Pathogen-associated molecular pattern
Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length
... Despite the introduction of direct-acting antiviral (DAA) drugs against hepatitis C virus (HCV), infection remains a major pub- lic health concern because DAA therapeutics do not prevent reinfection and patients can ...
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Listeria monocytogenes-Derived Listeriolysin O Has Pathogen-Associated Molecular Pattern-Like Properties Independent of Its Hemolytic Ability
... There is a constant need for improved adjuvants to augment the induction of immune responses against tumor-associated anti- gens (TAA) during immunotherapy. Previous studies have established that listeriolysin O ...
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The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll Like Receptor Related TRAF3 Independent Mechanism
... intracellular pattern recognition receptors (PRRs) reside in either the endolysosome or the cytoplasm to sense pathogen-derived RNAs, DNAs, or synthetic analogs of double-stranded RNA (dsRNA), such as ...a ...
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Chp8, a Diguanylate Cyclase from Pseudomonas syringae pv Tomato DC3000, Suppresses the Pathogen Associated Molecular Pattern Flagellin, Increases Extracellular Polysaccharides, and Promotes Plant Immune Evasion
... plant pathogen Pseudomonas syringae causes disease in a wide range of ...The associated decrease in crop yields results in economic losses and threatens global food ...the pathogen, the basic ...
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Identification of the RNA Pseudoknot within the 3′ End of the Porcine Reproductive and Respiratory Syndrome Virus Genome as a Pathogen-Associated Molecular Pattern To Activate Antiviral Signaling via RIG-I and Toll-Like Receptor 3
... detect pathogen-associated molecular patterns (PAMPs) on viral nucleic acid by host pattern recognition receptors (PRRs) to initiate the antiviral ...
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Dissecting the molecular interactions between wheat and the fungal pathogen Zymoseptoria tritici
... the molecular events that occur during ...the pathogen-associated molecular pattern-triggered immunity (PTI) layer of plant defense, and (2) major Stb loci for resistance against ...the ...
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Protective effect of the methanol extract from Cryptotaenia japonica Hassk against lipopolysaccharide induced inflammation in vitro and in vivo
... PAMP: Pathogen-associated molecular pattern; DAMP: Danger-associated molecular pattern; IFN- γ : Interferon- γ ; NK cells: Natural killer cells; LPS: Lipopolysaccharide; ...
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Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons
... critical role in the neuroimmune link between T helper 2 cells and sensory neurons for the generation of T-cell medi- ated itch, was evidenced in a small subpopulation of IL- 31RA(+)/TRPV1(+)/TRPA1(+) neurons [90]. In ...
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Muramyl Dipeptide Synergizes with Staphylococcus aureus Lipoteichoic Acid To Recruit Neutrophils in the Mammary Gland and To Stimulate Mammary Epithelial Cells
... major pathogen for the mammary gland of dairy ruminants, elicits the recruitment of neutrophils into milk during mastitis, but the mechanisms are incompletely ...bial-associated molecular ...
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Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection
... by pattern recognition receptors (PRRs) that recognize virus-conserved pathogen-associated molecular patterns (PAMPs) to initiate innate immune ...
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The role of inflammation and interleukin-1 in acute cerebrovascular disease
... by molecular motifs expressed by pathogens termed pathogen associated molecu- lar patterns, or by molecules released from dead or injured tissue/cells, or that are modified during disease called dam- ...
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COPD disease severity and innate immune response to pathogen-associated molecular patterns
... the pattern of associations for two alternative hypotheses: 1) severe dis- ease is associated with increased cytokine production; and 2) severe COPD is associated with reduced cytokine production ...
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C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map
... PRRs, pattern recognition receptors; PAMPs, pathogen-associated molecular patterns; DAMPs, damage-associated molecular patterns; TLRs, Toll-like receptors; NLRs, NOD-like ...
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Role of toll-like receptors in human iris pigment epithelial cells and their response to pathogen-associated molecular patterns
... Expression of TLRs has been reported in a number of ocular tissues such as cornea, conjunctiva, sclera and retina [10-14]. Studies have emphasized the importance of the LPS receptor complex (TLR4 and co-receptors CD14 ...
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Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy
... through pattern recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs) and lead to the production of interferon and proinflammatory cyto- ...
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Characterization and Management of the Race Structure of Phytophthora parasitica var. nicotianae
... Survival Experiment. A microplot experiment was established in May 2000 at the Central Crops research station in Clayton, NC, and continued through the spring of 2003. Plots were infested with either race 0 or race 1 ...
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Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
... example, associated with poor outcome ...and pathogen-associated molecular patterns (PAMPs) has been identified as an early and primary mechanism [2, 31, ...
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Variants in toll like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population
... Different from other pathogens, Mtb infection can persist in the host for long periods in a dormant or latent state, even in a fully functioning immune system [29]. TB immunity is mediated by Th1-type responses; ...
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CD14 Targets Complement Receptor 3 to Lipid Rafts during Phagocytosis of Borrelia burgdorferi
... CR3-and CD14 co-localize to cholesterol-rich microdomains during the phagocytosis of B. burgdorferi. CD14 resides in cholesterol-rich domains or lipid rafts where it recruits surface receptors al- lowing the induction of ...
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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses
... or pathogen invasion) provokes an exaggerated response from microglia and the production of excessive concentrations of neurotoxic molecules, such as nitric oxide, peroxinitrite, prostaglandins, cyclo-oxygenase 2 ...
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