evaluation System of Pharmacokinetics and Irradiation Effect in Boron Neutron Capture Therapy (BNCT) Using Three Dimensional Artificial Human Tumor Tissue Model
... DOI: 10.4236/jct.2019.1010071 841 Journal of Cancer Therapy Figure 3. Comparison of BxPC3 cell distribution and α -ray/recoiled Li particle track distribution in low magnification. (a)-(c): red fluorescent image ...
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Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses
... The most commonly recommended treatment for mel- anoma and EMPD of the genital region, including the vulva, penis, scrotum, and perianal area, is wide surgical excision of the lesion, with or without lymph node dis- ...
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<p>Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy</p>
... Combined-modality therapy is increasingly recom- mended in management to achieve a better outcome for ...radio- therapy than that of single modality, for that doxorubicin can enhance radiosensitivity in ...
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Shielding analyses of an AB-BNCT facility using Monte Carlo simulations and simplified methods
... Boron neutron capture therapy (BNCT) is a form of targeted radiotherapy that relies on the thermal neutron capture reaction of boron-10, leading to two heavy charged particles to kill ...
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Direct Synthesis of Li3N Thin Layer on Lithium Target Surface for BNCT in N2 Gaseous Conditions
... Implemented deployment of accelerator-driven neutron source for boron neutron capture therapy (BNCT) is scheduled in 2014 in National Cancer Center, Japan. This BNCT system was designed with ...
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Low Temperature and Pressure Synthesis of Lithium Nitride Compound with H2O Addition on Lithium Target for BNCT
... Implemented deployment of accelerator-driven neutron source for Boron Neutron Capture Therapy (BNCT) is scheduled in 2013 in National Cancer Center, Japan. This BNCT system was designed with ...
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3 (4 Dihydroxyborylphenyl)cyclobutanone1
... chemical therapy or radiation therapy; boron neutron capture therapy (BNCT) has been recently considered as an alternative useful method for treating hepatoma (Aris et ...
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