open-reading frame
The Herpesvirus Saimiri Open Reading Frame 73 Gene Product Interacts with the Cellular Protein p32
... The role of the gamma-2 herpesvirus open reading frame (ORF) 73 gene product has become the focus of considerable interest. It has recently been shown that the Kaposi’s sarcoma-associated herpesvirus ...
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In Vitro and In Vivo Characterization of a Murine Cytomegalovirus with a Mutation at Open Reading Frame m166
... within open reading frame m166 and is designated as Rvm166 ...382-amino-acid open reading frame) in reference to the ge- nome sequence of the wild-type Smith strain (32) ...
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Murine Gammaherpesvirus 68 Open Reading Frame 11 Encodes a Nonessential Virion Component
... The human gammaherpesviruses, EBV and the Kaposi’s sarcoma-associated herpesvirus (KSHV), do not readily enter the lytic cycle in vitro and exhibit very narrow species tropisms in vivo. These limitations upon analysis ...
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Reverse genetic characterization of the natural genomic deletion in SARS Coronavirus strain Frankfurt 1 open reading frame 7b reveals an attenuating function of the 7b protein in vitro and in vivo
... BioMed CentralVirology Journal ss Open AcceResearch Reverse genetic characterization of the natural genomic deletion in SARS Coronavirus strain Frankfurt 1 open reading frame 7b reveals an attenuating[.] ...
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Targeted Genome Sequencing Reveals Varicella-Zoster Virus Open Reading Frame 12 Deletion
... ABSTRACT The neurotropic herpesvirus varicella-zoster virus (VZV) establishes a lifelong latent infection in humans following primary infection. The low abundance of VZV nucleic acids in human neurons has hindered an ...
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Open Reading Frame 33 of a Gammaherpesvirus Encodes a Tegument Protein Essential for Virion Morphogenesis and Egress
... Tegument is a unique structure of herpesvirus, which surrounds the capsid and interacts with the envelope. Morphogenesis of gammaherpesvirus is poorly understood due to lack of efficient lytic replication for Epstein- ...
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Open Reading Frame III of Borna Disease Virus Encodes a Nonglycosylated Matrix Protein
... The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications ...
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Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.
... Although the amino acid sequence indicates that the UL97 product may have protein kinase or phosphotransferase activity, Sullivan and coworkers 31 identified this open reading frame as t[r] ...
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Human Herpesvirus 6 Open Reading Frame U83 Encodes a Functional Chemokine
... Some viruses including herpesviruses have undergone evolution to benefit viral infection and propagation by pirating and modifying host genes such as chemokine genes. Human herpesvirus 6 (HHV-6), acutely or persistently ...
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Structure of the Open Reading Frame 49 Protein Encoded by Kaposi's Sarcoma-Associated Herpesvirus
... ABSTRACT Herpesviruses alternate between the latent and the lytic life cycle. Switching into the lytic life cycle is important for herpesviral replication and disease pathogenesis. Activation of a transcription factor ...
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Norwalk Virus Open Reading Frame 3 Encodes a Minor Structural Protein
... Norwalk virus (NV) is a causative agent of acute epidemic nonbacterial gastroenteritis in humans. The inability to cultivate NV has required the use of molecular techniques to examine the genome organization and ...
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Dissection of a Novel Nuclear Localization Signal in Open Reading Frame 29 of Varicella-Zoster Virus
... Open reading frame 29 (ORF29) of varicella-zoster virus (VZV) encodes a 120-kDa single-stranded DNA binding protein (ORF29p) that is not packaged in the virion and is expressed during ...
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Initiation at the Third In-Frame AUG Codon of Open Reading Frame 3 of the Hepatitis E Virus Is Essential for Viral Infectivity In Vivo
... (HEV) open reading frame 3 (ORF3), we constructed five HEV mutants with desired mutations in the ORF1 and ORF2 junction region and tested their levels of in vivo infectivity in ...
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Identification of the E5 open reading frame of human papillomavirus type 16.
... 1071 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Sequencing of the E5 open reading frame ORF of human papillomavirus type 16 revealed an additional nucleotide, a th[r] ...
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Antigenic Domains of the Open Reading Frame 2 Encoded Protein of Hepatitis E Virus
... The antigenic composition of the hepatitis E virus (HEV) protein encoded by open reading frame 2 (ORF2) was determined by using synthetic peptides. Three sets of overlapping 18-, 25-, and 30-mer ...
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Human Cytomegalovirus UL131 Open Reading Frame Is Required for Epithelial Cell Tropism
... Epithelial cells are one of the prominent cell types infected by human cytomegalovirus (HCMV) within its host. However, many cultured epithelial cells, such as ARPE-19 retinal pigmented epithelial cells, are poorly ...
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The Hepatitis E Virus Open Reading Frame 3 Product Interacts with Microtubules and Interferes with Their Dynamics
... Hepatitis E virus (HEV) is the causative agent of hepatitis E, a major form of viral hepatitis in developing countries. The open reading frame 3 (ORF3) of HEV encodes a phosphoprotein with a ...
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Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein.
... The vpr recombinant protein was partially purified by In addition to three structural genes, gag, pol, and env, which are commonly found in replication-competent animal retroviruses, hum[r] ...
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Bovine herpesvirus 1 U(s) open reading frame 4 encodes a glycoproteoglycan.
... To determine whether the 65-kDa protein released from the US ORF4 proteoglycan carries carbohydrates, [35S]methionine-cysteine-labeled proteins from the supernatants of cells infected wi[r] ...
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E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene.
... In C127 cells, pHLB1 normally induced only about one-half as many foci as the full-length BPV clone, Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest MATERIALS AND METHO[r] ...
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