Oxidant Stress
HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction
... the oxidant stress caused by chronic HIV infection could be exacerbated by other fac- tors such as alcohol abuse, which is a common co-morbid condition in this population ...causes oxidant ...
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Na/K-ATPase amplification of oxidant stress; a universal but unrecognized clinical target?
... of oxidant injury appears to be central to the pathogenesis of many clinical problems, some of which have been effectively recalcitrant to current ...of oxidant stress may allow for novel therapies ...
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TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1
... oxidative stress measured by 4-HNE adducts (Figure 8C) was reduced in the kidneys of WT mice treated with the RAC1 inhibitor to the levels seen in Trpm2-KO ...oxidative stress, were higher in WT kidneys ...
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Systemic isradipine treatment diminishes calcium dependent mitochondrial oxidant stress
... mitochondrial oxidant stress in SNc DA neurons, selective negative allosteric modulators could prove more effective neuroprotective agents than isradipine and have a narrower side-effect profile ...
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Regulation of catalase in Neisseria gonorrhoeae Effects of oxidant stress and exposure to human neutrophils
... of oxidant stress on the catalase activity and hydrogen peroxide sensitivity of Neisseria ...of stress; only a single isoenzyme of catalase could be ...
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Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production
... and oxidant stress with ApoB100 degradation via PERPP, and may be relevant to the hypolipidemic actions of dietary PUFAs, the basal regulation of ApoB100 secretion, and hyperlipidemias arising from ApoB100 ...
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Antioxidant and lipid peroxidation protective properties of aqueous plant extracts in mononuclear blood cells under high oxidant stress
... noxious oxidant conditions depends mainly on the enzymatic detoxification processes such as superoxide dismutase, glutathione peroxidase and ...which oxidant or free radical damage play a pathological ...
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Oxidant stress as a regulator of renal function in disease
... Another line of enquiry was the possibility that renal functional improvement was in fact unrelated to anti-oxidant potential but perhaps to a property unique to chemicals with a NAC-like structure, and not shared ...
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Enhanced Sensitivity of the Postnatal Lung to Environmental Insults and Oxidant Stress
... adult alveolar macrophage released similar amounts of neutrophil chemotactic activity and tumor necro- sis factor in response to incubation with lipopolysac- charide (LPS) in vitro. Support for the hypothesis of ...
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Increased Oxidant Stress and Inflammation in Patients with Chronic Schizophrenia
... oxidative stress and inflammation in patients with ...oxidative stress markers has been reported in schizoprenia studies, but with inconsistent ...oxidative stress and inflammation together, nor the ...
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Alcohol induced generation of lipid peroxidation products in humans
... circulating TBARS in patients with alcoholic cirrhosis. The mechanisms that underlie the increase in oxidant stress in ALD are unclear. Although alcoholics often consume a diet deficient in antioxidant ...
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Original Article Tempol protect against hypoxia induced oxidative stress in PC12 cells
... of studies have demonstrated that HIF-1α accu- mulated following by hypoxia, but the beneficial and detrimental effects of HIF-1α elevation is still elusive. Lopez-Hernandez et al revealed that unregulated HIF-1α ...
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Severe Hemolytic Anemia in Black Children with Glucose-6-Phosphate Dehydrogenase Deficiency
... The clinical spectrum of hemolytic anemia as a consequence of oxidant stress in black children.. deficient in erythrocyte glucose-fl-phosphate dehydroge-.[r] ...
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Evaluation of antioxidant and anti-inflammatory effects of red raspberries on chronic nicotine-induced damage: an experimental study
... of respiratory bronchiolitis, interstitial lung disease, idiopathic pulmonary fibrosis. Several studies demonstrated that smoking promotes lung tissue remodelling through oxidant stress, inflammation. ...
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The efficacy of alpha-lipoic acid and/or gabapentin on the oxidant-antioxidant system in patients with diabetic polyneuropathy
... Total antioxidant status (TAS), total oxidant status (TOS), paraoxonase-1 (PON1), the oxidative stress index (OSI) are parameters used for representing oxidative stress. TAS induced by hydroxyl ...
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MEDICINAL ALTERNATIVE FOR CHIKUNGUNYA CURE: A HERBAL APPROACH
... chronic stress, nootropic effect, anti-parkinsonian properties, anti-venom, immunomodulation, anti-inflammatory activity, hematopoiesis, anti-tumor activity, hypolipidemic effects, anti-bacterial property, ...
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Multi-Generational Culture of C. Elegans on a Long-Term Space Flight Revealed Changes in Expression of Genes Involved in Longevity, DNA Repair, and Locomotion
... with the profiles reported by previous studies (19, 45). From the GO classification, it was noted that him-6 and rad-51 were highly expressed in the top 25 genes list, which also included genes involved in other major ...
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Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress
... Soluble factors in the microenvironment are known to regulate microglia polarization [28]. We found ROS and intracellular GSH to be critical for regulating cellular morphologies and a strong association exists between ...
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Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome
... oxidative stress can cause deterioration in the hypotha- lamic-pituitary-adrenal axis and thus FMS can occur ...Oxidative stress can lead to mitochondrial damage and the deterioration of the energy balance ...
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Oxidant/Antioxidant Status, PON1 and ARES Activities, Trace Element Levels, and Histological Alterations in Sheep with Cystic Echinococcosis
... total oxidant/antioxidant capacity in cows with lung cystic echinococcosis, there was a significant increase in arginase activity, TOC and OSI and a significant decrease in TAC in the infected group compared to ...
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