Partition coefficient (KD)
Computational approaches to the predication of the octanol water partition coefficient (LogPo/w)
... n-octanol/water partition coefficient of anti-cancer ...of partition coefficient drug concentration ratios (log P) in humans is not possible, and to do so in animal models is expensive and ...
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Effective Parameters on the Partition Coefficient of Guanidine Hydrochloride in the Poly (Ethylene Glycol) +Phosphate +Water System at 298.15 K
... of guanidine hydrochloride on phase behavior of PEG4000/ phosphate/ guanidine hydrochloride/ water at different guanidine hydrochloride concentrations and pH were investigated [13]. In the present study the ...
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DFT Based QSAR Prediction of 1 Octanol/Water Partition Coefficient of Adamantine derivatives drugs
... to predict the response of additional chemicals. Validating QSAR with external data (i.e. data not used in the model development), although demanding, is the best method for validation [8-9]. However the availability of ...
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Phase equilibrium and partition coefficient of selected pesticides and nitrophenols in double and triple-phase liquid-phase microextraction
... of partition coefficient and analysis of selected pesticides and nitrophenols in water ...the partition coefficient for the selected analytes that were found to be directly correlated to the ...
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QSAR Study of the octanol/water partition coefficient of organophosphorus compounds: The hybrid GA/MLR and GA/ANN approaches
... The QSAR method was applied to the prediction of the octanol/water par- tition coefficient of organophosphorous insecticides. The validation techniques, including leave-one-out cross validation, randomization ...
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The protein binding substance Ibuprofen does not affect the T1 time or partition coefficient in contrast enhanced cardiovascular magnetic resonance
... We hypothesized that the protein bound fraction might be smaller and subsequently relaxivity lower resulting in longer T1 times for myocardium and blood post contrast administration when another drug with protein binding ...
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Anatomic applications of xenon enhanced CT scanning: visual image analysis and brain blood partition coefficient studies in man
... When the arterial blood and brain concentration s of xenon are measured by CT , a reasonably accurate assessment of regional cerebral blood flow and brain-blood partition coefficient ,\ [r] ...
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Computational approaches to the prediction of the 1 octanol/water partition coefficient of benzimidazole derivatives drugs
... octanol–water partition coefficient is a measure of the hydrophobicity and hydrophilicity of a ...n-octanol/water partition coefficient of anti-cancer ...of partition coefficient ...
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SHORT COMMUNICATION: ESTIMATION AND QUANTITATIVE PREDICTION OF PARTITION COEFFICIENT OF SOME BENZOGLYCOLAMIDE ESTERS
... A major goal of Quantitative Structure Property Relationship (QSPR) studies is to find a mathematical relationship between the activity and property under investigation e.g. solubility, LogP, pKa, molar refraction, ...
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QSAR PREDICTION OF N-OCTANOL/WATER PARTITION COEFFICIENT FOR POLYCHLORINATED BIPHENYLS
... n-octanol/water partition coefficient (logKow) is a very important property which concerns water-solubility, bioconcentration factor, toxicity and soil absorption coefficient of organic ...
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QSPR study on the octanol/air partition coefficient of polybrominated diphenyl ethers by using molecular distance-edge vector index
... octanol/air partition of PBDEs may influence their fate, transport, and transformation in atmospheres ...tition coefficient (K OA ), which is defined as the ratio ...
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A comparison of log Kow (n-octanol–water partition coefficient) values for non-ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods
... coefficient; OECD: Organisation for Economic Co‑operation and Development; QSPR: quantitative structure–property relationship; HPLC: high performance liquid chromatography; TGD: Technical Guidance Document; CMC: ...
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Effects of Salinity, pH and Temperature on the Octanol-Water Partition Coefficient of Bisphenol A
... provides partition coefficients by calculation from the inherent chemical and physical properties of the compound, without taking environmental conditions into ...the partition coefficients experimentally ...
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The blocks of the partition algebra in positive characteristic
... the partition algebra P n F (δ), when δ lies in the prime subfield of F , in terms of the action of an affine reflection group of type ...the partition algebra, we show here that the description of the ...
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Reconstitutions of plasmid partition systems and their mechanisms
... For 283 Walker-type partition system, the in vitro reconstitutions of plasmid transport by ParA 284 gradient, the lack of ParA filaments in vivo and the localization of partition complex[r] ...
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Chapter II. Consequences of Partition
... The partition is such a monumental tragedy where the ego clash between these communities led not only to the brutal deaths of millions of people during the vehemence, but also the on-going subsequent conflicts ...
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Stability in a ball partition problem
... we partition a ball into three regions of equal ...particular partition given by three half-disks sharing the line segment − 1 ≤ x ≤ 1, y = 0, z = 0 in their boundaries and meeting at angles of ...
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Intrinsic energy partition in fission
... Excepting the strong fluctuations related to the large mass asymmetries, the results agree qualita- tively well with the data that correspond to neutron multiplicities. It is a first microscopic description of the ...
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Bootstrapping the S5 partition function
... vortex partition function, and it turns out that the generating function of the defect theory also satisfies analogous constraints ...Ω-background partition function can be naturally assembled from lower ...
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Partition, migration, and jute cultivation in India
... If we are to use India's experience with jute after partition to learn about present migrations, we must establish that future migrants will face similar opportunities. In particular, our results suggest that ...
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