Non small cell carcinomas
Original Article Relationship of Fas, FasL, p53 and bcl-2 expression in human non-small cell lung carcinomas
... lung carcinomas. There were 58 squamous cell carcinomas, 32 adenocarcinomas, 3 adenosquamous carcino- mas (ASCs), 3 bronchioloalveolar carcinomas (BACs), 6 large cell carcinomas, ...
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Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas
... squamous cell subtype of NSCLC may pave the way for specific targeted therapies in this NSCLC ...squamous cell carcinoma appears neglected as far as targeted molecular therapies are con- sidered, being most ...
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Evaluation of Epidermal Growth Factor Receptor by Mutation Specific Immunohistochemistry in Non Small Cell Lung Carcinomas
... “small cell” and “non–small cell” ...the non– small cell group is ...or non small cell carcinoma not otherwise specified, had a better survival ...
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Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas
... colorectal carcinomas (35), as well as non-Hodgkin’s lymphomas (36), indicate a poten- tial importance of the protein in distinguishing be- tween malignancies with different biological behav- ...
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Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
... versus non- metastatic), testosterone levels, and prior chemotherapy ...pure small-cell carcinomas and variants with neuroendocrine differentiation; (2) replacing the pre- versus ...
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Prognostic Role of miR 205 in Early Stage (T1N0) Non Small Cell Lung Cancer
... regulate cell differentiation, apoptosis, and ...several carcinomas, in- cluding non-small cell lung cancer (NSCLC); moreover, aberrant expression of miRNAs is significantly related to ...
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Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas
... The cell lines SW480 (human colon carcinoma) and MDA-MB231 (human breast cancer) carry K-ras mutations at codons 12 and 13, respec- tively, and were used as positive controls for K-ras mutation analysis ...
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Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches
... Activated natural killer cells (CD57 + granzyme B+ CD45RO−) have a high cytotoxic potential [48], suggest- ing that the activation of these cells could have import- ant therapeutic implications. Overall, quantities of ...
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Case Report Parotid gland and cerebellum metastasis of lung cancer: a case report
... Squamous cell carcinomas accounts for ap- proximately 30% of all non-small cell carcinoma of the lungs ...primary small-cell carcinoma [3-7] and adenocarcinoma [8]. Lung ...
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MicroRNA-148a suppresses proliferation and invasion potential of non-small cell lung carcinomas via regulation of STAT3
... After the treatment, cells were collected and pellets were suspended in chilled cell lysis buffer. Colorimetric assay kits were used to analyze the activities of caspase-3 and caspase-9 (BioVision, Milpitas, CA, ...
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Positive nuclear BAP1 immunostaining helps differentiate non- small cell lung carcinomas from malignant mesothelioma
... renal cell carcinoma and other malignancies, causing a condition that we named “BAP1 cancer syndrome” ...regulate cell cycle, differentiation, apoptosis, gluconeogenesis, and the DNA damage response [18, ...
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Original Article Downregulation of ALDH1A1 expression in non-small cell lung carcinomas – its clinicopathologic and biological significance
... Other studies have found that ALDH1A1 expres- sion was not detected in 40% (12/30) to 56.1% (38/66) of NSCLCs [19, 20], and in 35% (7/20) of lung ADCs [20]. Among lung ADCs, its level was reported to be lower in invasive ...
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Lung cancer cytology: potential pitfalls- a review
... squamous cell carcinomas, adenocarcinomas, small cell carcinomas, and large cell ...mous cell carcinoma, adenocarcinoma, and large cell carcinomas are very ...
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Genome-wide DNA methylation profiling of non-small cell lung carcinomas
... Figure 2 Global analysis of DNA methylation patterns in non-small cell carcinoma. (A) Correlation between experimental replicates. Each point represents the raw methylation signal (mean coverage in ...
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CD10/NEP in non small cell lung carcinomas Relationship to cellular proliferation
... The cell surface metalloproteinase CD10/neutral endopeptidase ...of small cell carcinomas of the lung (SCLC) and normal fetal bronchial epithelium, we evaluated the ...
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Prognosis of ampullary cancer based on immunohistochemical type and expression of osteopontin
... advanced non-small cell lung cancer [15], laryngeal and hypopharyngeal carcinomas [16], hepatocellular carcinoma [17], colorectal cancer [18], idiopathic pulmonary hypertension [19], upper ...
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Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
... are non-specific and depend on the organ of origin and on the extension and aggressiveness of the ...neuroendocrine carcinomas (NECs) and well-differentiated neuroendocrine tumours ...include small ...
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Novel viruses: Update on the significance of papillomavirus infections in cats
... If PV-induced cell changes are not present, there are other methods available to investigate a potential PV aetiology of a lesion. Determining whether or not a lesion was caused by a PV can have clinical ...
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Crizotinib in non small cell lung cancer
... metastatic non-small cells lung cancer ...The small molecule Crizotinib is a selec- tive inhibitor of the receptor tyrosine kinase ALK (anaplastic lymphoma kinase) and its oncogenic variants (ALK ...
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Vaccines in Non Small Cell Lung Cancer
... Programmed death-1 (PD-1) protein is a T-cell receptor that interacts with 2 ligands, PD-L1 and PD-L2 ex- pressed by tumor cells, stromal cells, or both where an immunosuppressive action is produced [47]. The ...
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