organic anion transporting polypeptide (SLCO)
Study on the Expression of Organic Anion Transporting Polypeptide (oatp2a1) in Rat with Spleen Deficiency Syndrome and the Exploration of Clinical Significance
... of organic anion transporting polypeptide (oatp) superfamily member 2a1 (oatp2a1) mRNA in rat with spleen deficiency syndrome and the significance in transportation and transformation of ...
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Effects of Organic Anion Transporting Polypeptide (OATP1B1/SLCO1B1) Genetic Polymorphism on Statin Therapy
... of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion transporting polypeptide 1B1 (OATP1B1) multidrug resistance 1 and OATP1B1 ...
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The Effect of Cangfudaotan Tang on Expression of Organic Anion Transporting Polypeptide (oatp4a1) in Rat Ovary and Uterus Tissues of Obese PCOS
... that Organic Anion Transporting Polypeptide might be the material basis involved in transportation and transformation of ...ganic Anion Transporting Polypeptide is ...
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Localization of organic anion transporting polypeptide (Oatp) 1a4 and Oatp1c1 at the rat blood-retinal barrier
... Background: Organic anion transporting polypeptide (Oatp) transporters at the blood – brain barrier (BBB) and the blood-retinal barrier (BRB), which consists of retinal capillary endothelial ...
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Organic anion transporting polypeptide 1a/1b–knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs
... Organic anion transporting polypeptides (human: OATP, gene SLCO; rodents: Oatp, gene Slco) belong to the superfamily of the solute carrier class of organic anion ...
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P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions
... whereas organic anion transporters, organic anion-transporting polypeptides (OATPs), and organic cation transporters are members of the solute-carrier ...
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Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers
... Despite high Ct-OATP1B3 mRNA expression levels in colon cancer cells, its protein expression was not detected in the soluble membrane fraction of such cells when using either anti-OATP1B[r] ...
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Effects of Cangfudaotan Tang on Expression of Organic Anion Transporting Polypeptide (oatp2b1) in Liver and Kidney Tissues of Rats with Phlegm Dampness Type Polycystic Ovary Syndrome (PCOS)
... indicates, organic anion transporter polypeptide (oatp) can efficiently transport a variety of foreign organisms, which plays an important role in transporta- tion and transformation of phlegm ...
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Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats
... The translational challenges associated with targeting P-gp indicate a need for a change in thought regarding BBB transporters. Our laboratory has proposed that a more rational strategy would be to target SLC trans- ...
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Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome
... Within individual tumor grades, OATP1B3 expression was associated with improved 5-year survival, but not recurrence in patients with poorly differentiated tumors.. Conclusion: OATP1B3 [r] ...
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Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets
... Figure 1 ribbon representation of the three-dimensional model of organic anion-transporting polypeptide 1B3. TM domains, a probable substrate binding site and the conserved amino acid side ...
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Molecular and biological characterization of the Amblyomma americanum organic anion transporter polypeptide
... The organic anion transporting polypeptides [abbreviated as ‘Oatp’ in non-human organisms and ‘OATP’ in humans (Meier- Abt et ...[non-human, Slco ; human, SLCO (Meier-Abt et ...
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Does ethnic variability exist in the systemic exposures of oatp1a2 substrates?fexofenadine in taiwanese?
... in organic anion transporting polypeptide 1A2 activity among the Taiwanese population via an analysis of 3 pharmacokinetic studies completed in a total of 103 healthy male Taiwanese ...of ...
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Primary and secondary thyroid hormone transporters
... activity in comparison to the wild type mice [10-12]. On the basis of these data it was assumed that addi- tional TH transporters ( “ secondary TH transporters ” ) or differences in their expression patterns and ...
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Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide
... OAT3, OATP1B1, and OATP1B3 transporters mediated renal and hepatic uptake of catalposide, which would be excreted via renal and biliary routes with or without coupling non-CYP mediated metabolism. Therefore, we first ...
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In situ prepared composite materials of PEDOT: PSS buffer layer metal nanoparticles and their application to organic solar cells
... using organic capping agents such as poly(ethylene glycol) (PEG) or poly(vinyl pyrrolidone) (PVP) and the mixing/dispersion of synthesized metal NPs with a photo- active or PEDOT:PSS ...
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Crystallographic and physicochemical studies on metal and anion substituted human lactoferrin : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemistry at Massey University
... the anion and Tyr92 (the His253 and Asp60 residues have to adjust to the new copper ...the anion is now able to adjust by a small rotation and take up a monodentate coordination mode, ...
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STOOL LOSSES AND ACIDOSIS IN DIARRHEAL DISEASE OF INFANCY
... calculated stool water organic anion concentration;. the specimens svere collected simultaneously[r] ...
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EFFECT OF PINEAPPLE (ANANAS COMOSUS) AND UZIZA (PIPER GUINEENSE) EXTRACTS ON FEXOFENADINE BIOAVAILABILITY: POSSIBLE ROLE OF P-GLYCOPROTEIN (P-GP) AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs)
... of organic anion transporting polypeptides (OATPs) during the intestinal absorption suggesting that the combined use of pineapple or uziza- containing diet with fexofenadine may require close ...
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Identification potential biomarkers in pulmonary tuberculosis and latent infection based on bioinformatics analysis
... Na+/K+ transporting, alpha 4 polypeptide; BATF : Basic leucine zipper transcription factor, ATF-like; BH: Benjamin and Hochberg; BP: Biological process; CLCN7 : Chloride channel, voltage-sensitive 7; CREBBP ...
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