nuclear factor-erythroid 2-related factor
Nuclear factor erythroid 2 – related factor 2 and its relationship with cellular response in nickel exposure: a systems biology analysis
... ectly related nickel-induced carcinogenesis) and induce chemokine and cytokine gene expression (nickel-driven correlated pathway to immune response) [7, ...the Nuclear factor-erythroid ...
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Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking
... Nuclear factor erythroid 2-related factor 2 (Nrf2), also known as NFE2L2, is ubiquitously expressed at high concentrations in various human organs including the ...
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Nuclear factor erythroid 2 related factor 2 is a critical target for the treatment of glucocorticoid resistant lupus nephritis
... NF, nuclear factor; NQO1, NAD(P)H:- quinone oxidoreductase 1; Nrf2, nuclear factor erythroid 2-related factor 2; nRNP, nuclear ribonucleoprotein; PAS, ...
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The Effect of Nimodipine on Nuclear Factor Erythroid-2-Related Factor 2 (Nrf2) Activation in Neuron Cell Line SH-SY5Y Culture Exposed By Chronic Hyperglycemia
... [8]. Nuclear factor erythroid-2- related factor 2 (Nrf2) is a transcription factor that functions to regulate genes that encode antioxidants and detoxification ...
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Neuroprotective effect of dimethyl fumarate in stroke: The role of nuclear factor erythroid 2-related factor 2
... Nuclear factor erythroid 2-related factor 2 (Nrf2) is one of the most important endogenous protective factors against oxidative ...
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Pathophysiological processes in multiple sclerosis: focus on nuclear factor erythroid-2-related factor 2 and emerging pathways
... Abstract: Multiple sclerosis (MS) is a disease of the central nervous system that is characterized by the demyelination of neuronal axons. Four different patterns of demyelination have been described, showing the ...
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Nuclear Factor Erythroid 2 Related Factor 2 and Heme Oxygenase 1 Protein Expression and Clinicopathological Features in Glioblastoma
... pathways related to oxidative stress is likely to become potential targets for cancer ...transcription factor and plays a critical coordinator as regulating the re- dox balance and protecting cells against ...
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Protective effects of nuclear factor erythroid 2-related factor 2 on whole body heat stress-induced oxidative damage in the mouse testis
... Most mammal testes suspend in a scrotum outside the body cavity and are more susceptible to heat than other organs [2,16]. Scrotal temperature above the normal range can disrupt spermatogenesis and increase rates of sub ...
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Adoptive Transfer of Heme Oxygenase-1 (HO-1)-Modified Macrophages Rescues the Nuclear Factor Erythroid 2-Related Factor (Nrf2) Antiinflammatory Phenotype in Liver Ischemia/Reperfusion Injury
... Adoptive transfer of Ad-HO-1 BMMs induced Akt activation and enhanced antiapoptotic gene expression in Nrf2- deficient livers, accompanied by de- creased frequency of apoptotic cells. In marked contrast, Nrf2 deficiency ...
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Changes in Monocyte Chemoattractive Protein, Nuclear Respiratory Factor 2, B-Cell Leukemia/Lymphoma 2 and Cholinesterase in Serum of Autistic Children
... the nuclear factor erythroid 2-related factor 2 ...transcription factor Nrf2 regulates cellular resistance to oxidants via controlling the expression of antioxidant ...
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Impact of chromium histidinate on high fat diet induced obesity in rats
... Nuclear factor erythroid 2-related factor 2 controls the antioxidant response element (ARE)-dependent gene regulation in response to oxidative ...subsequent nuclear ...
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Oxidative stress in sepsis: a redox redux
... that nuclear factor-erythroid 2–related factor 2 (Nrf2, also known as Nfe2l2), which encodes a basic region–leucine zipper transcription fac- tor, is a key regulator of ...
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Original Article Xylaria nigripes protects mice against cerebral ischemic injury by activating Nrf2/HO-1 pathway
... 3, nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), GFAP, NGFR, BDNF, NTRK1, and NTRK2 expression were assessed in the ischemic mouse ...
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An Update on the Role of Nrf2 and its Activators in Diseases Associated with Oxidative Stress
... diseases. Nuclear factor erythroid-2-related factor 2 is a master transcription factor belonging to the leucine zipper ...of nuclear factor ...
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Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments
... This clustering analysis suggests that different skin care needs depend on the naturally occurring single genetic vari- ants present in each one of the genetic clusters. For example, cluster 8 shows the worst combination ...
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Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells
... the nuclear factor erythroid-2-related factor 2 (Nrf2) pathway and synthesis of heme oxygenase (HO-1), as well as to mitigate lipopolysaccharide (LPS)-induced nitric oxide ...
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Inhibitory effect of phytol on cellular senescence
... necrosis factor-alpha), IL6 (interleukin 6), IL8 (interleukin 8), and COX2 (cyclooxygenase ...(nuclear factor erythroid 2-related factor 2), HO-1 (heme oxygenase ...
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Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2/hemoxygenase-1 pathway by altering the balance of M1/M2 macrophages
... for 2 min, followed by 4 % paraformaldehyde dis- solved in PBS for 5 ...vessel; 2, cellular infil- tration plus demyelination in immediate proximity to the vessel; 3, cellular infiltration and demyelination ...
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Radix puerariae extracts ameliorate paraquat induced pulmonary fibrosis by attenuating follistatin like 1 and nuclear factor erythroid 2p45 related factor 2 signalling pathways through downregulation of miRNA 21 expression
... For RNA isolation, lung tissues were frozen in liquid nitro- gen and stored in a −80 °C freezer until use. Total RNA was extracted from frozen lung tissue (left lung) with TRI- zol reagent and amplified with a PCR ...
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Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis
... fumarate, nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2), laquinimod, and teriflunomide linked to MS, experimental autoimmune encephalomyelitis (EAE), immune ...
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