Oxidized Low-Density Lipoprotein
Pro-inflammatory Cytokines and Oxidized Low-Density-Lipoprotein in Patients With Fibromyalgia
... Objectives: This study aims to evaluate the differences in serum levels of tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), (IL-8), and oxidized low-density lipoprotein[r] ...
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The Effect of Adiponectin on Osteonectin Gene Expression by Oxidized Low Density Lipoprotein-Treated Vascular Smooth Muscle Cells
... Osteonectin is a bone- associated protein involved in vascular calcification. Adiponectin may protect against cardiovascular disease but possible effects on vascular calcification have been poorly studied. The aim of ...
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Regulation of G protein alpha i2 subunit expression by oxidized low density lipoprotein
... Oxidized low-density lipoprotein (LDL) inhibits signalling pathways mediated by pertussis toxin-sensitive guanine nucleotide-binding proteins (Gi ...with oxidized LDL (0-100 ...
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Comparison of lipid profile parameters and oxidized low-density lipoprotein between normal and preeclamptic pregnancies in a tertiary care hospital in Nepal
... Introduction: Preeclampsia is a pregnancy-specific complication that significantly contributes to maternal and perinatal morbidity and mortality worldwide, even more so in developing countries such as Nepal. The ...
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Effect of Glycemic Control on Plasma Oxidized Low Density Lipoprotein Levels in Diabetics
... enhanced low-density lipoprotein (LDL) glycosylation [4] and glycated LDL is considered to be oxidized more easily than intact LDL [5, 6, 7, ...8]. Oxidized low-density ...
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Oxidized low density lipoprotein, stem cells, and atherosclerosis
... and low density lipoprotein cholesterol (LDL-C) are among the firmly established risk factors of CAD ...of oxidized low density lipoprotein (ox- LDL) increased in CAD ...
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Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein
... of oxidized PL, or neoepitopes generated by ad- duct formation between breakdown products of oxidized PL and associated ...to oxidized low density lipoprotein, showed a striking ...
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Relationship between oxidized low-density lipoprotein antibodies and obesity in different glycemic situations
... to oxidized low-density lipoprotein (oxLDL) are a heterogeneous group of antibodies that are controversially discussed to be either pathogenic or ...
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Effect of platelet activating factor acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein
... Mildly oxidized low density lipoprotein (MM-LDL) produced by oxidative enzymes or cocultures of human artery wall cells induces endothelial cells to produce monocyte chemotactic protein-1 and ...
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Statin therapy reduces oxidized low density lipoprotein level, a risk factor for stroke outcome
... high density lipoprotein; hs-CRP: high- sensitivity C-reactive protein; LDL: low density lipoprotein; MRA: magnetic resonance angiography; MRI: magnetic resonance imaging; mRS: modified ...
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Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low density lipoprotein and exhibit decreased activity of the lipoprotein associated phospholipase A2
... ERA patients were treated with methotrexate (0.2 mg/kg/ week), and prednisone (7.5 mg/day). The dose of methotrex- ate remained stable during the study, while the dose of pred- nisone was tapered to 5 mg/day according to ...
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Role of lysophosphatidylcholine in the inhibition of endothelial cell motility by oxidized low density lipoprotein
... high density lipoprotein (13) have been shown to increase reendo- thelialization of in vitro wounds by stimulating EC prolifera- ...high density lipoprotein, and to a lesser extent LDL, ...
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Role of oxidized low density lipoprotein in atherogenesis
... However, 15-lipoxygenase activity in cultured endothelial and smooth muscle cells appears to play a dominant role in the ability of these cells to oxidatively modify LDL 10, and recent d[r] ...
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Inhibition of lectin like oxidized low density lipoprotein receptor 1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats
... OxLDL itself has also been well known to play a key role in the adherence of monocytes to the activated endothelium. Possible intracellular processes include activation of protein kinase C, mitogen-activated protein ...
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Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages
... Deficient processing of apo B in oxidized LDL (ox-LDL) by macrophage lysosomal proteases has been documented and attributed to modifications in apo B. We have investigated whether direct inactivation of lysosomal ...
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The effect of oxidized low-density lipoprotein combined with adriamycin on the proliferation of Eca-109 cell line
... the low end (mainly due to cancer) ...that low dose oxLDL has bilateral adjustment characteristics on the prolifera- tion of quiescent human fibroblasts and rabbit smooth muscle ...
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High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARγ/CD36 Pathway in Inflammatory Adipocytes
... The proinflammatory cytokines interleukin-8 (IL-8) and interleukin-6 (IL-6) play an important role in cell proliferation, survivals, and metabolism. The effects of HDL on release of IL-8 and IL-6 were ex- amined by ...
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The association between oxidized low-density lipoprotein antibodies and hematological diseases
... The IgG and IgM antibodies are produced mainly due to the modification forms of oxLDL, malondialdehyde- modified LDL (MDA-LDL) and advanced glycosylation end product-modified LDL (AGE-LDL) [32]. Freigang S. et al. found ...
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Protective effect of high density lipoprotein associated paraoxonase Inhibition of the biological activity of minimally oxidized low density lipoprotein
... that oxidized phospholipids in mildly oxidized LDL (MM-LDL) produced by oxidation with lipoxygenase, iron, or cocultures of artery wall cells increase monocyte-endothelial interactions and this sequence of ...
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High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes
... important. Oxidized low density lipoprotein (OxLDL) is a known acti- vator of monocytes which are involved in the pathogenesis of ...of oxidized lipids, we hypothesized that OxLDL could ...
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