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Nipah virus

Antibody Prophylaxis and Therapy against Nipah Virus Infection in Hamsters

Antibody Prophylaxis and Therapy against Nipah Virus Infection in Hamsters

... Nipah virus (NiV), a member of the Paramyxoviridae family, causes a zoonotic infection in which the reservoir, the fruit bat, may pass the infection to pigs and eventually to ...

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Nipah virus persists in the brains of nonhuman primate survivors

Nipah virus persists in the brains of nonhuman primate survivors

... Nipah virus (NiV) is a negative-sense RNA virus classified in the genus Henipavirus (Mononegavirales: Paramyxoviridae) (1). In humans, NiV causes henipavirus encephalitis (International ...

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Nipah virus infection and glycoprotein targeting in endothelial cells

Nipah virus infection and glycoprotein targeting in endothelial cells

... pathogenic Nipah virus (NiV) causes fatal respiratory and brain infections in animals and ...the virus to overcome the blood-brain-barrier (BBB) and to subsequently infect the brain ...lateral ...

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Quantitative estimation of Nipah virus replication kinetics in vitro

Quantitative estimation of Nipah virus replication kinetics in vitro

... of Nipah virus N gene sequence Initial amplification of Nipah virus sequences was accom- plished using the conventional RT-PCR performed in a PTC-200 thermal cycler (Bio-Rad Laboratories, ...

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Novel Nipah Virus Immune-Antagonism Strategy Revealed by Experimental and Computational Study

Novel Nipah Virus Immune-Antagonism Strategy Revealed by Experimental and Computational Study

... Nipah virus is an emerging pathogen that causes severe disease in ...of Nipah virus immune antagonists. Indi- vidual Nipah virus immune antagonists (phosphoprotein and V and W ...

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Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress

Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress

... ABSTRACT Nipah virus (NiV), a paramyxovirus in the genus Henipavirus, has a mor- tality rate in humans of approximately ...of virus-like particles ...

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Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells

Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells

... Ebola virus (EBOV) and Nipah virus (NiV) infection of humans can cause fatal disease and constitutes a public health ...restricts virus infection and is susceptible to GP-driven ...in ...

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Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain

Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain

... Sendai virus P implicated in L binding are indicated (39), as are the residues in a corresponding basic patch of Nipah virus ...stomatitis virus (43) (B) Model of the organization of the ...

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Exploring the Human-Nipah Virus Protein-Protein Interactome

Exploring the Human-Nipah Virus Protein-Protein Interactome

... of Nipah-human PPIs, DNAs encoding each viral protein fused to a tandem affinity purification (TAP) tag sequence at either the amino or carboxy terminus were transfected into HEK293T ...Briefly, Nipah ...

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Novel Functions of Hendra Virus G N-Glycans and Comparisons to Nipah Virus

Novel Functions of Hendra Virus G N-Glycans and Comparisons to Nipah Virus

... Hendra virus (HeV) and Nipah virus (NiV) are reportedly the most deadly pathogens within the Paramyxoviridae family. These two viruses bind the cellular entry receptors ephrin B2 and/or ephrin B3 via ...

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Selective receptor expression restricts Nipah virus infection of endothelial cells

Selective receptor expression restricts Nipah virus infection of endothelial cells

... Nipah virus (NiV) is a highly pathogenic paramyxovirus that causes severe diseases in animals and ...systemic virus spread via the vascular system, EC in brain and lung are preferentially infected ...

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Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

... Nipah virus (NiV) is a highly lethal paramyxovirus that recently emerged as a causative agent of febrile encephalitis and severe respiratory disease in ...

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The YPLGVG sequence of the Nipah virus matrix protein is required for budding

The YPLGVG sequence of the Nipah virus matrix protein is required for budding

... Background: Nipah virus (NiV) is a recently emerged paramyxovirus capable of causing fatal disease in a broad range of mammalian hosts, including ...Hendra virus (HeV), they comprise the genus ...

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Purification and Characterization of Nipah Virus Nucleocapsid Protein Produced in Insect Cells

Purification and Characterization of Nipah Virus Nucleocapsid Protein Produced in Insect Cells

... Nipah virus (NiV), the etiologic agent for both human and swine diseases, was first isolated from the cerebrospinal fluid of human patients and classified in the family Paramyxoviridae ...and Nipah ...

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Invasion of the Central Nervous System in a Porcine Host by Nipah Virus

Invasion of the Central Nervous System in a Porcine Host by Nipah Virus

... for Nipah virus RNA starting at 2 dpi, either by both sets of primers located within the N and F genes, or with the N gene primers ...of virus isolation and RT-PCR on nasal and pharyngeal swabs in ...

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Nipah Virus Infection

Nipah Virus Infection

... for Nipah virus IgG ...anti-Nipah virus neutralizing antibodies, one was a staff nurse who also had magnetic resonance imaging (MRI) changes similar to those seen in acute ...

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Membrane Fusion Tropism and Heterotypic Functional Activities of the Nipah Virus and Hendra Virus Envelope Glycoproteins

Membrane Fusion Tropism and Heterotypic Functional Activities of the Nipah Virus and Hendra Virus Envelope Glycoproteins

... Nipah virus (NiV) and Hendra virus (HeV) are novel paramyxoviruses from pigs and horses, respectively, that are responsible for fatal zoonotic infections of ...vaccinia virus system and a ...

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Molecular characterization of Nipah virus from Pteropus hypomelanus in Southern Thailand

Molecular characterization of Nipah virus from Pteropus hypomelanus in Southern Thailand

... Background: Nipah virus (NiV) first emerged in Malaysia in 1998, with two bat species (Pteropus hypomelanus and P. vampyrus) as the putative natural reservoirs. In 2002, NiV IgG antibodies were detected in ...

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Mathematical Analysis of Nipah Virus Infections Using Optimal Control Theory

Mathematical Analysis of Nipah Virus Infections Using Optimal Control Theory

... of Nipah Virus (NiV) using op- timal control technique is studied in this ...of Nipah virus can be controlled effectively if we ap- ply control strategy at early ...

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Recombinant Nipah Virus Vaccines Protect Pigs against Challenge

Recombinant Nipah Virus Vaccines Protect Pigs against Challenge

... Nipah virus (NiV), a member of the family Paramyxoviridae, genus Henipavirus, emerged in Malaysia in 1998 as an etiolog- ical agent in an outbreak of severe febrile encephalitis in hu- mans, with a clinical ...

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