Normal human bronchial epithelial cell
Original Article Down-regulation of microRNA-539 promotes tumor growth and invasion through regulating FSCN1 expression in non-small cell lung cancer
... NSCLC cell lines as compared with the normal human bronchial epithelial cell ...repressed cell proliferation, migration/inva- sion in vitro, and tumor growth in xenograft ...
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Overexpression of lncRNA HOXA11-AS promotes cell epithelial–mesenchymal transition by repressing miR-200b in non-small cell lung cancer
... three human NSCLC cells A549, H1299, 95D and a normal human bronchial epithelial cell 16HBE, the results discovered that lncRNA HOXA11-AS expression levels was higher compared ...
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miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins
... SCLC cell lines compared with that in the normal human bronchial epithelial cell line 16-HBE (ATCC), and the expression of miR-216a-5p in H69 cells was higher than that in H446 ...
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Expression of Notch-1 and its clinical significance in different histological subtypes of human lung adenocarcinoma
... LAD cell lines or tissues was significantly lower than that in normal human bronchial epithelial cell line (16HBE) or nontumor tissues (P < ...
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Mechanical compression attenuates normal human bronchial epithelial wound healing
... An interesting observation is that EGF media content decreased as a result of a scrape wound, mechanical com- pression, and even more so when both injury types were applied. Puddicombe and colleagues [23] have demon- ...
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Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells
... tiation media containing 50% DMEM in BEGM with the same supplements as above but lacking triiodothyronine and with a final retinoic acid concentration of 50 nM (all- trans retinoic acid; Sigma, ST. Louis, MO, USA). HBECs ...
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Regional heterogeneity in response of airway epithelial cells to cigarette smoke
... airway epithelial cells from different sites in the lungs have not been fully ...Methods: Human small airway epithelial cells (SAECs) and normal human bronchial epithelial ...
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Original Article miR-106a promotes growth and metastasis of non-small cell lung cancer by targeting PTEN
... cer cell lines A549, H1299, and H460 was sig- nificantly increased compared with that in human normal bronchial epithelial cell line 16HBE cells (Figure 1B, P < ...NSCLC ...
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Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients
... of epithelial cells by epithelial-mesenchymal transition (EMT) induced by cigarette smoking ...EMT, epithelial cells lose their typical cell-cell junctions and cell polarity and ...
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Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells
... NHBE cell membranes reduced the number of infected cells by each of the evaluated recombinant viruses, although MBCD at low con- centration had a larger inhibitory effect on the infectivity of the FIG 3 Copatching ...
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<p>Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells</p>
... The human microvascular endothelial cells HMVEC, NSCLC cell lines A549 (adenocarcinoma), H1650 (adeno- carcinoma), SPCA-1 (adenocarcinoma), and the normal lung bronchial epithelial ...
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Stimulatory effect of inflammatory cytokines on alpha 1 antichymotrypsin expression in human lung derived epithelial cells
... lung-derived epithelial cells are capable of synthesizing high levels of alpha ...In normal bronchial epithelial cells, as well as in the HTB55 human adenocarcinoma cell line, ...
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Human basonuclin 2 up-regulates a cascade set of interferon-stimulated genes with anti-cancerous properties in a lung cancer model
... adenocarcinoma cell line A549 compared to the human normal bronchial epithelial cell line BEAS-2B, as well as in lung tumor tissue compared to non-tumor ...
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Clustered MicroRNAs of the Epstein-Barr Virus Cooperatively Downregulate an Epithelial Cell-Specific Metastasis Suppressor
... Via unbiased screening under physiological conditions, in combination with miRNA target prediction, NDRG1 was identi- fied as a direct target of BART miRNAs in EBV-infected epithelial cells. We found that a ...
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The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer
... the bronchial airway epithelium in individuals at risk for lung ...the bronchial brushing specimens of risk-stratified individuals (Table 1 and Supplemental Table 1; supplemental material available online ...
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ajplung.00020.2019.pdf
... the cell lysate and medium over 4 logs ...E: normal subjects were studied after an overnight fast for fraction of exhaled NO (F ENO ) analysis before and after airway clearance vest treatment: 10 Hz, 10 cm ...
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Uptake of DNA by cancer cells without a transfection reagent
... not normal liver cells can take large naked DNA frag- ments (compared with oligonucleotides which are nor- mally less than 20 base pairs and considered small) without the aid of either viral proteins or liposome/ ...
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S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureusdetection
... of human keratinocytes with certain bacteria ...the human lung epithelial cell lines we sought to determine if the level of expression depends on the activation status of the ...both, ...
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A cost effective technique for generating preservable biomass smoke extract and measuring its effect on cell receptor expression in human bronchial epithelial cells
... on human bron- chial epithelial cell expression of platelet-activating factor re- ceptor (PAFR), a G-protein-coupled receptor (GPCR), and an established marker of cigarette smoke exposure ...
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Original Article FOXK2 is highly expressed in gastric carcinoma, and facilitates cells proliferation through transcriptional inhibition of CHEK2 and promotes metastasis
... that tumor size (≥3 cm, p < 0.001), advanced tumor stage (p < 0.001), metastasis (p < 0.001) and high FOXK2 expression (p=0.005) were associated with overall survival (OS) (Table 2). Moreover, we performed ...
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