osteoblast differentiation
Tridax procumbens flavonoids promote osteoblast differentiation and bone formation
... significant upregulation of osterix, Bmp-2, Bmp-4 and Bmp-7 compared to control group (Figs. 1h, 2). Osteo- blasts play a crucial role in the bone formation, differenti- ating from mesenchymal stem cells is regulated by ...
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Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation
... of osteoblast growth by MTA1 under the hypoxic microenvironment after bone fracture is a necessary response heading to fracture ...proliferating osteoblast population to support the healing ...
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Osteoblast derived VEGF regulates osteoblast differentiation and bone formation during bone repair
... studied. Osteoblast lineage cells, along with chondrocytes, are considered impor- tant sources of VEGF in the bone environment (20, ...by osteoblast precursors in the perichondrium of cartilage models of ...
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TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation
... Transforming growth factor-beta (TGF-β)/bone morphogenic protein (BMP) signaling is in- volved in a vast majority of cellular processes and is fundamentally important throughout life. TGF-β/BMPs have widely recognized ...
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MicroRNAs: Synthesis, Gene Regulation and Osteoblast Differentiation
... in differentiation of MSCs to osteoblasts Mesenchymal stem cells (MSCs), isolated from bone marrow, cord blood, peripheral blood, fallopian tube, fetal liver and lung, have the ability to self-renewal and ...
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Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways
... and differentiation, cross-talking with other signaling pathways such mitogen activated kinase (MAPKs) are involved in bone ...late osteoblast differentiation through MAPK signaling ...
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Targeting miRNAs in Osteoblast Differentiation under Malnutrition Conditions
... pathway Osteoblast differentiation Leukocyte transendothelial VEGF signaling pathway NF-kappa B signaling pathway Apoptosis B cell receptor signaling ...
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Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation
... Osteoblast differentiation from mesenchymal cells is regulated by multiple signalling path- ...for osteoblast differen- tiation in ...of differentiation to initiate expression of the ...
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Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation
... in osteoblast differentiation and function is complex and the effects of XO inhibition on other cell types in vivo may exert additional actions that are not evident in ...
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Epigenetic regulation of Runx2 transcription and osteoblast differentiation by nicotinamide phosphoribosyltransferase
... the hind limbs. External soft tissue was discarded, and the bones were place in a-MEM supplemented with 1% penicillin/streptomycin. Both ends of the femur and tibia were clipped. An 18-gauge needle was inserted into the ...
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Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development
... formation. Osteoblast precursors, endothelial cells and osteoclasts migrate from perichondrium into primary ossification centers of cartilage templates of future bones in response to Vegfa secreted by ( ...
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5′-hydroxy Auraptene stimulates osteoblast differentiation of bone marrow-derived mesenchymal stem cells via a BMP-dependent mechanism
... stimulates osteoblast differentiation of mBMSCs We examined the effect of 5′-HA on the differentiation of mBMSCs into osteoblastic cell ...the differentiation of mBMSCs into osteoblasts in a ...
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Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh
... Two osteoblast differentiation factors, Runx2 and Atf4, have been shown to activate Ihh expression and regulate chondrocyte proliferation and differentiation by binding directly to the Ihh proximal ...
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Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation
... suppresses osteoblast differentiation and sustains bone marrow mesenchymal progenitors during postnatal ...and osteoblast differentiation in primary cultures of bone marrow mesenchymal ...
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Original Article JAK2/STAT5 signaling in the lipopolysaccharide (LPS)-induced inhibition of osteoblast differentiation
... the osteoblast differentiation via measuring the Alkaline phosphatase (ALP) activity, matrix mineralization, and the expression of ALP, Procollagen type I N-terminal propeptide (PINP), Runt-related ...
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Maf promotes osteoblast differentiation in mice by mediating the age related switch in mesenchymal cell differentiation
... undergo differentiation into various anchorage-dependent cell types, including osteoblasts and ...favor differentiation into adipocytes, resulting in an increased number of adipocytes and a decreased number ...
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Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice
... controls at E15.5 and P1 (Figure 4A). In contrast, expression of osteocalcin mRNA, a marker of terminally differentiated osteoblasts initially detectable in WT mice at P1, was nearly absent in mutant bones by P9 (Figure ...
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Osteoblast differentiation of rabbit adipose-derived stem cells by polyethylenimine-mediated BMP-2 gene transfection in vitro.
... Bone morphogenetic proteins (BMPs) belong to the transforming growth factor b superfamily. Studies have shown that BMPs could induce osteogenesis in non-bone tissues, thus playing important roles in bone development and ...
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The effect of depression on fracture healing and osteoblast differentiation in rats
... cells were cultured in an osteogenic differentiation medium to compare their osteogenic potential. After 21 days of osteo- genic induction, the ALP staining intensity was obviously lower in depressive BMSCs, and ...
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Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
... during osteoblast differentiation (Figure 6A; Additional file ...during osteoblast differenti- ation was increased at day 9 and remained steady to day 28 (Figure ...
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