NF-Y
NF-Y controls transcription of the minute virus of mice P4 promoter through interaction with an unusual binding site.
... was NF-Y, also designated CP1, CBF, and YEBP, a protein (references 12, 29, and 56 and references therein) which bound to a Y-box-related motif (GACCAACCAT) overlapping the PRE and E ...and ...
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Epigenetic role of the nuclear factor NF-Y on ID gene family in endometrial tissues of women with endometriosis: a case control study
... [35]. NF-Y regulates the balance between prolifera- tion and differentiation states through the recruitment of RNA polymerase II and communication with tran- scription factors and the enzymes binding to the ...
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Nuclear factor-Y (NF-Y) regulates transcription of mouse Dmrt7 gene by binding to tandem CCAAT boxes in its proximal promoter
... factor NF-Y and the Dmrt7 pro- moter. Finally, our study showed that NF-Y up-regulated the expression of Dmrt7 by binding to two tandem CCAAT-boxes in the proximal promoter region of the ...
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NF-Y loss triggers p53 stabilization and apoptosis in HPV18- positive cells by affecting E6 transcription
... and NF-YA-targeting shRNAs ...upon NF-YA loss, considering a threshold of ...[26]. NF-Y sites were over-represented in down-regulated genes (p-value= 2,41923E-14), indicating that ...
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Tumor necrosis factor alpha eliminates binding of NF Y and an octamer binding protein to the lipoprotein lipase promoter in 3T3 L1 adipocytes
... posttranscriptionally. To elucidate further the transcriptional mechanism of TNF alpha inhibition of LPL gene transcription, transfection analysis was used to locate the site(s) of the LPL promoter that imparts the TNF ...
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Nuclear Factor Y (NF Y) Modulates Encystation in Entamoeba via Stage Specific Expression of the NF YB and NF YC Subunits
... the NF-Y complex binds to a CCAAT motif (21, ...to NF-YA and NF-YC, which resulted in the presence of a supershift (SS) band; EMSA performed with the control actin antibody did not result in a ...
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Light Regulated Osa miR169e Is Implicated during Priming under High Temperature Stress in Rice
... We had earlier reported that integration of light and temperature signaling pathways in plants influence the miR based regulatory networks to regulate plant growth and development [32]. In this study, we report that ...
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Characterization of the 5′-flanking region of the mouse asparagine-linked glycosylation 12 homolog gene
... Fig. 3. Effect of ERSE and its flanking region on promoter activity of the mouse ALG12 gene in Neuro2a cells. Thirty-six hours after transfection of the indicated reporter construct, luciferase activity was measured as ...
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Activation of Transcription of the Human Cytomegalovirus Early UL4 Promoter by the Ets Transcription Factor Binding Element
... the NF-Y binding site and the site 2 region upstream of the early viral UL4 promoter (E1) were major upstream regulatory ...The NF-Y binding site did not play a significant role in UL4 ...
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Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma
... unrestrained NF-YA l expression is highly cytotoxic and induces p53-dependent apoptosis ...novel NF-YA x -dependent necroptosis mech- anism may be restricted to genotoxic-stress under p53 compromised ...
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DEK binding to class II MHC Y box sequences is gene and allele specific
... conserved Y-box regulatory element in MHC class II gene promoters pointed to the Y box as one possible related ...site. NF-Y binding to the MHC class II gene Y box anchors a complex ...
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Regulation of the human topoisomerase IIℓ: a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry
... Thus, in addition to NF-Y, other transcription factors must also be important for the regulation of topoisomerase Ila gene expression... GC boxes are another common promoter element, oft[r] ...
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LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition
... factor NF-Y as a mediator of LTR12 promoter activity and HDAC inhibitor-induced apoptosis, in the context of widespread genomic binding of NF-Y to specific LTR12 ...
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Role of Nuclear Factor Y in Stress-Induced Activation of the Herpes Simplex Virus Type 1 ICP0 Promoter
... whether NF-Y associates with the ICP0 promoter at ⫺ 708 TSS in Vero cells, gel shifts with consen- sus NF-Y, wild-type, and mutant ICP0 probes were carried out using Vero cell nuclear ...
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Herpesviruses and the Unfolded Protein Response
... Endoplasmic Reticulum Stress- Induced Formation of Transcription Factor Complex ERSF Including NF-Y (CBF) and Activating Transcription Factors 6 and 6 That Activates the Mammalian Unfol[r] ...
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Functional Interaction of Nuclear Factor Y and Sp1 Is Required for Activation of the Epstein-Barr Virus C Promoter
... Plasmids. The expression vector for dominant negative NF-YA, dnNF-YA, was kindly provided by R. Mantovani (Universita` di Milano, Milan, Italy). Its empty vector was engineered by excision of the dnNF-YA exon with ...
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Human Herpesvirus 8-Encoded vGPCR Activates Nuclear Factor of Activated T Cells and Collaborates with Human Immunodeficiency Virus Type 1 Tat
... for NF-AT activation ...tested NF-AT activation by vGPCR in T- lymphoid (Jurkat) cells because T cells express high levels of NF-AT protein, making it easy to measure NF-AT ...an NF-AT ...
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A functional genomics screen for microRNA regulators of NF-kappaB signaling
... endogenous NF-B ...the NF-B pathway, we co-transfected the mimics with one of two independent small interfering RNAs (siRNAs) against the p65 subunit of NF-B (efficacy of the siRNAs is demonstrated ...
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Analysis of an ankyrin like region in Epstein Barr Virus encoded (EBV) BZLF 1 (ZEBRA) protein: implications for interactions with NF κB and p53
... with NF- B ...between NF- B and p53 proteins an unfortunate consequence of NF-B inhibition by ZANK would also unavoidably be inactivation of ...
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Study of the Implementation of Ad hoc On Demand Distance Vector (AODV) Protocol in Network Simulator (NS 2)
... set ns [new Simulator] set nf [open out.nam w] $ns namtrace-all $nf # Define a ’finish’ procedure proc finish { } { global ns nf $ns flush-trace #Close the trace file close $nf #Execute [r] ...
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