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Non-Small-Cell Lung

Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

... in non- small cell lung cancer (NSCLC) remain ...in lung cancer tissues compared with normal lung ...NSCLC cell lines, A549 and 95D by RNA ...inhibited cell growth ...

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Cell-free DNA in non-small cell lung cancer

Cell-free DNA in non-small cell lung cancer

... early-stage non-small cell lung can- cer ...of non-small cell lung cancer have revealed molecular information used for systemic can- cer therapy targeting ...

7

FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

... Case presentation: We report on a 75-year-old man on nivolumab treatment for metastatic non-small cell lung cancer. He had undergone right lower lobectomy for lung adenocarcinoma in the ...

5

Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

... of lung cancer; unfortunately, the incidence and mortality of lung cancer is still on the rise, especially non-small cell lung cancer (NSCLC), which makes up 80 % of lung ...

9

Emerging therapies for non-small cell lung cancer

Emerging therapies for non-small cell lung cancer

... T cell (CAR-T) have been accelerated in hematological malignancies especially for CD19-targeted CAR-T-cell therapy in leukemia [214– ...regarding lung cancer have been initiated including ...

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Cetuximab and biomarkers in non-small-cell lung carcinoma

Cetuximab and biomarkers in non-small-cell lung carcinoma

... In non-small-cell lung cancer (NSCLC), as in several other cancer types, the epidermal growth factor receptor (EGFR) and its downstream signaling components represent a key axis that has been ...

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Surgical treatment in non small cell lung cancer with pulmonary oligometastasis

Surgical treatment in non small cell lung cancer with pulmonary oligometastasis

... Primary lung cancer is one of the most common malig- nant tumors and is still the leading cause of cancer- related death in many countries [1, ...of lung cancer is increasing every year, and mortality is ...

5

Vaccines in Non Small Cell Lung Cancer

Vaccines in Non Small Cell Lung Cancer

... 80%. Non-small cell lung cancer stage IIIB and IV patients were enrolled between 2000 and 2002 by centers of Canada and the United Kingdom, including a total of 171 ...a non-significant ...

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Therapeutic vaccines in non-small cell lung cancer

Therapeutic vaccines in non-small cell lung cancer

... Abstract: Non-small cell lung cancer (NSCLC) unfortunately carries a very poor ...allogeneic cell vaccine that decreases transforming growth factor (TGF-β) in the tumor ...

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Crizotinib in non small cell lung cancer

Crizotinib in non small cell lung cancer

... [16] Camidge, D.R., Bang, Y.J, Kwak, E.L, Iafrate, A.J., Va- rella-Garcia, M., Fox, S.B., Riely, G.J., Solomon, B., Ou, S.H., Kim, D.W., Salgia, R., Fidias, P., Engelman, J.A., Gandhi, L., Jänne, P.A., Costa, D.B., ...

5

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer

... Figure 7 Preclinical therapeutic efficacy of anti-PDPN NZ-1-IT in in vitro and in vivo SqNSCLC models. In vitro cytotoxicity of NZ-1-IT against (A) non-squamous A549 and (B) squamous H226 cell lines was ...

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Gefitinib for advanced non small cell lung cancer

Gefitinib for advanced non small cell lung cancer

... advanced lung cancer do not live longer when treated with gefitinib when compared with no other treatment or ...whose lung cancer has worsened after initial therapy, gefitinib may prolong the time before ...

270

Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment

Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment

... in cell cycle studies and increased apoptosis rates in A549 ...A549 cell proliferation, invasion, and metastasis by regulating the expression of other ...

10

Prognostic value of metformin for non small cell lung cancer patients with diabetes

Prognostic value of metformin for non small cell lung cancer patients with diabetes

... represents about 80% of all lung cancers diagnosed [1]. Most NSCLC patients already present with advanced stages at initial diagnosis, metastasis, and early relapse. Moreover, the prognosis of NSCLC remains ...

5

Overall  survival of driver mutation-negative non-small cell lung cancer patients with COPD under chemotherapy compared to non-COPD non-small cell lung cancer patients

Overall survival of driver mutation-negative non-small cell lung cancer patients with COPD under chemotherapy compared to non-COPD non-small cell lung cancer patients

... that lung cancer with COPD is a different phenotype, which shows a more aggressive course compared to non-COPD lung ...with lung cancer ...

8

Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

... Primary lung carcinomas have been classified into small cell lung carcinoma (SCLC) and non-small cell lung carcinoma ...squamous cell carcinoma (20-30%) and ...

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Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

... Twelve up-regulated genes were identified from 7 comparisons of 5 studies in the Oncomine database when comparing cancer tissue to the normal lung tissue of the non-small cell lung ...

8

An adherent subline of a unique small cell lung cancer cell line downregulates antigens of the neural cell adhesion molecule

An adherent subline of a unique small cell lung cancer cell line downregulates antigens of the neural cell adhesion molecule

... Small-cell lung cancer (SCLC) lines are distinguished from non-small-cell lung cancer (NSCLC) lines by their growth in floating aggregates, in contrast to the adherent ...

8

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and Therapy

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and Therapy

... inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells. 1005[r] ...

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ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

... various lung cancer cell lines as A427, A549 and H322, HTB171 and also in HeLa cervix cancer ...H358 lung cancer cells however expressed ZAR1 ...the lung (set 100%), but relatively low ...

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