Ni/sub 80/Fe/sub 15/Mo/sub 5/
Sub-10 nm Cu<sub>5</sub>FeS<sub>4</sub> cube for magnetic resonance imaging-guided photothermal therapy of cancer
... (Cu 5 FeS 4 cube) with a mean diameter of 5 ± 1 nm based on a facile one-pot pyrolysis method has been prepared ...Cu 5 FeS 4 cube not only possesses strong NIR absorption like copper sulfide but ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... All animals were kept in stress-free, hygienic, and animal- friendly conditions (relative humidity 60% ± 10%, room tem- perature 20 ° C ± 2 ° C, and 12-hour light/dark cycle). Food and water were available ad libitum. ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Figure 15. In the current work, the MTT assay showed that Fe 3 O 4 -PLGA-PEG 2000 -doxorubicin has dose-dependent and time-dependent cytotoxicity against the A549 lung can- cer cell line (IC 50 ...that ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... ± 15% humidity, and 12 h light/dark cycle) and had free access to water and ...Then, Fe 3 O 4 -PLGA or Fe 3 O 4 -PLGA-cRGD NPs at a final dosage of 1 mg lyophilized powder dissolving 1 mL phosphate- ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... The in vitro bioassay, as shown in Figure 9, tells us that, after 72 hours of treatment, neither gallic acid nor FCG was toxic to a normal human fibroblast (3T3) cell line tested using various doses (0.47, 0.94, 1.88, ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... and 5-Br-Tet from Fe 3 O 4 ...with Fe 3 O 4 ...with 5-BrTet only decreased the speed of tumor growth and had much less effect on overcoming multidrug resistance than did Fe 3 O 4 - ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... cells/mL with RPMI-1640. The adjusted cells were placed in a 96-well microtiter plate in 200 µ L aliquots and cultured in the presence of T-lymphocytes mitogen (5 µ g/mL Con- canavalin A [ConA]) (Sigma Chemical ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4 </sub>and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells
... milk powder dissolved in Tris-buffered saline (TBS) at room temperature for one hour. The primary P-gp antibody was mouse monoclonal anti-human antibody (Neomarkers, Fremont, CA, USA). The secondary antibody was alkaline ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... Forty-two mice were randomly assigned to either the non- exercised control group (n = 6) or exercise groups (n = 36). Thirty-six mice were placed into plastic cylinders (23 cm tall × 14 cm diameter) containing water ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... Elemental analysis was performed using scanning electron microscopy-energy dispersive x-ray spectroscopy (SEM-EDS, EDAX 9100; EDAX International, Prairie View, IL). X-ray diffraction data were collected using an XD-D1 ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... The functional groups on the particles were identified by Fourier transform infrared (FT-IR) spectroscopy using a JASCO IR-4200 (JASCO Inc, Easton, MD, USA). The per- centage of Dex and alendronate that were coated onto ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... to Fe 3 O 4 NPs (100 µ g/mL), there was a progressive decrease in the activity of MEP-induced channels, which occurred at the level of hyperpolarizing potentials ranging between − 80 and − 200 ...of ...
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Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... aa, acetoacetate; ab, anabasine; ace, acetate; ach, acetylcholine; aco, aconitate; act, acetone; aD, acetamide; ah, aminohippurate; ala, alanine; all, allantoin; arg, arginine; asn, asparagine; Ben, benzoate; Bet, ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... group) Fe 3 O 4 -MNPs, were dissolved in normal saline and intravenously (iv) injected into mice ...for 5 minutes at 4 ° C to separate plasma and blood ...− 80 ° C for determination of ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean diameter of 98 ± 22 and 101 ± 19 nm, respectively (Figure ...2B–E). ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... MgNPs-Fe 3 O 4 alone reduced the viability of LNCaP and PC-3 cells, but had little or no effect on the viability of DU145 and PrSC cells (Figure 5). These results suggest that the cytotoxicity of ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... The procedures for generation and drug loading of TfDMP are shown in Figure 1. By coupling GA with amino- immobilized Fe 3 O 4 @SiO 2 , the surface of the magnetic nanoparticle can be modified with both carboxyl ...
9
Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... of Fe 3 O 4 @ SiO 2 nanoparticles, followed by electrostatic adsorption of VEGF ...The Fe 3 O 4 /SiO 2 /PEI/VEGF shRNA nano- composites exhibited negligible hemolysis against human blood, and very low ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... GA (Kanion Pharmaceutical Co., Ltd, Jiangsu, China) was dissolved in dimethyl sulfoxide (DMSO; Sigma Aldrich, St. Louis, MO), stored at - 20 ° C, and then diluted as needed in RPMI 1640 medium (Gibco/BRL, ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... with 5 µ L MTT (5 mg/mL) and incubated at 37 ° C for four hours, dimethyl sulfoxide 100 µ L was added to each well and the plates were gently shaken for 10 ...
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