PC12 CELLS
Original Article Eupatilin inhibits OGD/R-induced neuronal injury in PC12 cells
... genes and is important for during neuronal development and under pathological condi- tions including cerebral ischemia [19]. Bcl-2 protein plays an essential role to control the process of cell death through preventing ...
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A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells
... pEGFP-Peripherin cells after NGF induction. There were no detectable TUNEL positive cells found in the cell aggregation of control PC12 cells after 6 days of NGF induction (Figure ...positive ...
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Modulation of H2O2- Induced Neurite Outgrowth Impairment and Apoptosis in PC12 Cells by a 1,2,4-Triazine Derivative
... Neuronal cells are able to sense the surrounding and form branches in response to molecular information from extracellular milieu that in- struct the maturation process and induce neurite regen- eration in these ...
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-induced apoptosis in PC12 cells
... Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by extracellular de- posits of beta-amyloid (Aβ) and neuronal loss. In this study, we evaluated the protective effects and the ...
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Original Article Tempol protect against hypoxia induced oxidative stress in PC12 cells
... in PC12 cell and to explore the underlying mechanisms. Treatment of PC12 cells with hy- poxia reduced viability and increased LDH ...attenuated PC12 cells damage induced by hypoxia with ...
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Induction of apoptosis in catecholaminergic PC12 cells by L DOPA Implications for the treatment of Parkinson's disease
... The hypothesis that L-DOPA therapy in Parkinson's disease may augment neuronal damage and thus accelerate the progression of the disease remains controversial. In this study, we demonstrate that L-DOPA induces death of ...
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Kamishoyosan and Shakuyakukanzoto promote recovery from paclitaxel-induced neurite retraction in PC12 cells
... of cells in the picture was also ...of PC12 cells in differentiation and culture medium for 24 h; following the incubation of differentiated cells with ...in PC12 cells; and fol- ...
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Voltage-Gated Potassium Channel KV1.5 Protects against MPP+ Mediated Neurotoxicity in PC12 Cells
... on PC12 proliferation, and the effect of Kv1.5 on PC12 apoptosis after MPP + treatment in ...of PC12, while transiently knockdown of ...inhibited PC12 proliferation. 2) The effect of Kv1.5 on ...
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Human Corneal Cells and Other Fibroblasts Can Stimulate the Appearance of Herpes Simplex Virus from Quiescently Infected PC12 Cells
... (PC12) cells differentiated with nerve growth factor were infected with HSV-1 strain ...16 cells were ...epithelial cells (HCE) resulted in recovery of virus from most, if not all, clusters of ...
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Taurine protection of PC12 cells against endoplasmic reticulum stress induced by oxidative stress
... PC12 cells were lysed in RIPA buffer (25 mM Tris_HCl pH 7.6, 150 mM NaCl, 1% NP-40, 1% sodium deoxy- cholate, 0.1% SDS) containing 1% (v/v) mammalian pro- tease inhibitor cocktail from Sigma and separated ...
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Expression and purification of recombinant vesicular glutamate transporter VGLUT1 using PC12 cells and High Five insect cells
... In order to further characterize VGLUT1, stable transfectants of VGLUT1-harboring PC12 cells (9) were used for the development of an easy and fast purification protocol. The protocol has three steps: 1) ...
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Characterizing the cytoprotective activity of Sarracenia purpurea L , a medicinal plant that inhibits glucotoxicity in PC12 cells
... The CEI, along with other Canadian First Nations communities, are recognized as some of the highest at- risk populations for T2DM in the world [6,7]. With an average age at diagnosis of just 41 years [8], diabetics also ...
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Chlorogenic acid protects PC12 cells against corticosterone-induced neurotoxicity related to inhibition of autophagy and apoptosis
... PC12 cells were harvested, washed twice with cold phos- phate-buffered saline (PBS), and lysed in RIPA lysis buffer (Beyotime Institute of Biotechnology, Haimen, China) for 30 min on ...
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Original Article Protective effect of bone marrow mesenchymal stem cells on PC12 cells apoptosis mediated by TAG1
... of PC12 cells induced by chronic alcohol ...and PC12 cells could significantly increase PC12 cell activity induced by Aβ 25-35 which was con- sistent with previous report ...and ...
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Original Article Differential gene expression profile analysis in corticosterone-treated PC12 cells
... chromaffin-like cells with nor- adrenergic phenotype through activation of dis- tinct molecular signaling pathways [18, ...Differentiated cells have many properties simi- lar to those of sympathetic neurons ...
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Neurite development in PC12 cells cultured on nanopillars and nanopores with sizes comparable with filopodia
... analysis, cells on substrates were immersed in 1% osmium tetraoxide (OsO4) for 15 minutes, washed in buffered solution, and dehydrated by successive immersion in 10%, 30%, 50%, 70%, 90%, and 100% ethanol for fi ve ...
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<p>Micropatterned nanolayers immobilized with nerve growth factor for neurite formation of PC12 cells</p>
... from that of differentiation in PC12 cells. 48 It is also well known that the differentiation depends on sustained signaling. 49 However, the nerve growth cone exhibits adap- tation through desensitization ...
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THE ROLE OF LACTATE DEHYDROGENASE B IN AEROBIC GLYCOLYSIS- MEDIATED RESISTANCE TO AMYLOID TOXICITY IN PC12 CELLS
... which cells exhibit elevated glycolytic activity and lactate production, while limiting mitochondrial ...resistant PC12 cell lines, derived from a tumour of the rat adrenal medulla, and sought to determine ...
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Cocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells
... Cocaine is a worldwide used drug and its abuse is associated with physical, psychiatric and social problems. The mechanism by which cocaine causes neurological damage is very complex and involves several neurotransmitter ...
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Estrogen Receptor Alpha 36 Gene Knockdown Promote the Expression of NF κB in PC12 Cells
... cultured PC12 cells and to provide an experimental foundation for understanding the function of ER-α36 in nerve ...cells. PC12 cells with ER-α36 expression knocked down by the shRNA ...
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