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Non-Small Cell

Crizotinib in non small cell lung cancer

Crizotinib in non small cell lung cancer

... [16] Camidge, D.R., Bang, Y.J, Kwak, E.L, Iafrate, A.J., Va- rella-Garcia, M., Fox, S.B., Riely, G.J., Solomon, B., Ou, S.H., Kim, D.W., Salgia, R., Fidias, P., Engelman, J.A., Gandhi, L., Jänne, P.A., Costa, D.B., ...

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Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

... Background: Non-small cell lung cancer (NSCLC) is the most frequent cause of cancer deaths worldwide. The targeted therapy had made important progress in recent years, but few potential predictive ...

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Surgical treatment in non small cell lung cancer with pulmonary oligometastasis

Surgical treatment in non small cell lung cancer with pulmonary oligometastasis

... metastatic non-small cell lung cancer is still controversial, many previous research [10, 14 – 16] have reported parts of selective patients that benefited from it, but radical resection of the ...

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LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1

<p>LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1</p>

... The latest cancer statistic data showed that lung cancer is the secondary most common types of malignancy in both men (following prostate cancer) and women (following breast cancer), while lung cancer is the most common ...

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FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

... to non-small cell lung cancer (NSCLC) treatment, and this causes T cell activation and T cell infiltration to tumor tissue through the blockade of the interaction between programmed ...

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Cetuximab and biomarkers in non-small-cell lung carcinoma

Cetuximab and biomarkers in non-small-cell lung carcinoma

... In non-small-cell lung cancer (NSCLC), as in several other cancer types, the epidermal growth factor receptor (EGFR) and its downstream signaling components represent a key axis that has been found ...

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Vaccines in Non Small Cell Lung Cancer

Vaccines in Non Small Cell Lung Cancer

... 80%. Non-small cell lung cancer stage IIIB and IV patients were enrolled between 2000 and 2002 by centers of Canada and the United Kingdom, including a total of 171 ...a non-significant ...

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Cell-free DNA in non-small cell lung cancer

Cell-free DNA in non-small cell lung cancer

... early-stage non-small cell lung can- cer ...of non-small cell lung cancer have revealed molecular information used for systemic can- cer therapy targeting metastatic disease, ...

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Emerging therapies for non-small cell lung cancer

Emerging therapies for non-small cell lung cancer

... T cell (CAR-T) have been accelerated in hematological malignancies especially for CD19-targeted CAR-T-cell therapy in leukemia [214– ...regarding non-small cell lung can- cer ...

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Therapeutic vaccines in non-small cell lung cancer

Therapeutic vaccines in non-small cell lung cancer

... Following the results of the Phase II trial, MAGE-A3 as adjuvant non-small cell lung cancer immunotherapy (MAGRIT), the largest Phase III lung cancer study in history, was designed and is ongoing. ...

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Characterization and selective incorporation of small non-coding RNAs in non-small cell lung cancer extracellular vesicles

Characterization and selective incorporation of small non-coding RNAs in non-small cell lung cancer extracellular vesicles

... EV small non-coding RNAs and cancer, due to their regulatory functions in gene ...of small non-coding RNA expression and their incorporation into EVs is important for cancer ...of small ...

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Adjuvant Chemotherapy of Non-Small Cell Lung Cancer

Adjuvant Chemotherapy of Non-Small Cell Lung Cancer

... Robert Pirker Approximately 25-30% of patients with non-small cell lung cancer (NSCLC) present with early stage disease and undergo surgery with curative intent. Despite complete tumor resection, ...

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Pemetrexed as first-line therapy for non-squamous non-small cell lung cancer

Pemetrexed as first-line therapy for non-squamous non-small cell lung cancer

... Abstract: Pemetrexed is a new cytotoxic agent that is a standard of care for the second-line treatment of non-small cell lung cancer (NSCLC) and in combination with cisplatin in treatment of malignat ...

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Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation

Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation

... A 68-year-old man presented with cough. CT scan confirmed the presence of an irregular pleural-based mass measuring 3.1 × 4.2 × 4 cm in the right upper lobe. PET scan re-demon- strated the primary lesion and in addition ...

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Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

... in non- small cell lung cancer (NSCLC) remain ...NSCLC cell lines, A549 and 95D by RNA ...inhibited cell growth and colony formation, induced cell arrest at G0/G1 phase and ...

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Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines

Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines

... Protein expression was determined by immunoblotting with protein extracts prepared with the Compartmental Protein Extraction Kit according to the manufacturer's instructions (Chemicon International, Hampshire, United ...

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lncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p

lncRNA PCAT6 promotes non-small cell lung cancer cell proliferation, migration and invasion through regulating miR-330-5p

... The siRNA oligonucleotides were synthesized by Shanghai GenePharma Co. Ltd. (Shanghai, China), and the siRNA sequence of PCAT6 was as follow: siRNA negative control (si-NC) (5 ′ -GCGACCAA CGCCTTGA TTG-3 ′ ) and si-PCAT6 ...

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Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

... relatively small scale of the FUSCC cohort and to avoid bias from the few events of death, the end point for this derivation cohort was defined by PFS instead of OS for analyzing the association of PDPN and ...

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Gefitinib for advanced non small cell lung cancer

Gefitinib for advanced non small cell lung cancer

... Yang CH, Fukuoka M, Mok TS, Wu YL, Thongprasert S, Saijo N, et al. Final overall survival (OS) results from a phase III, randomised, open-label, first-line study of gefitinib (G) v carboplatin/paclitaxel (C/P) in ...

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Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-&kappa;B, uPA activator, and MMP-9

Delta-tocotrienol inhibits non-small-cell lung cancer cell invasion via the inhibition of NF-&kappa;B, uPA activator, and MMP-9

... on cell proliferation, migration, invasion, adhesion, and aggregation capabilities were investigated using different cell-based ...inhibited cell proliferation, cell migration, invasion, ...

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