Newborn Rats
Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1
... Wistar rats (200 – 220 g) were pur- chased from the Center for Experimental Animals of China Medical ...full-term newborn rats from twelve litters were randomly marked and assigned to two groups and ...
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The effect of maternal diabetes on pancreatic islets in newborn rats: a quantitative and immunocytochemical study
... The effect of diabetes during pregnancy on the endocrine pancreas of the new- born has been studied before, but a detailed morphometric immunocytochem- ical study is not available. The aim of this study was to ...
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Activated ClC-2 Inhibits p-Akt to Repress Myelination in GDM Newborn Rats
... of newborn rats’ cerebral white matter with gestational diabetes mellitus ...fetal rats after E18 stage, and elevated the level of TNF-α and iNOS in white matter at P0 and P3 stage of newborn ...
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Original Article Effects of dexmedetomidine on the protection of hyperoxia-induced lung injury in newborn rats
... A previous study showed that high dose Dex sig- nificantly attenuates ventilator-induced lung injury via the regulating of pulmonary inflamma- tion [17]. In addition, treated with Dex result in a lower inflammation, ...
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Mathernal diabetes chenges aqueduct of sylyius volume in newborn rats
... equal volume of citrate buffer. After parturition 1 pup were randomly selected from each litter, their brain dissected, fixed in 10% formalin, sectioned in 7 ìm thicknesses and stained by H.E. By applying stereological ...
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Social Deprivation of Newborn Rats Modifies Exploratory and Defensive Behavior at Mature Age
... WAG/Rij rats genetically predisposed to ab- sence epilepsy, sensory deprivation in the first 3 weeks of life leads to an earlier manifestation of the pathology ...of rats, experiments with the removal of ...
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Maternal Response of Perinatally Underfed Wistar Virgin Females Exposed to Newborn Rats
... the newborn to present non-adaptive behavioral responses later in ...when rats were gently rotating between litters did not affect the body and brain weight of pups, but it may have inconsistently in- ...
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Oxygen-Induced Retinopathy in Newborn Rats: Effects of Prolonged Normobaric and Hyperbaric Oxygen Supplementation
... All 16 rats from the two litters of group 1 (treated with normobaric 80% 02 for five days followed by room air for five more days) had tortuous, congested retinal vessels with significan[r] ...
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Original Article Inhibition of TGF-β-Smad signaling attenuates hyperoxia-induced brain damage in newborn rats
... All animal experiments were carried out in ac- cordance with institutional guidelines concern- ing animal use and care at West China Medical Center, Sichuan University. Pregnant Sprague- Dawley rats were obtained ...
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Generation of defective virus after infection of newborn rats with reovirus.
... To determine whether defective virions were generated during the chronic stage of infection, virus isolated from brains 30 days after subcutaneous inoculation was concentrated and amplif[r] ...
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Original Article Impaired expression of IRS-2 and GCK contribute to glucose dysregulation during catch-up growth in immature rats after intrauterine growth restriction
... Wistar rats. The IUGR rats and normal weight controls were investigated at newborn, 3-week-old and 8-week-old for the level of fasting plasma glucose (FPG) and fasting serum insulin ...8-week-old ...
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Original Article Glucocorticoid attenuates hyperoxia-induced lung injury in neonatal rat and inhibits RAGE and NF-kB expression
... Sprague-Dawley newborn rats were randomly divided into three groups (n=8): sham control (control group); hyperoxia-induced acute lung injury (model group) and hyperoxia- induced acute lung injury treated ...
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Effect of maternal exposure to octylphenol (4 tert octylphenol) on the growth of the adrenal gland in male albino rats
... of newborn rats of the preg- nant female treatment with dose low-and high-4-tert- octyl phenol compared to the control group and did not observe any superficial changes or behavioral on new- borns male ...
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Bisphosphonate action Alendronate localization in rat bone and effects on osteoclast ultrastructure
... Studies of the mode of action of the bisphosphonate alendronate showed that 1 d after the injection of 0.4 mg/kg [3H]alendronate to newborn rats, 72% of the osteoclastic surface, 2% of the bone forming, and ...
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A comparison of E15.5 fetus and newborn rat serum proteomes
... Complement acts as a rapid and efficient immune surveil- lance system and contributes substantially to physiologic homeostasis by eliminating cellular debris and infectious microbes [32]. In our study, we found that the ...
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Polyoma virus mutant with normal transforming ability but impaired tumorigenic potential.
... DISCUSSION We have shown that cloned DNA from the P155 mutant of Py virus is much less tumorigenic than wild-type DNA when injected into newborn rats, and that cells transformed in vitro[r] ...
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Profiles of the auditory epithelia related microRNA expression in neonatal and adult rats
... with newborn rats (P0) included negative regulation of epithe- lial cell differentiation, common-partner SMAD protein phosphorylation, mesenchymal-epithelial cell signaling, regulation of TGF-β2 ...
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Protein X of Borna Disease Virus Inhibits Apoptosis and Promotes Viral Persistence in the Central Nervous Systems of Newborn-Infected Rats
... in newborn-infected Lewis rats. Lewis rats infected with BDV as neonates usually do not develop neurological symptoms and survive infection due to the immaturity of the immune system at their first ...
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Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia
... Background: While additional oxygen supply is often required for the survival of very premature infants in intensive care, this also brings an increasing risk of progressive lung diseases and poor long-term lung ...
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Application of three dimensional culture conditions to human embryonic stem cell derived definitive endoderm cells enhances hepatocyte differentiation and functionality
... Alginate scaffold has been found to promote cells from the liver of newborn rats to differentiate into functional liver tissues. 20 To evaluate whether the Algimatrix 3D culture has any advantage over ...
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