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orbitofrontal cortex

Non reward neural mechanisms in the orbitofrontal cortex

Non reward neural mechanisms in the orbitofrontal cortex

... primate orbitofrontal cortex fire fast, and as soon as the reward stops moving (within sight) towards the macaque, or is slowly removed (by being moved backwards), the non-reward neurons start to fire, and ...

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Medial reward and lateral non reward orbitofrontal cortex circuits change in opposite directions in depression

Medial reward and lateral non reward orbitofrontal cortex circuits change in opposite directions in depression

... mid orbitofrontal cortex BA13 has direct reciprocal connections with the perirhinal cortex BA 36 (Kondo et ...entorhinal cortex BA 28 to the hippocampus (Kesner and Rolls, ...medial ...

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Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli

Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli

... and orbitofrontal cortex respond to the sight, taste, and smell of food, as well as to stimuli associated with food reward (Sanghera et ...and orbitofrontal cortex to food during fasting are ...

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The roles of the orbitofrontal cortex via the habenula in non reward and depression, and in the responses of serotonin and dopamine neurons

The roles of the orbitofrontal cortex via the habenula in non reward and depression, and in the responses of serotonin and dopamine neurons

... the orbitofrontal cortex that sends projections to the ventral striatum (Williams et ...the orbitofrontal cortex and its closely connected areas such as the anterior cingulate cortex ...

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Disappearance of treatment-resistant depression after damage to the orbitofrontal cortex and subgenual cingulate area: a case study

Disappearance of treatment-resistant depression after damage to the orbitofrontal cortex and subgenual cingulate area: a case study

... Mood change after brain damage has been reported previously. Gainotti [12] found that patients with left- sided lesions were more likely to demonstrate emotional tendencies for “catastrophic reactions” (anxiety, tears, ...

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Involvement of the lateral orbitofrontal cortex in context-induced and cocaine-primed reinstatement of cocaine seeking behavior in rats

Involvement of the lateral orbitofrontal cortex in context-induced and cocaine-primed reinstatement of cocaine seeking behavior in rats

... orbitofrontal cortex and anterior cingulate, diminished baseline blood glucose metabolism in the frontal cortex, and enhanced cue-evoked activation of the orbitofrontal cortex, some of ...

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Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

... In accordance with our first hypothesis, MDD patients showed a significant reduction in OFC thickness com- pared to HCs. Our results are similar to previous studies reporting a decrease in OFC thickness in MDD patients ...

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The orbitofrontal cortex and emotion in health and disease, including depression

The orbitofrontal cortex and emotion in health and disease, including depression

... lateral orbitofrontal cortex region is primarily on the right of the brain, and extends round the inferior frontal convexity to the ventral parts of the inferior frontal gyrus pars triangularis (BA45), ...

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Increased functional connectivity of the posterior cingulate cortex with the lateral orbitofrontal cortex in depression

Increased functional connectivity of the posterior cingulate cortex with the lateral orbitofrontal cortex in depression

... frontal cortex to the hippocampal system via the posterior cingulate cortex, as well as by the perirhinal and entorh- inal cortex pathway are the two main routes 22,38,40,41 ...lateral ...

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Relative valuation of pain in human orbitofrontal cortex

Relative valuation of pain in human orbitofrontal cortex

... The valuation of health-related states, including pain, is a critical issue in clinical practice, health economics, and pain neuroscience. Surprisingly the monetary value people associate with pain is highly ...

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Autism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits

Autism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits

... cerebral cortex were prepared as previously described in Schmeisser et ...a cortex was quickly dissec- ted out and homogenized in HEPES-buffered sucrose (320 mM sucrose, 5 mM 4-(2-hydroxyethyl)-1-piperazi- ...

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Lexical olfaction recruits olfactory orbitofrontal cortex in metaphorical and literal contexts

Lexical olfaction recruits olfactory orbitofrontal cortex in metaphorical and literal contexts

... The present study extends previous work on the grounding of abstract concepts through metaphorical mappings to a novel domain, namely olfaction, showing that the comprehension of conventional figurative expressions ...

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Updating existing emotional memories involves the frontopolar/orbitofrontal cortex in ways that acquiring new emotional memories does not

Updating existing emotional memories involves the frontopolar/orbitofrontal cortex in ways that acquiring new emotional memories does not

... frontopolar/ orbitofrontal (OFC) activity when people learned picture-location associations for old negative pictures than for new negative pictures, but frontopolar OFC activity did not significantly differ ...

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Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

... poral cortex, display decreased total GR mRNA expres- sion in both schizophrenia and bipolar disorder ...entorhinal cortex in bipolar disorder but not schizo- phrenia, and is decreased in the DLPFC in ...

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Obesity induced structural and neuronal plasticity in the lateral orbitofrontal cortex

Obesity induced structural and neuronal plasticity in the lateral orbitofrontal cortex

... Taken together, neither presynaptic glutamate release nor the number or function of postsynaptic AMPARs on pyramidal neurons were changed in rats with extended or restricted access to a [r] ...

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A preliminary study of orbitofrontal activation and hypersociability in Williams Syndrome

A preliminary study of orbitofrontal activation and hypersociability in Williams Syndrome

... and typically developing individuals (TD). a Region-of-interest (ROI) analyses in standard space of the right (Rt) medial and lateral orbitofrontal cortex (OFC). Left OFC and bilateral amygdala showed no ...

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Dysfunction of orbitofrontal and dorsolateral prefrontal cortices in children and adolescents with high-functioning pervasive developmental disorders

Dysfunction of orbitofrontal and dorsolateral prefrontal cortices in children and adolescents with high-functioning pervasive developmental disorders

... the orbitofrontal cortex (OFC) has been implicated in the neuropsychological pathophysiology of PDD, in the context that PDD pa- tients exhibit impaired social behavior, social inter- action, and ...the ...

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Orbitofrontal Dysfunction Related to Both Apathy and Disinhibition in Frontotemporal Dementia

Orbitofrontal Dysfunction Related to Both Apathy and Disinhibition in Frontotemporal Dementia

... Finally, correlation analysis between the apathy sub- test of the NPI and brain activity did not reveal signifi cant results. This is probably due to inadequate variance in the apathy scores in our population as a whole. ...

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Insula and Orbitofrontal Cortical Morphology in Substance Dependence Is Modulated by Sex

Insula and Orbitofrontal Cortical Morphology in Substance Dependence Is Modulated by Sex

... MATERIALS AND METHODS: Twenty-eight abstinent SDI (17 men/11 women) were compared with 28 controls (13 men/15 women). Cortical thicknesses and volumes were computed by using FreeSurfer. After controlling for age and ...

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Altered orbitofrontal sulcogyral pattern in schizophrenia

Altered orbitofrontal sulcogyral pattern in schizophrenia

... in orbitofrontal cortex in schizophrenia ...prefrontal cortex, possibly related to a neurodevelopmental variation in the prefrontal paralimbic ...

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