PAMAM dendrimer
Synthesis, characterization and evaluation of Pamam Dendrimer-Gold complex as an anion recognition material
... study, PAMAM dendrimer was successfully synthesized by a divergent synthesis route using the reagent excess method starting from ethylenediamine (EDA) followed by consecutive Michael addition and ester ...
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Photosensitizer and peptide-conjugated PAMAM dendrimer for targeted in vivo photodynamic therapy
... of PaMaM dendrimer particles To study the cellular uptake of PAMAM dendrimer by SK-OV-3 cells, free PS, DPN, and ADPN (DPN with Affibody) were added at an equivalent PS concentration of 2 µ ...
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FOLATE ANCHORED CONJUGATES OF POLY (AMIDOAMINE) (PAMAM) DENDRIMER FOR CONTROLLED SITE SPECIFIC DELIVERY OF PIROXICAM IN ARTHRITIC RATS
... G4.0-PAMAM dendrimer and PBS (pH 7.4) solution of folate-dendrimer conjugates in screw- capped vials (10 ...4.0 PAMAM dendrimer-piroxicam complex was coded PXM-D1 and drug loaded ...
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The influence of heterocyclic compound-PAMAM dendrimer complexes on evoked electrical responses in slices of hypoxic brain tissue
... the PAMAM dendrimer with compound 2 ...the PAMAM dendrimer with compound 1 (Figs 1A and ...with dendrimer-based complexes, a brief upturn in PS amplitude was always present, reflecting ...
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Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro
... of PAMAM colocalization in mitochondria increased from ...higher dendrimer concentrations, which is consistent with their cytotoxic effect (Figures 2 and ...BC- PAMAM dendrimer signal ...
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<p>A 3D-Printed Multi-Chamber Device Allows Culturing Cells On Buckypapers Coated With PAMAM Dendrimer And Obtain Innovative Materials For Biomedical Applications</p>
... after PAMAM absorption, some speci fi c spectral changes were observed (magni fi cations in Figure 3B – ...nated PAMAM G0 dendrimer, both by Raman 20 and IR 21 spectroscopy, so that the effect can be ...
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<p>PAMAM Dendrimer Nanomolecules Utilized as Drug Delivery Systems for Potential Treatment of Glioblastoma: A Systematic Review</p>
... the dendrimer (ie, PEG), they also conjugated a peptide to help facilitate increased speci fi city for cancer ...G5 PAMAM dendrimer for a glioma-targeted delivery system ...the PAMAM ...
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Selective aggregation of PAMAM dendrimer nanocarriers and PAMAM/ZnPc nanodrugs on human atheromatous carotid tissues: a photodynamic therapy for atherosclerosis
... of PAMAM dendrimers [76], it was noted that the drying procedure could induce the for- mation of aggregates by capillary forces and, therefore, in- fluence the relative positions of the deposited ...G1 ...
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Evaluation of Biotinylated PAMAM Dendrimer Toxicity in Models of the Blood Brain Barrier: A Biophysical and Cellular Approach
... biotinylated PAMAM dendrimers on the DPPC domain structure is shown in Figures 3 and ...G4 PAMAM dendrimer concentrations, DPPC:G4, 2:1 (Figure 3(A)), some regions look similar to DPPC alone, with ...
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A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system
... The quantitative analysis of the apoptosis activity in control, and treated with different ATO formulations, was measured by flow cytometry. FITC dye and PI were used to label and differentiate between live, apoptotic ...
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Characterization of Co(II)-PAMAM dendrimer complexes with polypropylene oxide core by using UV-VIS spectroscopy
... The CEM Focused Microwave™ Synthesis System, Model Discover (CEM Corporation, North Carolina, USA) with a continuous microwave power delivery system with the operator selectable power output from 0–300 watts (± 30 watts) ...
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Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles
... polyamidoamine dendrimer (PD), an unmodified plain type of PD, has the obvious disadvantage of cytotoxicity, but still serves as an attractive molecule because it easily adheres to the cell surface, facilitating ...
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“Dendrimer” by Sadhana R Shahi, Mitali S Kulkarni, Gopal S Karva, Prabhanjan S Giram, Ruchika R Gugulkar, India.
... 1. PAMAM dendrimer complex with ...G5 PAMAM dendrimer and showed ...of PAMAM dendrimers by using indomethacin as the model drug in transdermal drug application was reported to be ...
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<p>Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury</p>
... G6 PAMAM dendrimer did not signi fi cantly exacerbate recovery of cardiac function (with the exception of CF) beyond ischemia ...G6 PAMAM dendrimer cannot have any addi- tional detrimental ...
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Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity
... 3 PAMAM and generation 4 PPI ...3 PAMAM showed better performance in solubilization and release of phenylbutazone molecules than did generation 4 PPI with the same number of sur- face amine ...PPI ...
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Computation on Zagreb Polynomial of Some Families of Dendrimers
... of dendrimer nanostars known as PAMAM dendrimer with trifunctional core unit by construction of dendrimers generations with growth ...shows PAMAM dendrimer of the generations with three ...
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PAMAM Dendrimers mediated solubility enhancement of poorly soluble drugs: a concise review
... 31. Devarakonda, B., Hill, R.A., DeVilliers, M.M. The effect of PAMAM dendrimer generation size and surface functional groups on the aqueous solubility of nifedipine. Int J Pharm, 2004, 284:133-40. 32. ...
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Synthesis, characterization and antibacterial activity of colloidal silver nanoparticles encapsulated in low generation poly(amido)amine dendrimers
... synthesized PAMAM indicated that some structural defects were present in the form of missing –NH groups presumably due to incomplete amidation or intramolecular cyclization of terminal amino ...of PAMAM- ...
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Anion recognition properties of poly(amidoamine) dendrimer functionalized with hamilton receptor moiety in aqueous solutions containing nitrate and nitrite ions
... the PAMAM dendrimer. Lastly, the modified PAMAM dendrimers are reacted with inorganic anions and the binding affinity is ...The PAMAM dendrimer, Hamilton receptor and Hamilton ...
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A Novel Nanofiltration Membrane Prepared with PAMAM and Graphene oxide for Desalination
... most-studied dendrimer is probably the so-called poly(amidoamine) (PAMAM) dendrimer, which has a global shape containing much higher amino group densities on the surface than conventional ...of ...
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