nucleus accumbens
The Effect of Oxytocin on Food Intake in the Nucleus Accumbens Core
... Abstract: Objective: In this experiment, we mainly investigated whether oxytocin (OT) acts on the Nucleus Accumbens Core (NAc) to regulate the feeding behavior of rats. Methods: Immunohistochemical ...
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Cellular and chemical dynamics within the nucleus accumbens during reward-related learning and decision making
... An organism’s ability to obtain food in natural environments often requires considerable expenditures of time and energy that must be correctly evaluated to optimize decision making strategies. A fundamental cost in all ...
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Ethanol-induced locomotor sensitization: NPY signaling and histone acetylation in the nucleus accumbens and striatum of DBA_2J mice
... the nucleus accumbens core attenuates the expression of locomotor sensitization (Hayes, Fee et ...the nucleus accumbens and striatum (Fee, Knapp et ...
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Basolateral amygdala regulation of cellular and chemical signals within the nucleus accumbens during conditioned reward-seeking
... The nucleus accumbens (NAc) has long been described as an important neural substrate for reward processing, particularly in mediating the effects of motivationally relevant stimuli on goal-directed ...
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Behavioral flexibility is increased by optogenetic inhibition of neurons in the nucleus accumbens shell during specific time segments
... The nucleus accumbens may play an important role in behavioral flexibility, representing learned stimulus – reward associations in neural activity during re- sponse selection and learning from ...of ...
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Glutamate Receptors in Nucleus Accumbens Can Modulate Canabinoid-Induced Antinociception in Rat’s Basolateral Amygdala
... Figure 1. Effects of administration of different doses of AP5, a NMDA receptor antagonist, into the nucleus accumbens (NAc) on antinociception induced by WIN55,212-2 microinjected into the basolateral ...
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Acute and Chronic Tramadol Treatment Impresses Tyrosine Kinase B (Trk-B) Receptor in the Amygdala and Nucleus Accumbens
... Background: Misuse of opioid painkillers such as tramadol has in- creased in the world. These painkillers have psychological side effects such as dependence and tolerance. Moreover, the role of Tyrosine-Ki- nase B ...
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Effect of Aqueous Extract of Phoenix dactylifera Pollen on Dopamine System of Nucleus Accumbens in Male Rats
... Sexually experienced male rats anesthetized with ketamine hydrochloride (100 mg/100g I.P.) and xylazine (10 mg/100g I.P.) and implanted with a vertically oriented microdialysis probe into the nucleus ...
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Opposing effects of 5,7 DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli
... the nucleus accumbens (NAc) as a key component of the neural circuit underpinning LI and furthermore, this work has shown that the core and shell subregions of the NAc contribute differentially to the ...
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<p>Chronic stress increases susceptibility to food addiction by increasing the levels of DR2 and MOR in the nucleus accumbens</p>
... the nucleus accumbens shell subregion (NAc-sh), nucleus accumbens core subregion (NAc-Co), lateral hypothalamus (LH) and ventral tegmen- tal area (VTA) were microdissected on a freezing micro- ...
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The nucleus accumbens as a nexus between values and goals in goal-directed behaviour: a review and a new hypothesis
... Goal-directed behavior is a fundamental means by which animals can flexibly solve the challenges posed by variable external and internal conditions. Recently, the processes and brain mechanisms underlying such behavior ...
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Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress?
... Cannulae used for behavioral tests after microinjections were first located by measuring how far ventral ink extended directly below a microinjection cannula, and identifying the midway point on the vertical line between ...
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Effect on the expression of drd2 and drd3 after neonatal lesion in the lymphocytes, nucleus accumbens, hippocampus and prefrontal cortex: comparative analysis between juvenile and adult Wistar rats
... In the case of the mRNA expression in the hippocampus, no changes were observed for drd2 or drd3 . However, with regard to the accumbens core, a clear decrease in the drd2 transcript was observed in adults against ...
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Differential Effects of Voluntary Ethanol Consumption on Dopamine Output in the Nucleus Accumbens Shell of Roman High and Low Avoidance Rats: A Behavioral and Brain Microdialysis Study
... the nucleus accumbens (Acb) [33]-[35], and this effect is more robust in the medioventral shell subregion of this nucleus (AcbSh) than in the dorsolateral core (AcbC) ...
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The roles of the nucleus accumbens core, dorsomedial striatum, and dorsolateral striatum in learning : performance and extinction of Pavlovian fear conditioned responses and instrumental avoidance responses
... the nucleus accumbens core (NAc-co) plays a role in Pavlovian conditioning (Riedel, Harrington, Hall, and Macphail, 1997; Ikemoto and Panksepp, 1999; Di Chiara, 2002; Belin, Jonkman, Dickinson, Robbins, and ...
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Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat
... the nucleus accumbens, here, we studied the effect of apomorphine on PPI in D2 down-regulated ...the nucleus accumbens, with or without apomorphine ...the nucleus accumbens ...
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What lies beneath peer acceptance in adolescence? Exploring the role of Nucleus Accumbens responsivity to self-serving and vicarious rewards
... Peer relationships play an important role in adolescent social development. Adolescence is also a sensitive period for reward-related processing where Nucleus Accumbens (NAcc) shows peak levels of activity. ...
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Functional Interaction between the Shell Sub-Region of the Nucleus Accumbens and the Ventral Tegmental Area in Response to Morphine: an Electrophysiological Study
... of nucleus accumbens (NAc)-ventral tegmental area (VTA) ...the nucleus accumbens (NAcSh) neurons were employed to determine the functional contributions of the VTA to neuronal activity across ...
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Functional roles of the rat nucleus accumbens: further investigations using microinjection, lesion and electrochemical techniques
... The nucleus accumbens (N.Acc.) has been ascribed an important role in mediating locomotor activity and exploration, as well as more complex processes such as reinforcement, reward and the acquisition of ...
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Nucleus accumbens neurons encode Pavlovian approach behaviors : evidence from an autoshaping paradigm
... The ability to form and use Pavlovian associations requires the existence and cooperation of brain circuits equipped to integrate sensory and motivational information and alter motor output. The nucleus ...
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