old rats
The effect of fasting and refeeding on the ultrastructure of the hypothalamic paraventricular nucleus in young and old rats
... tricular (PVN) nuclei that receive afferent neural and hormonal signals, were shown to control food intake, energy homeostasis, and body mass [3, 6]. In a previ- ous work we investigated ultrastructural alterations in ...
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Ultrastructure of the ventromedial hypothalamic nucleus in fasted and refed young and old rats
... of old rats in an experimental model of ...months old, n = 12) and old (24 months old, n = 12) male Wistar rats were fasted for 48 hours, then refed for 24 hours and sampled ...
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Liver mitochondrial dysfunction is reverted by insulin like growth factor II (IGF II) in aging rats
... Results in this paper showed that mitochondrial dys- function leading to apoptosis (by caspase activation) was normalized by IGF-II therapy, at low doses. In fact, IGF- II treatment during 30 days recovered mitochondrial ...
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Sinensetin regulates age related sarcopenia in cultured primary thigh and calf muscle cells
... the old group cells upon SIN treatment compared to that in the the untreated old group ...in old rats ...treated old rats satellite cells group compared to those in the ...
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Induction of Autologous Bone Marrow Stem Cells by Low Level Laser Therapy Has Beneficial Effects on the Kidneys Post Ischemia Reperfusion Injury in the Rat
... of rats that had undergone ischemia-reperfusion injury ...7-month-old rats for 15 or 30 ...2-3-month-old rats. Rats were then divided randomly into two groups of control and ...
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Update on critical evidence for use of carnitine analogs in clinical practice in CNS disorders
... Comparison of the effects of l -carnitine and acetyl- l -carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats.. Nutriti[r] ...
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Effect of age and environmental factors on insulin release from the perfused pancreas of the rat
... 12-mo-old rats, and was only 25-33% of that of 2-mo-old ...mo-old rats fed either sucrose or chow was between three and four times that of 2-mo-old control rats, and these ...
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Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats
... Due to the labor intensity and sample size needed for the single fibre experiments we assessed single muscle fibre size and contractile properties only in the gastrocnemius muscle isolated from XJB-treated/untreated ...
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Effects of early stage aging on locomotor dynamics and hindlimb muscle force production in the rat
... adult rats aged 6–8 months and ‘early aged’ 24-month-old rats ( Rattus norvegicus , Fischer 344 Brown Norway ...aged rats moved significantly more slowly, sustained longer hindlimb support ...
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... month-old rats as reported in this work could imply a decreased tendency to orchestrate the survival strategy during episodes of local ischemia occurring in the left ...
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Vol 72, No 2 (2020)
... Previous studies have shown that infusion of ghrelin positively influences the total number of thymocytes and size of the thymus in 14-, 20- and 24-month-old rats, and that thymic adiposity is reduced ...
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Hepatoprotection and neuroprotection induced by low doses of IGF II in aging rats
... untreated old rats; O+IGF-II: aging rats treated with IGF-II; PCC: protein carbonyl content; RH123: rhodamine 123 dye; S: sensitivity; SOD: superoxide dismutase; TAS: total antioxidant status; Yco: ...
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Original Article Effects of hydrogen peroxide on phenylephrine-induced contraction of abdominal or thoracic aorta from adult rats
... Finally, age is considered as a factor that signifi- cantly decreases aortic blood compliance. In vivo studies have reported that the values of the differential pressure (DP) and mean arterial pressure (MAP) were ...
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“Cisplatin Modulates poly(adp-ribos)yl Polymerase 1 Inhibition and DNA Internucleosomal Fragmentation in Rat Liver Nuclei” by Irina Artsruni, Anush Asatryan, Karine Matinyan, Emil Gevorgyan, Armenia.
... week old rats coincided with greater suppression of DNA ...week old rats could be consequential to at least two biochemical events: poly(ADP-ribos)ylation of chromatin associated proteins by ...
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Response of tibialis anterior tendon to a chronic exposure of stretch-shortening cycles: age effects
... young rats (12 weeks age) while inducing substantial per- formance deficits and a lack of muscle hypertrophy in old rats (30 months age) after ...aging rats did not tolerate exposure to ...
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Age-related changes in the mRNA levels of CYP1A1, CYP2B1/2 and CYP3A1 isoforms in rat small intestine
... carcinogenesis within intestinal epithelium. Probably, the CYP1A1 isoform plays a particular role in this process. There are suggestions that biotransformation of PAHs and also food-derived xenobiotics into active ...
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Original Article Are there differences between Sprague-Dawley and Wistar rats in long-term effects of ovariectomy as a model for postmenopausal osteoporosis?
... animals, rats are able to reach a new balance in the bone formation and remodeling cycle in a shorter period of ...animals, rats are most widely used to establish models of ...female rats are similar ...
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Age-Related Changes in Doxorubicin-Induced Oxidative Damage: Protective and Pretreatment Effects of Short-Term Aerobic Exercise
... Currently, the principal mechanism of DOX- induced cardiotoxicity is believed to be increased oxidant production by the mitochondria (22, 23), which is a main site of ROS production. Exercise seems to increase the oxygen ...
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Influence of Prenatal and Postnatal Stress on the Sexual Behavior of Rats
... pregnant rats did not affect the behavior of their ...with rats, does not influence sexual behavior in boys and has but a small influence in the sexual behavior of ...
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Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory
... Figure 2. Biochemical analyses of CS-GAG sulfation. 12-, 18-month old brains shows an increase in the ratio C4S/C6S in the PNNs fraction. (A) Measurement of the total CS GAGs quantity in the various fractions ...
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