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Null Alleles

Estimating Relatedness in the Presence of Null Alleles

Estimating Relatedness in the Presence of Null Alleles

... to null alleles cannot be resolved in this manner. Null alleles are pervasive in microsatellite markers and many studies report null alleles ...with null alleles ...

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Estimating contemporary migration rates : effect and joint inference of inbreeding, null alleles and mistyping

Estimating contemporary migration rates : effect and joint inference of inbreeding, null alleles and mistyping

... time. Null alleles were updated separately (see next section), so that acceptance rates could be tuned ...non-null alleles, a and b, and propose p ila ' = u, where u ∼ U [max(0, p ila − e p ), ...

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Nuclear retention of COL1A1 messenger RNA identifies null alleles causing mild osteogenesis imperfecta

Nuclear retention of COL1A1 messenger RNA identifies null alleles causing mild osteogenesis imperfecta

... a null allele due to a premature stop mutation in the mutant RNA ...a null allele arising from a splice donor mutation where the transcript containing the included intron was sequestered in the ...from ...

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Null Alleles in Gliadin Coding Loci and Wheat Allergenic Properties

Null Alleles in Gliadin Coding Loci and Wheat Allergenic Properties

... called null alleles that do not code any proteins at ...whether null alleles in some gliadin coding loci may decrease wheat allergenic ...containing null alleles on 1D, 1B and 6B ...

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Performing Parentage Analysis in the Presence of Inbreeding and Null Alleles

Performing Parentage Analysis in the Presence of Inbreeding and Null Alleles

... et al. 2006). These incorrect genotypes can be problematic for parentage analyses, because such genotyping errors can mis- takenly reject a true parent due to an observed lack of the shared alleles with the ...

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CRISPR induced null alleles show that Frost protects Drosophila melanogaster reproduction after cold exposure

CRISPR induced null alleles show that Frost protects Drosophila melanogaster reproduction after cold exposure

... The ability to survive and reproduce after cold exposure is important in all kingdoms of life. However, even in a sophisticated genetic model system like Drosophila melanogaster, few genes have been identified as ...

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FREQUENCIES OF NULL ALLELES AT ENZYME LOCI IN NATURAL POPULATIONS OF PONDEROSA AND RED PINE

FREQUENCIES OF NULL ALLELES AT ENZYME LOCI IN NATURAL POPULATIONS OF PONDEROSA AND RED PINE

... Ponderosa pine have much higher amounts of allozymic and polygenic phenotypic variation than red pine, yet both species have similar frequencies of null alleles.. Thus[r] ...

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An Evaluation of Evolutionary Constraints on Microsatellite Loci Using Null Alleles

An Evaluation of Evolutionary Constraints on Microsatellite Loci Using Null Alleles

... If these measures of the null series are significantly smaller or larger than those of the main series, the minimum evolutionary time of the series compared can be set to [r] ...

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Studies on alcohol dehydrogenase null alleles from natural populations of drosophila melanogaster

Studies on alcohol dehydrogenase null alleles from natural populations of drosophila melanogaster

... Genetic variation at the alcohol dehydrogenase locus in DPosophila melanogasteP in relation to environmental variation: Ethanol levels in breeding sites and allozyme frequencies.. electr[r] ...

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Patterns of spatial genetic structures in Aedes albopictus (Diptera: Culicidae) populations in China

Patterns of spatial genetic structures in Aedes albopictus (Diptera: Culicidae) populations in China

... 153 alleles were ...distinct alleles rang- ing from eight (Aealbmic9) to sixteen (ALB-TRI-6) with an average of ...of null alleles, as its estimated null allele frequency is ...of ...

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DOMINANT SUPPRESSORS OF A MUSCLE MUTANT DEFINE AN ESSENTIAL GENE OF CAENORHABDITIS ELEGANS

DOMINANT SUPPRESSORS OF A MUSCLE MUTANT DEFINE AN ESSENTIAL GENE OF CAENORHABDITIS ELEGANS

... The null phenotype of sup-11 is recessiue lethal: Null alleles of genes have been obtained by reversion of dominant “neomorphic” mutations (which result i n the acquisitio[r] ...

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Microsatellite markers for the notothenioid fish Lepidonotothen nudifrons and two congeneric species

Microsatellite markers for the notothenioid fish Lepidonotothen nudifrons and two congeneric species

... of null alleles in studies of pop- ulation genetics might be marginal compared to other factors such as the number of loci and strength of popu- lation differentiation ...

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A null deficiency allele of alpha 1 antitrypsin, QOludwigshafen, with altered tertiary structure

A null deficiency allele of alpha 1 antitrypsin, QOludwigshafen, with altered tertiary structure

... PI*QOludwigshafen, which has a base substitution in exon II, replacing isoleucine 92 in the normal sequence with an asparagine. This substitution of a polar for a nonpolar amino acid occurs in one of the alpha-helices ...

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Identification and characterisation of eight novel SERPINA1 Null mutations

Identification and characterisation of eight novel SERPINA1 Null mutations

... the Null-bearing subjects presented herein is not the main purpose of this study, we can draw some interesting ...with Null mutations should be con- sidered a subgroup at particularly high risk of emphysema ...

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Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae.

Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae.

... An ancl mutant allele failed to complement null alleles of the SAC6 and TPMl genes that encode yeast fimbrin and tropomyosin, respectively.. Taken together, the above[r] ...

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Genetic Hitchhiking and the Evolution of Reduced Genetic Activity of the Y Sex Chromosome

Genetic Hitchhiking and the Evolution of Reduced Genetic Activity of the Y Sex Chromosome

... The genetic hitchhiking model predicts that there should be selection for null alleles after deleterious mutations have been fixed on the Y chromosomes and dosage tolerance[r] ...

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ESSENTIAL GENES AND DEFICIENCIES IN THE UNC-22 IV REGION OF CAENORHABDITIS ELEGANS

ESSENTIAL GENES AND DEFICIENCIES IN THE UNC-22 IV REGION OF CAENORHABDITIS ELEGANS

... The lethal mutations will be tested for suppression by the informational suppressor, sup-7 X, to identify null alleles of the let genes (WATERSTON 1981). In addition to t[r] ...

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GENETIC CONTROL OF MALATE DEHYDROGENASE ISOZYMES IN MAIZE

GENETIC CONTROL OF MALATE DEHYDROGENASE ISOZYMES IN MAIZE

... Electrophoretically “null” alleles are found rarely at each of the three loci; in homogenates of coleoptile tissue, these usually fail to produce hybrid bands, although at least [r] ...

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SEX DETERMINATION IN THE NEMATODE C. ELEGANS: ANALYSIS OF tra-3 SUPPRESSORS AND CHARACTERIZATION OF fem GENES

SEX DETERMINATION IN THE NEMATODE C. ELEGANS: ANALYSIS OF tra-3 SUPPRESSORS AND CHARACTERIZATION OF fem GENES

... Null alleles and deficiencies of fem-3: By analogy with mutations of fem-1, it was argued that recessive fem-3 mutations causing complete feminization of XO animals [r] ...

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NULL ALLELE FREQUENCIES AT ALLOZYME LOCI IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER

NULL ALLELE FREQUENCIES AT ALLOZYME LOCI IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER

... recently reported the frequencies of null alleles at 25 allozyme loci in a wEmple of Drosophila melanogaster from North Carolina (VOELKER et al.. There was significant variat[r] ...

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