Paraneoplastic Syndromes
Evidence that tumor necrosis factor plays a pathogenetic role in the paraneoplastic syndromes of cachexia, hypercalcemia, and leukocytosis in a human tumor in nude mice
... Recently, we have established a human squamous cell carcinoma of the maxilla (called MH-85) associated with hypercalcemia, leukocytosis, and cachexia in culture. MH-85 tumor cells caused the same paraneoplastic ...
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Worsening and newly diagnosed paraneoplastic syndromes following anti-PD-1 or anti-PD-L1 immunotherapies, a descriptive study
... Paraneoplastic syndromes (PNSs) are rare autoimmune disorders associated with cancer [7, ...these syndromes is mediated by either sol- uble factors (such as hormones or cytokines secreted by the ...
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Immunopathogenesis of ophthalmological paraneoplastic syndromes: Recent findings
... The tumor during its neoplastic transformation can de- velop some antigens similar to those naturally occurring in different organs. Human immune system tries to pro- tect the organism via humoral or cellular response ...
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Endocrine paraneoplastic syndromes in patients with neuroendocrine neoplasms
... In this study, the prevalence of the EPNS secondary to a variety of NENs as obtained from the Greek NEN database (EKPA-Laiko) was found to be 1.9% and included fi ve different syndromes. In contrast, EPNS was more ...
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Unusual Paraneoplastic Presentation of Cholangiocarcinoma
... Paraneoplastic syndromes demonstrate the complex interac- tion between the immune system and ...Various paraneoplastic cutaneous manifestations of cholangiocarcinoma have been reported, such as ...
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Severe paraneoplastic hypereosinophilia in metastatic renal cell carcinoma
... various paraneoplastic syndromes such as hypercalcemia, hypertension and ectopic hormone production ...a paraneoplastic syndrome in several solid and hematolo- gical ...severe paraneoplastic ...
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Paraneoplastic Manifestations Of Lymphoma
... Introduction- Paraneoplastic syndromes (PNS) are a group of clinical disorders associated with an underlying malignant disease that are not directly related to the physical effects of the primary or ...
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Paraneoplastic neurological complications of breast cancer
... other paraneoplastic syndromes is mediated by aberrant immune cross-recognition of anti- ...adaption. Paraneoplastic retinopathy is most associated with melanoma and small cell lung cancer but it has ...
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Clinical Reasoning: A man with rapidly progressive weakness and respiratory failure
... Noninfectious etiologies, such as sarcoidosis, Behçet disease, Sj¨ogren syndrome, systemic lupus erythematosus, neuromyelitis optica, and lymphoma, and paraneoplastic syndromes, such as anti-Hu and anti-Ma2 ...
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Paraneoplastic neurological syndromes
... Almost any part of the nervous system can be affected by paraneoplastic syndromes (table 1). It is important to recognise paraneoplastic neurological syndromes (PNS), for several reasons. They ...
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Neuroacanthocytosis Syndromes
... malabsorption. The latter disorders are characterized by a peripheral neuropathy and sensory ataxia due to dorsal column degeneration, but movement disorders and cognitive impairment are not present. NA syndromes ...
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Current controversies in states of chronic unconsciousness
... DIAGNOSTIC ISSUES The vegetative state (VS) and minimally conscious state (MCS) are the principal clinical syndromes of patients with chronically disordered consciousness. As syndromes, [r] ...
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Saka: A Culture-Specific Disorder in Malaysia and its Emic and Etic Patterns
... culture-bound syndromes are generally limited to specific societies or culture areas and are localized, folk, diagnostic categories that frame coherent meanings for certain repetitive, patterned, and troubling set ...
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The Lissencephalic Syndromes
... The Lissencephalic Syndromes The Lissencephal~c Syndromes M K Thong, MPaeds, C T Lim, FRCp, M T Koh, MRCp, G G Kumar, FRCR*, Department of Paediatrics, *Department of Radiology, Faculty of Medicine, U[.] ...
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Remission of nephrotic syndrome after surgical intervention for bronchogenic carcinoma: the 10-year follow-up of a patient with membranous nephropathy
... from paraneoplastic NS due to MN in patients who achieve favorable long-term survival after the successful removal of malignant ...for paraneoplastic NS, are ...
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Syndromes of the First and Second Branchial Arches, Part 2: Syndromes
... congenital syndromes affecting the face occur due to defects involving the first and second ...these syndromes. The radiologic evaluation of syndromes of the first and second BA should begin first by ...
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Efficacy of rituximab in non-paraneoplastic autoimmune retinopathy
... Table 2 Rituximab treatment details and responses Case Indication Rtx induction dosage Rtx maintenance dosage ERG response Visual field after Rtx OCT of the macula Visual acuity Atb resu[r] ...
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Chromosomal phenotypes and submicroscopic abnormalities
... Parental submicroscopic inversion polymorphisms between the LCRs flanking the microdeletion regions have recently been demonstrated to be present in several microdeletion syndromes. An inversion polymorphism on ...
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Hypereosinophilic syndromes
... • Myeloproliferative-HES (M-HES) may be used for patients with an array of clinical and biological features suggesting the possible existence of an underlying myelo- proliferative disord[r] ...
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Human autoantibodies against desmoplakins in paraneoplastic pemphigus
... paraneoplastic pemphigus has been described. Paraneoplastic pemphigus is associated with lymphoid malignancies, thymomas, and poorly differentiated sarcomas. Serum of affected patients contain pathogenic ...
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