obstructive azoospermia
Original Article Relationship of paternal age with outcome of percutaneous epididymal sperm aspiration and testicular sperm aspiration: intracytoplasmic sperm injection with obstructive azoospermia
... Abstract: Objective: The study aimed to compare intracytoplasmic sperm injection (ICSI) outcome of patients with epididymal sperm and testicular sperm in different paternal age with obstructive azoospermia. ...
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Altered miRNA profile in testis of post-cryptorchidopexy patients with non-obstructive azoospermia
... especailly at the post-transcriptional levels [6]. MicroRNAs (miRNAs) are a series of small noncoding RNAs that nega- tively regulate gene expression after transcription [7]. Re- search has shown that miRNAs play crucial ...
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Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients
... Changes in the complex process of spermatogenesis caused by genetic background or environmental factors can lead to male infertility. Infertile men with no sperm cells in the ejaculate can father a child with the help of ...
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Microdeletion of the AZFc locus with high frequency of mosaicism 46,XY/47XYY in cases of non obstructive azoospermia in eastern population of India
... non-obstructive azoospermia (NOA) referred to the Cytogenetic and Molecular laboratory, Department of Pathology/ Lab Medicine, AIIMS-Patna for genetic ...proband. Azoospermia was defined as total ...
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A comprehensive assessment of predictors of fertility outcomes in men with non-obstructive azoospermia undergoing microdissection testicular sperm extraction
... Approximately 1% of men in the United States and 5–10% of men evaluated for infertility are azoospermic [1, 2]. It has been established that microdissection testicular sperm extraction (microTESE) allows for retrieval of ...
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X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in Han Chinese population
... Human X chromosome has higher densities of microRNAs (miRNAs) compared to the average densities on autosomes. Given that numbers of X-linked miRNAs can escape from meiotic sex chromosome inactivation (MSCI) silencing, it ...
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Cytogenetic Investigation in a Group of Ten Infertile Men with Non-Obstructive Azoospermia: First Algerian 46, XX Syndrome
... non- obstructive azoospermia or severe oligozoo- spermia is due to chromosomal abnormalities or mutations of genes involved in sex determination and spermatogenesis ...
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Spermatogonial Stem Cells Protein Identification in In Vitro Culture from Non- Obstructive Azoospermia Patient
... Dulbecco’s Modified Eagle Medium (DMEM) used with KSR significantly reduces embryonic stem cell (ESC) differentiation, growth, and maintenance of undifferentiated ESCs. Kossack et al. (8) discovered that the culture of ...
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Metabolic Fingerprinting of Seminal Plasma from Non-obstructive Azoospermia Patients: Positive Versus Negative Sperm Retrieval
... ( 1 H-NMR) in 1994. They showed the potential of application of 1 H-NMR analysis for seminal plas- ma composition. Hamamah et al. did the second study which showed the application of magnetic resonance spectroscopy ( 1 ...
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Frequency of CYP1A1 Gene Polymorphisms in Infertile Men with Non-obstructive Azoospermia
... One hundred and five infertile men with non obstructive azoospermia who had referred to Yazd Reproductive Sciences Institute were studied. One hundred and four fertile men were included in this study as ...
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Y Chromosome Microdeletions in Infertile Men with Non-obstructive Azoospermia and Severe Oligozoospermia
... non-obstructive azoospermia and severe oligozoospermia; this find- ing is consistent with previous reports ...non- obstructive azoospermic patients and one severe oligozoospermic patient in our ...
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Altered microRNA expression in patients with non-obstructive azoospermia
... A total of 173 miRNAs were found to be differentially expressed in NOA patients compared to controls, with 19 up-regulated miR- NAs (See additional file 1: Table S1 for Differentially up[r] ...
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CHES-1-like , the ortholog of a non-obstructive azoospermia- associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis
... Ectopic expression of CHES-1-like in germ cells induces testis tumor formation Since CHES-1-like loss of function did not result in spermatogenesis defects, we decided to examine whether[r] ...
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Preferential Y-Y pairing and synapsis and abnormal meiotic recombination in a 47,XYY man with non obstructive azoospermia
... A huge variation in number of MLH1 foci has been re- ported in subjects suffering from male infertility (with variety of phenotypes) when compared with the normal fertile controls. It has been reported previously that ...
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A novel stepwise micro-TESE approach in non obstructive azoospermia
... of azoospermia was defined for 38 patients whereas in the remaining 26 it was undefined: 25 were Klinefelter, 12 had a history of chriptorchidism and 1 with micro deletion of the ...with azoospermia had ...
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Long term effects of micro-surgical testicular sperm extraction on androgen status in patients with non obstructive azoospermia
... Due to the adverse effect of TESE on serum T reported in this study, it is recommended that, whenever possible, an etiological treatment of the azoospermia should be attempted before resorting to TESE. For ...
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The treatment of obstructive azoospermia by intracytoplasmic sperm injection
... : Testicular needle biopsy, open biopsy epididymal aspiration and intracytoplasmic sperm injection in obstructive azoosper- mia:. : Clinical application of intracytopla[r] ...
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The prevalence of Y chromosome microdeletions in Pakistani infertile men
... of azoospermia and oligozoospermia was made on the basis of semen analysis, according to World Health Organization standard as <20×10 6 sperm/ml ...with obstructive azoospermia and abnormal ...
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INTRACYTOPLASMIC SPERM INJECTION (ICSI) OUTCOME IN MEN WITH AZOOSPERMIA
... with azoospermia involves percutaneous testicular sperm aspiration (PTSA) or testicular sperm extraction (TESE) according to the type of azoospermia combined with intracytoplasmic sperm injection ...of ...
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Genes located in Y-chromosomal regions important for male fertility show altered transcript levels in cryptorchidism and respond to curative hormone treatment
... Cryptorchidism is the most frequent congenital pediatric urological disorder in boys and represents the most common cause of non-obstructive azoospermia in man [1 – 3]. During mini-puberty, which peaks ...
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