oxidized LDL (ox-LDL)
Bilirubin is independently associated with oxidized LDL levels in young obese patients
... between Ox- LDL and both LDLc and TG (with their inclusion in the regression model of Ox-LDL) are in accordance with lit- ...erature. Ox-LDL level is likely to increase with the ...
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Disease Activity, Oxidized-LDL Fraction and Anti-Oxidized LDL Antibodies Influence Cardiovascular Risk in Rheumatoid Arthritis
... HDL-C, LDL-C and TG concentrations in both groups were measured in a certified commercial ...Anti ox-LDL ELISA Kit, Im- mundiagnostik AG, Bensheim, ...The oxidized LDL fraction in ...
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Vascular incorporation of alpha tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation
... on oxidized LDL (ox-LDL)–medi- ated endothelial dysfunction in male New Zealand White ...to ox-LDL (0– 500 m g/ml) for 4 h produced dose-dependent inhibition of ...
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Oxidized LDL activates fas mediated endothelial cell apoptosis
... Oxidized low density lipoproteins (OxLDL) promote chronic inflammatory responses in the vasculature that give rise to atherosclerotic plaques. Fas ligand (FasL) is naturally ex- pressed on the vascular endothelium ...
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Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio
... against LDL oxidation by artery wall cells ...When LDL receptor knockout mice were fed an atherogenic diet, their apoJ/PON ratios increased by approximately ...mildly oxidized LDL produced by ...
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Gluten free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study
... interest. Oxidized or other types of modified LDL generally are believed to be of importance in atherosclerosis and CVD since such LDL is taken up in the artery wall by macrophages and has immune ...
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Oxidized LDL is Correlated with Urine Albumin in Type 2 Diabetes Mellitus: A Case-Control Study
... of Ox- LDL in the plasma were unavailable ...increase LDL oxidation in diabetic patients in previous studies ...of LDL to oxidation in diabetic ...dense LDL, which is more prone to ...
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... normal LDL-C levels which cannot explain the risk of atherosclerosis in these ...of LDL has higher tendency to get oxidized LDL which enhance pro-inflammatory genes resulting in recruitment of ...
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Effect of immunization against ox-LDL with two different antigens on formation and development of atherosclerosis
... to oxidized LDL (ox-LDL) as one of the main immunogenes which have important roles in primary lesions of atherosclerosis ...in LDL strongly converted it to immunogenic par- ticle. ...
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Cellular signalling by tissue factor and lipoproteins in the pathogenesis of atherosclerosis
... of LDL since oxidative changes in vitro only occur if the media contains trace amounts of metal ...that LDL oxidation by endothelial cells and macrophages is dependent on the appearance of thiol in medium ...
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Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene
... acetyl LDL and oxidized LDL by these ...of oxidized LDL by Kupffer cells from wild-type animals was high (25–30 m g/mg/5 h), and was similar to that of acetyl LDL in these cells ...
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Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids
... Mitophagy is a critical cellular process that selectively targets damaged mitochondria for autophagosomal degradation both under baseline conditions and in response to stress preventing oxidative damage and cell death. ...
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Effect of Olive Oil Phenolics on Lipidemic Profile and Oxidative Stress in Mice
... (TC) LDL cholesterol, triglycerides, uric acid, TBARS, and oxidized LDL (oxLDL) were ...and LDL were significantly elevated in control groups, while oils rich in phenols restricted further ...
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Protective effect of high density lipoprotein associated paraoxonase Inhibition of the biological activity of minimally oxidized low density lipoprotein
... that oxidized phospholipids in mildly oxidized LDL (MM-LDL) produced by oxidation with lipoxygenase, iron, or cocultures of artery wall cells increase monocyte-endothelial interactions and ...
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Physical activity, high density lipoprotein cholesterol and other lipids levels, in men and women from the ATTICA study
... A gender interaction was observed between physical activ- ity status and lipid levels of the participants. Particularly, compared to women who reported sedentary life, those who defined as physically active had ...
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Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways
... Klotho, which is a kind of anti-aging protein [9], is in- volved in various pathologies, such as atherosclerosis, heart damage, hypertension, acute kidney injury, chronic kidney disease, diabetes mellitus, and even ...
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Phospholipase D modified low density lipoprotein is taken up by macrophages at increased rate A possible role for phosphatidic acid
... of LDL leads to cellular cholesterol accumulation. Upon incubation of LDL with phospholipase D (PLase D), a time- and enzyme dose- dependent production of phosphatidic acid (PA), paralleled by a rapid ...
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Relationship of oxidized low density lipoprotein with lipid profile and oxidative stress markers in healthy young adults: a translational study
... Interestingly, ox-LDL concentrations were higher in the subjects included in the higher tertile of GPx activity (Figure 1), independent from gender, age, smoking sta- tus, physical activity, truncal fat, ...
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Oxidized low density lipoprotein, stem cells, and atherosclerosis
... of ox-LDL and the thera- peutic effects of antioxidant agent ...oxidative LDL modification and foam cell transformation of macro- phages ...stress, ox-LDL could in- duce endothelial ...
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Apolipoprotein-J blocks increased cell injury elicited by ox-LDL via inhibiting ROS-CaMKII pathway
... cyte apoptosis. ApoJ has also been reported to decrease intracellular ROS levels in human corneal endothelial cells and retinal pigment epithelial cells [22, 23]. We have previ- ously shown that adenovirus-mediated ApoJ ...
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