Notch 1 signaling pathway
Metastasis-associated lung adenocarcinoma transcript 1 promotes the proliferation of chondro­sarcoma cell via activating Notch-1 signaling pathway
... and Notch-1 signal- ing pathway in chondrosarcoma, we detected the expression of MALAT-1 and Notch-1, Hes-1, Hey-1, and Hey-2 in chondrosarcoma cells (CH2879, L835, ...
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Original Article High expression of Notch 1 with cognitive impairment in a rat model of type 2 diabetes mellitus
... the Notch 1 signaling pathway in cognitive impairment with hip- pocampal dendritic structure damage in a rat model of type 2 diabetes mellitus ...expressing Notch 1 were observed ...
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Non-small-cell lung carcinoma: role of the Notch signaling pathway
... either Notch-1 or Notch-2 found in a portion of SCCs of the lung may reflect some adaptive responses to certain microenvironmental conditions rather than being the driver of this malignancy as a ...
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New Capabilities of the Notch Signaling Pathway
... the alignment point and the end of the trace. Solid line indicates the median of the normalized promoter activity, light shaded areas show standard error of the mean, and the light gray shaded area indicates the standard ...
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CAF 1 promotes Notch signaling through epigenetic control of target gene expression during Drosophila development
... activate Notch target gene transcription with the assistance of Su(H) and co-activator Mastermind (Mam) (Bray, 2006; Artavanis-Tsakonas and Muskavitch, ...primary Notch signaling, the presence of a ...
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The Logic of Receptor Ligand Interactions in the Notch Signaling Pathway
... Figure 2.9 (previous page): Protocol and data analysis pipeline for availability assay. (A) Test cells were induced for 48 hours with varying concentrations of 4-epiTc. On the day of the experiment, the cells are ...
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Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia?
... with Notch pathway mutant alleles and ...of Notch on chromosome ...of Notch on chromosome ...regulated signaling of pathways and normal kidney development and function, whereas loss of ...
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Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice
... The Notch signaling pathway is involved in cell fate determination and has been implicated in proximal-distal patterning in the mammalian ...of Notch signaling in renal collecting duct ...
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Differential Effects of Drosophila Mastermind on Asymmetric Cell Fate Specification and Neuroblast Formation
... embryo, Notch signaling participates in the pathway that mediates asymmetric fate specification to daughters of secondary neuronal precursor ...cord, Notch signaling specifies sib fate ...
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Original Article Regulation of calcium pump through Notch/Jagged/Hes signaling pathway in canine model of chronic atrial fibrillation
... of Notch-1 and its down- stream target genes including Hes1, Jagged1, and SERCA2a in the atrial myocardium of canines with chronic ...between Notch-1/Hes1/Jagged1 and the SERCA2a calcium pump ...
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Targeting Wnt pathway in mantle cell lymphoma-initiating cells
... Wnt, Notch, and Hedgehog signaling pathways, which are re- quired for their growth and self-renewal ...Wnt signaling in MCL tumorigen- esis [12 – 14]. The Wnt signaling pathway ...
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Original Article Pathway analysis of esophageal squamous cell carcinoma using iTRAQ-based quantitative proteomic approach
... Wnt signaling pathway played a very important role in the development of ...(KEGG) pathway database were matched against by those proteins’ ...and signaling pathways could help elucidate the ...
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Identification of Drosophila Genes Modulating Janus Kinase/Signal Transducer and Activator of Transcription Signal Transduction
... all signaling pathways required during development, the JAK/STAT cascade does not function in isolation, and cross-talk between multiple interacting loci is likely to be involved in generating developmental ...
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Bioinformatics analysis of differentially expressed genes in rotator cuff tear patients using microarray data
... calcium signaling pathway is also linked with the activation of neuromuscular connections, and calcium-ion influx through voltage-gated calcium channels regulates the neuron’s responsiveness to ...
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Emergence of traveling waves in the zebrafish segmentation clock
... Fgf signaling, abolished the intrinsic traveling waves as well as the marginal her1 oscillation at early stages ...Fgf signaling would induce her1 oscillation in the ...Fgf signaling is that Fgf ...
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No Evidence for an Association Between Common Nonsynonymous Polymorphisms in Delta and Bristle Number Variation in Natural and Laboratory Populations of Drosophila melanogaster
... the Notch signaling pathway contribute to standing variation in sternopleural and/or abdominal bristle number in Drosophila melanogaster, for both a large cohort of wild-caught flies and previously ...
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Mechanisms of Notch signaling: a simple logic deployed in time and space
... of signaling trans-complexes, discriminating them from inactive cis- complexes, are important challenges that remain to be ...synthetic Notch receptors (synNotch) in which both the input and output domains ...
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Notch signaling in the development of the inner ear
... The Alternating Mosaic of Hair Cells and Supporting Cells Suggests a Simple Lateral Inhibition Model for Genesis of Spatial Pattern. The ratio o f hair cells to supporting cells in a mature sensory patch is variable from ...
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Notch: a mastermind of vascular morphogenesis
... product that can influence the sensitivity of HSCs to HIV-1 infection (see the related article beginning on page 473). Strikingly, p21 appears to alter the fate of nuclear HIV-1 DNA, promoting the formation ...
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Notch signaling deregulation in multiple myeloma: A rational molecular target
... reported, Notch signaling alterations described in MM result in an increased expression of Notch pathway members including receptors and ligands ...of Notch signaling in ...
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