NPH insulin
Insulin glargine compared to neutral protamine Hagedorn (NPH) insulin in patients with type-2 diabetes uncontrolled with oral anti-diabetic agents alone in Hong Kong: a cost-effectiveness analysis
... inadequate insulin production and action resulting in ...and insulin supplement will be required in the majority of patients as pancreatic beta-cell function deteriorates over time ...basal insulin ...
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Quality of life of patients with type 1 diabetes using insulin analoge glargine compared to NPH insulin : a systematic review and policy implications
... versus NPH insulin would promote better QoL, as GLA insulin could lead to a decrease in the episodes of hypoglycemia and would also cause less discomfort to ...versus NPH insulins [14, ...
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Health economic evaluations comparing insulin glargine with NPH insulin in patients with type 1 diabetes: a systematic review
... to NPH in the study from Brändle et ...for insulin injection and disposables for blood glucose self-monitoring; (iii) utility decrements following the concept of fear of hypoglycaemia were applied; (iv) ...
13
Glargine and detemir: Safety and efficacy profiles of the long-acting basal insulin analogs
... basal insulin analogs, glargine and detemir, make them a better choice than NPH for basal insulin ...which insulin has a flatter pharmacodynamic profile and longer duration of ...with ...
11
Evaluating the cost-effectiveness of insulin detemir versus neutral protamine Hagedorn insulin in patients with type 1 or type 2 diabetes in the UK using a short-term modeling approach
... PSA yielded similar outcomes to the deterministic base-case analyses with incremental quality-adjusted life expectancy of 0.101 QALYs (standard deviation [SD] 0.038 QALYs) and incremental costs of GBP 59 (SD GBP 45) in ...
10
Insulin glargine in a Brazilian state : should the government disinvest? an assessment based on a systematic review
... the insulin analogue (Insulin glargine) have been growing appreciably in the State of Minas Gerais in Brazil, averaging 291% per year in recent ...between insulin glargine and neutral protamine ...
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s-0028-1095181.pdf
... either insulin glargine or neutral protamine Hagedorn (NPH) ...used insulin glargine. A total of 13 women used insulin glargine during the first ...used NPH insulin and ...
6
Insulin detemir for the treatment of obese patients with type 2 diabetes
... with insulin detemir versus NPH insulin, and it is reasonable to expect that this may result in less defensive eating, decreased weight gain with insulin detemir is not completely explained by ...
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Treatment satisfaction and quality-of-life between type 2 diabetes patients initiating long- vs. intermediate-acting basal insulin therapy in combination with oral hypoglycemic agents – a randomized, prospective, crossover, open clinical trial
... with insulin glargine were ...for insulin glargine in comparison to NPH in- sulin (RR, ...the NPH insulin group (RR, ...receiving NPH insulin in comparison to ...
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Critical appraisal of the safety and efficacy of insulin detemir in glycemic control and cardiovascular risk management in diabetics
... the insulin detemir clinical trials program was of reduced weight gain versus both NPH insulin and insulin glargine (Tables 1, 2, and ...diabetes, insulin detemir has tended to be ...
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The clinical effectiveness of insulin glargine in patients with type 1 diabetes in Brazil : findings and implications
... of NPH insulin and insulin glargine were compared using the T test for paired ...using insulin glargine, Chi-square test of Pearson was conducted for categorical variables and an analysis of ...
15
Biphasic insulin Aspart 30 vs. NPH plus regular human insulin in type 2 diabetes patients; a cost-effectiveness study
... among NPH/Reg ...human insulin from the subcutaneous tissue which leads to a delayed peak two to three hours after injection ...basal NPH insulin vary and its duration of action is shorter ...
9
Diabetes Treatment, Part 3: Insulin and Incretins
... regular insulin yields neutral protamine Hagedorn (NPH) ...of NPH insulin is typically in 2–4 hours, with a peak of activity in 4–10 hours and an effective duration of 10–16 ...action, ...
5
Nephrotoxicity in Recipients of Vancomycin vs. Vancomycin with Vitamin C
... Long-acting insulin plays an important role for maintaining basal insulin levels in patients with ...T1DM. Insulin glargine is a long-acting insulin analog and isa moreuseful basal ...
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A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus
... both insulin glar- gine and NPH insulin ...that insulin glar- gine and NPH insulin may be associated with a lower frequency of symptomatic and severe hypoglycaemia in Chinese ...
11
Management of diabetes across the course of disease: minimizing obesity-associated complications
... of insulin detemir in the central nervous system may also contribute to its decreased risk for weight gain versus NPH insulin and insulin ...of insulin detemir during ...
17
Changing basal insulin from NPH to detemir or glargine in patients with type 1 diabetes and a history of severe hypoglycemia
... For these reasons, governmental authorities and/or other payers (eg, insurance companies) in several industrialized countries around the globe (eg, Sweden, Finland, Denmark, UK, US, Australia, Canada, Germany, Spain, ...
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A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design
... human NPH insulin and human regular insulin (Insulatard W /Actrapid W ), in random ...of insulin are adjusted according to individual patient need at the discretion of the ...of insulin ...
7
Detemir as a once-daily basal insulin in type 2 diabetes
... Following 26 weeks of treatment, significant reductions in A1C from baseline were observed in both groups (detemir 0.2%; P = 0.004 and NPH 0.4%; P , 0.001). The number of injections of detemir did not ...
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The role of insulin detemir in overweight type 2 diabetes management
... of insulin therapy in the management of type 2 diabetes requires the use of an effective insulin formulation that is both safe and acceptable to patients and physicians ...long-acting insulin ...
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