noncoding RNA (ncRNA)
Induction of long noncoding RNA MALAT1 in hypoxic mice
... One of the most amazing outcomes of the high-throughput sequencing era is the discovery that approximately 75% of the genome is transcribed and that there might be approximately as many noncoding (nc) RNAs as ...
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Multiplicity in Long Noncoding RNA in Living Cells
... long noncoding RNA transcribed from the promoter region of ...long noncoding RNAs transcribed from the promoter region of CCND1 and are induced by ...long noncoding RNAs bind to RNA ...
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CRISPR Interference of a Clonally Variant GC Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum
... ABSTRACT The human malaria parasite Plasmodium falciparum uses mutually exclu- sive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of ...
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Long noncoding RNA expression profiles in sub lethal heat treated hepatoma carcinoma cells
... Long noncoding RNA (lncRNA) is generally defined as a transcript larger than 200 nucleotides that lacks protein-coding functions. Recently, lncRNAs have been shown to have critical regulatory roles in ...
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Next Generation Sequencing Reveals HIV 1 Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4+ T Cell Line
... several noncoding RNA species in HIV-infected cells that were differentially expressed ...these noncoding RNAs and their rel- evance to infection remains ...One noncoding RNA of ...
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Long noncoding RNA dysregulation in ischemic heart failure
... Total RNA from tissues was extracted using TRIzol (Life Technologies, Thermo Fisher Scientific ...Long noncoding RNA expression profiles were measured using the disease-related human lncRNA Profiler ...
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Identification of a three-long noncoding RNA prognostic model involved competitive endogenous RNA in kidney renal clear cell carcinoma
... Long noncoding RNA (lncRNA), broadly defined as noncoding RNA molecules longer than 200 nucleotides, has gained emerging attention in cancer biology due to their direct and indirect regulatory ...
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A Unique cis Encoded Small Noncoding RNA Is Regulating Legionella pneumophila Hfq Expression in a Life Cycle Dependent Manner
... small RNA named Anti-hfq that is transcribed antisense of the hfq transcript and overlaps its 5= untranslated ...small noncoding RNA (sRNA) and hfq mRNA are bound and stabilized by the Hfq protein, ...
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The multidimensional mechanisms of long noncoding RNA function
... lncRNAs as modulators of proteins and enzyme cofactors In most of the known examples, the detailed mecha- nisms by which lncRNAs enhance or inhibit the activity of proteins is not completely understood, but are prob- ...
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Long Noncoding RNA: Recent Updates in Atherosclerosis
... Cellular lipid mechanism especially in foam cells is an important issue in atherosclerosis progress. Hu et al. find that lncRNA is a novel regulator in cholesterol metabolism and inflammation. Through microarray ...
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Long noncoding RNA SNHG6 mainly functions as a competing endogenous RNA in human tumors
... With technical progress in sequencing technologies, an increasing number of noncoding RNAs (ncRNAs) have been discovered in the last several years. Long ncRNA (lncRNA), > 200 nucleotides in length, has been ...
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abd-A Regulation by the iab-8 Noncoding RNA
... XIST RNA, involved in mammalian X chromosome inactivation [30] (A recent report suggests that the XIST RNA can also work in trans ...in RNA- directed DNA methylation in Arabidopsis ...iab-8 ...
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Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation
... the noncoding regions of mammalian genomes have been found to be transcribed to generate noncoding RNAs (ncRNAs), resulting in intense interest in their biological ...6S RNA, first described as a ...
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A New Noncoding RNA Arranges Bacterial Chromosome Organization
... by RNA IP followed by microarray analysis (RIP-Chip) assays of the nucleoid-associated HU protein (7). In this paper, we termed it as nucleoid-associated ncRNA (naRNA). REP elements in the enterobacterial genomes, ...
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Synthetic Regulation of Eukaryotic Gene Expression by Noncoding RNA
... described (Win and Smolke, 2008a). Other classes of riboswitches can also be potentially employed to regulate tTA levels (Babiskin and Smolke, 2011b; Liang et al., 2011). Further, with an ever-expanding set of RNA ...
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Expression of the Antisense-to-Latency Transcript Long Noncoding RNA in Kaposi's Sarcoma-Associated Herpesvirus
... As the name suggests, ALT lies on the opposite strand of the latency (Lat) transcripts (11, 30, 66), completely overlapping most of them (Fig. 3). In addition, ALT is on the same strand and is coterminal with a ...
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Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
... Participants and diagnostic groups. According to the Brazilian Ministry of Health (BMH) guidelines, the screen to detect LTBI among recent contacts comprises a clinical evaluation by a physician specializing in pulmonary ...
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The interplay between m6A RNA methylation and noncoding RNA in cancer
... antisense RNA of GAS5, and its downregulation is closely related to the TNM stage, lymph node metastasis, and prognosis of tu- mors, such as NSCLC and liver cancer [104, ...
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Adenovirus VA1 Noncoding RNA Can Inhibit Small Interfering RNA and MicroRNA Biogenesis
... 63-nt RNA, transcribed under the control of RNA polymerase III (Pol III), that is predicted to be identical to pre-miR-30 except that the 2-nt 3 ⬘ overhang is changed from 5 ⬘ -GC-3 ⬘ to 5 ⬘ - UU-3 ⬘ to ...
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The Long Noncoding RNA HEAL Regulates HIV 1 Replication through Epigenetic Regulation of the HIV 1 Promoter
... Long noncoding RNAs (lncRNAs, ⬎ 200 nucleotides) are increasingly recognized to play important roles in ...the RNA-binding protein FUS, which facilitates HIV replication through at least two mechanisms: (i) ...
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