Partial epilepsy
A review of safety and efficacy of zonisamide for treatment of pediatric partial epilepsy
... some methodological drawbacks, our review of available literature supports the view that adjunctive zonisamide therapy is effective and well tolerated in pediatric patients with refractory partial epilepsy, ...
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The Localizing and Lateralizing Value of Auras in Lesional Partial Epilepsy Patients
... Patients were identified who had visited the outpatient epi- lepsy clinic of Severance Hospital between 2000 and 2007 and had lesions confined to a single lobe based on MRI re- sults. All subjects had scalp EEGs and ...
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Monotherapy for partial epilepsy: focus on levetiracetam
... refractory partial epilepsy have demonstrated the effi cacy of LEV as adjunctive therapy, with a responder rate ( 50% reduction in seizure frequency) of ...refractory epilepsy, and its effectiveness ...
6
Pregabalin in the management of partial epilepsy
... Pregabalin was found to be very well tolerated in the initial placebo-controlled adjunctive trials in partial epilepsy. The treatment-related adverse events were mild to moderate, appeared in the beginning ...
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MR in partial epilepsy: value of high resolution volumetric techniques
... can range from grossly dysmorphic to subtly dysmorphic (with fused gyri and minor irregu- larities of the cortex–white matter junction) to grossly normal with microscopic abnormalities of lamination (10 –12). Therefore, ...
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MR imaging in chronic partial epilepsy: role of contrast enhancement
... Therefore , we designed a prospective study to determine the efficacy of routine administration of gadopentetate dimeglumine in a large population of patients with partial seizures refer[r] ...
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Determination of SCN1A genetic variants in Mexican patients with refractory epilepsy and Dravet syndrome.
... including epilepsy, autism, and ...myoclonic epilepsy of infancy (SMEI), as well as epileptic encephalopathy, partial epilepsy, generalized epilepsy, and febrile seizures (Meng et ...
5
Profile of perampanel and its potential in the treatment of partial onset seizures
... Overall, these three Phase-III RCTs demonstrated the clinical efficacy of adjunctive once-daily PER 4 mg/day, 8 mg/day and 12 mg/day in adult drug-resistant partial epilepsy (Figure 1C). In contrast, PER 2 ...
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Comparison of the health-related quality of life between epileptic patients with partial and generalized seizure.
... consciousness during seizure attacks and this may decrease the chance of getting hurt. Moreover, many patients with partial epilepsy do not experience severe seizure attacks. Hence, it is possible that they ...
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Depression and anxiety in patients with epilepsy
... in partial epilepsy than generalized ...with partial epilepsy, there is a higher propensity of developing aura leading to anticipatory ...
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Update on treatment of partial onset epilepsy: role of eslicarbazepine
... Abstract: Partial epilepsy comprises simple partial seizures, complex partial seizures, and secondarily generalized seizures, and covers more than 60% of patients with ...for epilepsy ...
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Child Neurology: Epilepsy of infancy with migrating focal seizures
... tially shows diffuse slowing of background activity and frequent slow waves, which often shift from one hemisphere to the other. Multifocal discharges origi- nating from both hemispheres are also frequently noted. The ...
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Clinical utility of implantable neurostimulation devices as adjunctive treatment of uncontrolled seizures
... refractory partial epilepsy, and after 1 month the patients were randomized to receive either stimula- tion in response to seizure activity (treatment group) or no stimulation (control ...
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MR detection of hippocampal disease in epilepsy: factors influencing T2 relaxation time
... RESULTS: In the 55 patients with partial epilepsy, hippocampal T2 relaxation times did not correlate with seizure frequency , duration of epilepsy , or age, but they were significantly m[r] ...
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Update on the role of eslicarbazepine acetate in the treatment of partial-onset epilepsy
... complex partial seizures, partial seizures with secondary generalization, syncope, spontaneous abor- tion, drug rash with eosinophilia, and systemic ...
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Post Stroke Epilepsy within a Teaching Hospital in Cotonou, Benin
... Benin. It involved 35 patients brought together through comprehensive sam- pling. Vascular epilepsy hospital attendance rate was 2%. There were simple partial seizures in 74.28% of cases while cerebral ...
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Neuroimaging in Children With Newly Diagnosed Epilepsy: A Community-Based Study
... On multivariable analysis with logistic regression, an abnormal motor examination was the strongest predictor of abnormal imaging (odds ratio [OR]: 18.9; 95% confidence interval (CI): 9.9, 36.3; P ⬍ .0001). After ...
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A descriptive analysis of drug treatment patterns and burden of illness for pediatric patients diagnosed with partial-onset seizures in the USA
... claim does not necessarily mean a drug was taken as pre- scribed, and some patients may receive drugs without a prescription claim (eg, by receiving samples). Claims data do not contain information on disease severity, ...
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New developments in the management of partial-onset epilepsy: role of brivaracetam
... untreatable epilepsy (431 had focal epilepsy and 49 had primary generalized ...focal epilepsy, both the baseline- adjusted percent reduction in BRV over PBO group and the median percent reduction in ...
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Advancing epilepsy genetics in the genomic era
... of epilepsy, in which mutations in different genes cause syndromes that are clinically indistinguishable, and mutations in a sin- gle gene, such as SCN1A, can cause a range of phenotypes varying from febrile ...
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