outer membrane
Outer Membrane Vesicle Production Facilitates LPS Remodeling and Outer Membrane Maintenance in Salmonella during Environmental Transitions
... ABSTRACT The ability of Gram-negative bacteria to carefully modulate outer membrane (OM) composition is essential to their survival. However, the asymmetric and heterogeneous structure of the Gram-negative ...
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Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram Negative Bacteria
... The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer composed of lipopolysaccharides (LPS) in the outer leaflet and glycerophospholipids (PL) in the inner leaflet ...inner ...
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Genetic Similarity of Gonococcal Homologs to Meningococcal Outer Membrane Proteins of Serogroup B Vaccine
... IMPORTANCE Gonorrhea, a sexually transmitted disease, causes substantial global morbidity and economic burden. New prevention and control measures for this dis- ease are urgently needed, as strains resistant to almost ...
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Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
... bacterial outer membrane vesicles (OMVs) comprised of LPS and other cell wall components to culture medium is sufficient to activate caspase-11 in macrophages, which are able to extract and import LPS from ...
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Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates
... S4 outer membrane, the Schu S4 type IV pilus fiber building block protein (Q5NGF5; gene, ...and outer membrane samples, but the BLAST searches showed that there was no match in the LVS ...
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Understanding antibiotic resistance via outer membrane permeability
... bacterial outer cell wall has been identified as a challenging barrier that prevents a sufficient antibiotic effect to be attained at low doses of the ...an outer membrane that delimits the periplasm ...
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LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella
... ABSTRACT Outer membrane vesicles (OMV) are proposed to mediate multiple functions during pathogenesis and ...the outer membrane (OM) and subsequent OMV ...
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Structural basis for outer membrane lipopolysaccharide insertion
... applying membrane stretch was applied, by simulating under different lateral pressures, from -10 to -100 ...with membrane lysis usually following within 10 ...other outer membrane proteins: ...
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Bacterial outer membrane vesicles and vaccine applications
... Proteoliposomes, outer membrane vesicles (OMV), proteosomes (1) and very small size proteoliposomes (2) are examples of the different approaches of vesicle formulations obtained from ...
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Membrane Distribution of the Pseudomonas Quinolone Signal Modulates Outer Membrane Vesicle Production in Pseudomonas aeruginosa
... stimulating outer membrane vesicle (OMV) ...the outer membrane, causing expansion of the outer leaflet and consequently inducing ...the outer membrane before it can ...
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A Stress Response Monitoring Lipoprotein Trafficking to the Outer Membrane
... The outer membrane built by Gram-negative bacteria such as Escherichia coli forms a barrier that prevents antibiotics from entering the cell, limiting clinical op- tions at a time of prevalent antibiotic ...
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Structural and functional studies of bacterial outer membrane proteins
... Experiments of gentamicin interaction with OmpC20 and OmpC33 show that this antibiotic triggers closures of OmpC channels. Although gentamicin does not depend on the OmpC pathway to go through the outer ...
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Comparison of outer membrane protein and biochemical profiles of Haemophilus aegyptius and Haemophilus influenzae biotype III
... influenzae biotype III had major outer membrane proteins between 27 and 41.5 kDa representing two additional protein profiles.... OUTER MEMBRANE PROTEINS OF HAEMOPHILUS SPP..[r] ...
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Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence
... flexneri’s outer membrane is not required for intracellular ...or outer membrane, we also performed time-lapse microscopy on the pbgA mutant, which has cardiolipin in the inner membrane, ...
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Antibody Responses to Recombinant Protein Fragments of the Major Outer Membrane Protein and Polymorphic Outer Membrane Protein POMP90 in Chlamydophila abortus-Infected Pregnant Sheep
... major outer membrane protein (MOMP)-specific monoclonal antibody (31), and recombinant protein fragments of the MOMP (vari- able segment 2 [VS2] MOMP indirect enzyme-linked immu- nosorbent assay [iELISA]) ...
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Detection of Chlamydia pneumoniae Specific Antibodies Binding to the VD2 and VD3 Regions of the Major Outer Membrane Protein
... tis. Notably, all sera that tested positive only for C. pneumoniae reacted with OMP2 from both C. pneumoniae and C. tracho- matis (Fig. 4B). Likewise, C. trachomatis immune sera dis- played OMP2 reactivity at ...
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Hematoma within the Outer Membrane of the Arachnoid Cyst Located in the Middle Fossa: A Mechanism of Development of Chronic Subdural Hematoma Associated with Arachnoid Cysts
... the outer mem- brane of the AC and CSDH, and endoscopic cystocisternostomy were performed to relieve her ...the outer membrane of the CSDH demonstrated an arachnoid cell layer and hemorrhage from the ...
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Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles
... Fourth, proteins directed to the OMV are predominantly acidic. Previous reports showed that OMV and OM vary in terms of lipid and protein compositions. As evidence for lipid variation, differ- ent LPS were detected in ...
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Sequential Translocation of Polypeptides across the Bacterial Outer Membrane through the Trimeric Autotransporter Pathway
... ABSTRACT Trimeric autotransporter adhesins (TAAs) are a family of bacterial outer membrane (OM) proteins that are comprised of three identical subunits. Each sub- unit contains an N-terminal extracellular ...
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Immunobiology of Treponema hyodysenteriae outer membrane components
... 78 infected gnotobiotic pigs with Treponema hvodvsenteriae and reported spirochetes within colonic goblet cells by day 2 post infection... spirochetes had invaded enterocytes apparently [r] ...
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