oxygen-sensing
Proteomic analysis reveals diverse proline hydroxylation- mediated oxygen-sensing cellular pathways in cancer cells
... regulating oxygen-response pathways in tumor initiation and ...cellular oxygen-sensing pathways and revealed potentially new targets that dynamically respond to hypoxia microenvironment in tumor ...
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Hydrogen sulfide and oxygen sensing: implications in cardiorespiratory control
... particular sensing mechanism as there are arguments for ...in oxygen: will the real sensor please stand up?’ (Kemp, 2006), ‘Hypoxic pulmonary vasoconstriction: mechanisms and controversies’ Aaronson et ...
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Oxygen sensing, hypoxia inducible factor 1 and the regulation of mammalian gene expression
... match oxygen supply to cellular metabolism and appear likely to involve the regulation of gene expression by ...specific oxygen sensing mechanism, perhaps involving a haem protein in a ...
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Significance of KATP channels, L-type Ca2+ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles In vivo
... in oxygen sens- ing does not indicate that the change in influx is medi- ated by changes in the membrane ...the oxygen sensing mechanism, but they do not allow us to discriminate between a direct ...
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A Role for Sterol Levels in Oxygen Sensing in Saccharomyces cerevisiae
... oxidase (M oraes et al. 2004). Because cytochrome C oxidase is thought to play a role in oxygen sensing and the activation of some hypoxically expressed genes (K wast et al. 1999), in principle, depletion ...
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Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology
... In reference to the aforementioned observation [78] some recent concepts on oxygen sensing mechanisms at the ca- rotid body chemoreceptors have been highlighted [1,79]. Most available evidence suggested ...
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HIF hydroxylation and the mammalian oxygen sensing pathway
... The study of the interaction of pVHL with HIF has led to new insights into the mammalian oxygen-sensing pathway and has demonstrated a heretofore unappre- ciated role for enzymatic protein hydroxylation in ...
6
Oxygen sensing coordinates photomorphogenesis to facilitate seedling survival
... of oxygen sensing controlling early seedling devel- opment, we tested the ability of individual ERFVIIs to repress hook opening by expressing mutant stable versions (in which Cys-2 was changed to Alanine, a ...
7
Developmental vascular pruning in neonatal mouse retinas is programmed by the astrocytic oxygen sensing mechanism
... the oxygen-sensing mechanism controls vascular pruning by regulating astrocyte ...abundance. Oxygen from the nascent vascular plexus may activate PHD2 in nearby astrocytes, leading to the ...
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Abstract This thesis is mainly to study the oxygen sensing characteristics of gallium metal oxide film at high temperature, and to
... the oxygen sensing characteristics of gallium metal oxide film at high temperature, and to analyze the oxygen sensing at temperatures above ...under oxygen, a simple Wheatstone bridge ...
7
Oxygen sensing and the transcriptional regulation of oxygen responsive genes in yeast
... From the preceding discussion, it is clear that heme works together with a variety of trans-acting factors to regulate the transcription of oxygen-responsive genes in yeast. Further evidence for the central role ...
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Mammalian oxygen sensing, signalling and gene regulation
... of oxygen is essential to all higher organisms because it serves as the terminal electron acceptor in mitochondrial oxidative phosphorylation and because several enzymatic processes require molecular oxygen ...
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A comparative analysis of putative oxygen sensing cells in the fish gill
... may be detected where the lamellar, filament, or gill raker epithelium is exposed to the ambient water. Oxygen-sensing cells at these different sites could also be either chemoreceptive or paracrine. A ...
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Aerosol-deposited BaFe 07 Ta 03O for nitrogen monoxide and temperature-independent oxygen sensing
... The oxygen sensing properties of BFT30 thick films were investigated by varying gradually the oxygen partial pressure from 10 −2 to 1 bar at a fixed ...The oxygen con- centration was held for ...
7
Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo
... tissue oxygen availability is severely limited, oxygen dependent regulation of the balance between innate immune responses and bacterial virulence and replicative capacity may be critical in defining the ...
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Acute Oxygen Sensing-Inching Ever Closer to an Elusive Mechanism
... Aguera et al, published in this issue (Fernandez-Aguera et al., 2015), places mitochondria firmly centre stage and, crucially, points to complex I of the electron transport chain as being a key element for oxygen ...
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Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors
... and rapid adaptation to changes in the partial pressures of inspired atmospheric gases is crucial to survival. During episodes of compromised O 2 availability, numer- ous chemosensory systems, acting in concert, rapidly ...
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Cellular oxygen sensing need in CNS function: physiological and pathological implications
... that oxygen-dependent gene expression is of crucial importance in governing essential steps of neurogenesis such as cell proliferation and renewal, survival and ...Low oxygen concentrations have been shown ...
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Faulty oxygen sensing disrupts angiomotin function in trophoblast cell migration and predisposes to preeclampsia
... low oxygen contributes to the impaired trophoblast migration/invasion seen in PE (10, ...3% oxygen and standard 21% normoxic ...3% oxygen exhibited a significantly reduced AMOT and PAR6 interaction ...
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Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal <em>Trichoplax adhaerens</em>
... hypoxia sensing in higher animals was therefore of interest from a broad evolutionary ...hypoxia sensing mechanisms, as well as 2OG oxygenases and related ...
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