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OBSERVATIONS ON DISEASE EXPRESSION : Both virulence and

Comparison of the expression of cytokine genes in the bursal tissues of the chickens following challenge with infectious bursal disease viruses of varying virulence

Comparison of the expression of cytokine genes in the bursal tissues of the chickens following challenge with infectious bursal disease viruses of varying virulence

... These results demonstrate that the difference in the expression levels of cytokines was possibly influenced by the different degree of viral replication. However, factors influencing the timing of cytokine ...

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The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

... some observations fall below the detection ...point, observations were replaced by ...tween both infected groups of the test statistic was obtained by simulation, by randomly reshuffling the data ...

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The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

... some observations fall below the detection ...point, observations were replaced by ...tween both infected groups of the test statistic was obtained by simulation, by randomly reshuffling the data ...

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Differential Expression and Roles of Staphylococcus aureus Virulence Determinants during Colonization and Disease

Differential Expression and Roles of Staphylococcus aureus Virulence Determinants during Colonization and Disease

... Different virulence factors are required for ...study, virulence gene expression was analyzed in two ...pathogen. Expression of 23 putative S. aureus virulence determinants, ...

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Expression of Virulence Genes in Salmonella

Expression of Virulence Genes in Salmonella

... The recently completed annotation of both S. typhimurium LT2 and S.typhi genomes shows that only 6 open reading frames exist. Ahmer et al. demonstrated SPI-4 regulation by SirA, a transcriptional regulator of ...

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Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease

Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease

... Pneumococcal disease continues to account for significant morbidity and mortality ...the disease spectrum, a complete under- standing of pneumococcal behavior in vivo is ...the expression patterns of ...

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Observations of extensive gene expression differences in the cerebellum and potential relevance to Alzheimer’s disease

Observations of extensive gene expression differences in the cerebellum and potential relevance to Alzheimer’s disease

... gene expression is altered in disease it is of fundamental importance that the global distribution of gene expression levels across the disease‑free brain are understood and how differences ...

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Asthma: Eosinophil Disease, Mast Cell Disease, or Both?

Asthma: Eosinophil Disease, Mast Cell Disease, or Both?

... the disease is classified, for example, atopic, non-atopic, or ...These observations have also been made in studies looking at induced sputum, where again about 25% of steroid-naive asthmatic subjects can ...

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Virulence and pathogenesis of chytridiomycosis: a lethal disease of amphibians

Virulence and pathogenesis of chytridiomycosis: a lethal disease of amphibians

... However, both were samples from the same culture, and the P10 was frozen in liquid nitrogen until it was revived, so sample differences or effects of history during preservation seem very ...

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Condition dependent expression of virulence in a trypanosome infecting bumblebees

Condition dependent expression of virulence in a trypanosome infecting bumblebees

... run both experiments with one set of colonies and strains, this was not possible for practical ...condition-dependent virulence is indeed real, and not an experimental ...

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Regulation of bacterial virulence gene expression by the host environment

Regulation of bacterial virulence gene expression by the host environment

... control virulence gene expression in pathogens also stimulate global regulatory changes in many genes common to both pathogens and commensal ...Therefore, virulence gene expression must ...

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Expression of Hygromycin Phosphotransferase Alters Virulence of Histoplasma capsulatum

Expression of Hygromycin Phosphotransferase Alters Virulence of Histoplasma capsulatum

... reduced virulence. In a background of reduced virulence, the lethality noted in this study associated with hph expression may not be ...perturb virulence traits are ...reduced ...

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Inactivation of thyA in Staphylococcus aureus Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene Expression

Inactivation of thyA in Staphylococcus aureus Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene Expression

... In the present work, we showed for the first time that TS pro- teins of clinical TD-SCVs are inactive due to various mutations in thyA. Site-directed mutants constructed in S. aureus SH1000 and S. aureus JE2 (USA300 ...

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Determinants of Bluetongue Virus Virulence in Murine Models of Disease

Determinants of Bluetongue Virus Virulence in Murine Models of Disease

... infectious disease of ruminants that is caused by bluetongue virus ...analyzed virulence and genetic differences of (i) three BTV field strains from Italy maintained at either a low (L strains) or high (H ...

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MicroRNA Expression and Virulence in Pandemic Influenza Virus-Infected Mice

MicroRNA Expression and Virulence in Pandemic Influenza Virus-Infected Mice

... for Disease Control and Prevention, Atlanta, Georgia 4 Received 19 October 2009/Accepted 27 December 2009 The worst known H1N1 influenza pandemic in history resulted in more than 20 million deaths in 1918 and ...

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Formate Promotes Shigella Intercellular Spread and Virulence Gene Expression

Formate Promotes Shigella Intercellular Spread and Virulence Gene Expression

... The ipaJ complement plasmid (pBK24) was constructed by amplifying the ipaJ locus beginning ⬃ 400 bp upstream of the annotated ipaJ gene and ending at the ipaJ stop codon from S. flexneri DNA by PCR with primers ...

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Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle

Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle

... 2000), both of which positively influence expression of virulence- related ...tative virulence determinants of streptococci, were tran- scribed at lower levels in the absence of ...gene ...

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The Large Polymerase Protein Is Associated with the Virulence of Newcastle Disease Virus

The Large Polymerase Protein Is Associated with the Virulence of Newcastle Disease Virus

... In this study, we examined the role of internal proteins (N, P, and L) in the pathogenicity of NDV. Reverse genetics was used to exchange the N, P, or L gene between a lentogenic strain, LaSota, and a mesogenic strain, ...

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Virulence of newcastle disease virus: what is known so far?

Virulence of newcastle disease virus: what is known so far?

... NDV virulence has been examined by generating chimeric viruses in which genes were exchanged between strains of different pathotypes ...levels both in vitro and in vivo and to be slightly more virulent than ...

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H pylori iceA alleles are disease-specific virulence factors

H pylori iceA alleles are disease-specific virulence factors

... common virulence factors in both chronic gastritis and duodenal ulcer disease while iceA alleles show specificity for gastroduodenal ulcer ...

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