oesophageal adenocarcinoma
Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label, randomised phase 3 trial
... This study showed that more intensive neoadjuvant chemotherapy with four cycles of ECX provided no overall or disease-free survival advantage over two cycles of CF in 897 patients with oesophageal ...
12
Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma
... on oesophageal adenocarcinoma cell lines that express both AR1 and AR2 (50, 51), which may potentially contribute to delaying recovery from DNA damage following irradiation, enhancing ...
10
Circulating microRNAs as potential biomarkers to detect transformation of Barrett’s oesophagus to oesophageal adenocarcinoma
... Interestingly, tissue miRNA profiles of BO adjacent to high-grade dysplasia were also similar to those of high- grade dysplasia and OAC. Therefore, we could expect Figure 3 (A) Hierarchical clustering analysis based on ...
8
MicroRNA 330 5p as a putative modulator of neoadjuvant chemoradiotherapy sensitivity in oesophageal adenocarcinoma
... Oesophageal adenocarcinoma (OAC) is the sixth most common cause of cancer deaths worldwide, and the 5-year survival rate for patients diagnosed with the disease is approxi- mately ...
15
Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma
... Neoadjuvant chemoradiation therapy (CRT) is increasingly the standard of care for locally advanced oesophageal cancer. A complete pathological response to CRT is associated with a favourable outcome. Radiation ...
12
Vitamin D, calcium and dairy intake, and risk of oesophageal adenocarcinoma and its precursor conditions
... Barrett’s Adenocarcinoma Relationship (FINBAR) study is an all-Ireland population- based case – control study that was established to investigate the aetiology of reflux oesophagitis, Barrett’s oesophagus and ...
10
Authentication and characterisation of a new oesophageal adenocarcinoma cell line : MFD 1
... New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal adenocarcinoma (OAC). The MFD-1 cell line was ...
12
Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
... to oesophageal adenocarcinoma development could serve as predictors for disease progression in Barrett’s ...develop oesophageal adenocarcinoma, specifi c markers for the transition of Barrett’s ...
11
Brain metastases in gastro-oesophageal adenocarcinoma: Insights into the role of the human epidermal growth factor receptor 2 (HER2)
... gastro-oesophageal adenocarcinoma and CNS ...with oesophageal cancer, 9 patients developed BMets—5 of them were HER2 positive based on immunohistochemistry (IHC) (Abu Hejleh et al, ...
6
Effects of Omegaven®, EPA, DHA and oxaliplatin on oesophageal adenocarcinoma cell lines growth, cytokine and cell signal biomarkers expression
... In the current series of experiments, the most pro- found effects on cytokine production were on VEGF. The treatment of OE33 cells with DHA, Omegaven® and oxaliplatin in this experiment, showed significant decreases in ...
9
Putting oesophageal cancer on the RACK A study of the RACK1 scaffolding protein in oesophageal adenocarcinoma
... non-cancerous oesophageal epithelium has been questioned as it has been reported to have dysplastic properties and to lack some typical epithelial cell characteristics (Underwood et ...two oesophageal ...
25
Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium
... As an increased duration of breastfeeding among women is associated with a substantially decreased risk of OAC,[11, 12] oxytocin is another conceivable mediator of the gender differ- ence. Oxytocin levels are much higher ...
13
Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma
... Oesophageal cancer is an aggressive disease with a poor 5 year survival rate of <20% of diagnosed patients. Unfortunately, only 20-30% Oesophageal Adenocarinoma (OAC) patients show a beneficial response ...
14
Proposed follow up programme after curative resection for lower third oesophageal cancer
... Surgery remains the primary curative treatment for oesophageal adenocarcinoma, providing permanent relief of dysphagia and offering the possibility of cure. A recent compilation of the world literature by ...
8
Decomposition of mutational context signatures using quadratic programming methods
... of oesophageal adenocarcinoma was part of the oesophageal International Cancer Genome Consortium (ICGC) ...The oesophageal ICGC project was funded through a programme and infrastructure grant ...
7
Peptide hydrogels — a tissue engineering strategy for the prevention of oesophageal strictures
... evaluate oesophageal cell response and characterization of cell function through morphology, viability, migration, and typical marker expression in order to identify optimal hydrogels for each cell ...in ...
12
Gastro Oesophageal Reflux in Children with Severe Respiratory Symptoms clinical Spectrum and Management
... Gastro oesophageal Reflux in Children with Severe Respiratory Symptoms Clinical Spectrum and Management ORIGINAL ARTICLE Gastro oesophageal Reflux in Children with Severe Respiratory Symptoms Clinical[.] ...
6
Palliative radiotherapy in addition to self expanding metal stent for improving dysphagia and survival in advanced oesophageal cancer (ROCS: Radiotherapy after Oesophageal Cancer Stenting): study protocol for a randomized controlled trial
... Palliative radiotherapy in addition to self-expanding metal stent for improving dysphagia and survival in advanced oesophageal cancer ROCS: Radiotherapy after Oesophageal Cancer Stenting[r] ...
9
Staging of oesophageal cancer
... normal oesophageal wall is less than 3 mm on CT, and individual layers cannot be identified, so T1 and T2 tumours cannot be ...peri- oesophageal fat may be seen as ill-defined soft tissue stranding but T3 ...
6
The commissural ganglia of the lobster, homarus gammarus, (L)
... inferior oesophageal nerves ( see Table ...posterior oesophageal sensors and from mouthpart receptor 1 ; see Chapter 3 Introduction part b ), motor axons ( from putative motorneurons in the suboesophageal ...
241