Pediatric Septic Shock.
Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study
... adult septic patients ...Most pediatric results are rarely specific of septic ...various pediatric intensive care unit (PICU) admission causes (surgery, organ dysfunctions) [11–14], or are ...
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Differential expression of the Nrf2 linked genes in pediatric septic shock
... with septic shock ...between pediatric patients with septic shock within the first 24 h of presentation to the PICU and healthy ...of pediatric septic shock, ...
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Elevated central venous pressure is associated with increased mortality in pediatric septic shock patients
... CVP is affected by cardiac function and blood volume returning to the heart [5, 6], and CVP elevation, which is frequently observed in critically ill patients, is associ- ated with disturbances in venous return and ...
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Differential expression of the nuclear encoded mitochondrial transcriptome in pediatric septic shock
... of pediatric septic shock supports a link between mitochondrial gene expression and clinical outcomes, including organ failure and ...in septic shock through its role in the immune ...
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Translational gap in pediatric septic shock management: an ESPNIC perspective
... cold shock and norepinephrine in or warm ...in pediatric septic shock ...in shock reversal irrespective of hemodynamics [20], no controlled study comparing norepinephrine to dopamine ...
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Genome-Level Longitudinal Expression of Signaling Pathways and Gene Networks in Pediatric Septic Shock
... a septic challenge ...imental septic shock is characterized by widespread T cell apoptosis and that preventing T cell apoptosis positively impacts the outcome of experimental sepsis ...in ...
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High Reliability Pediatric Septic Shock Quality Improvement Initiative and Decreasing Mortality
... To standardize our approach and facilitate early identification, the guideline includes a screening tool/ algorithm (Supplemental Fig 3). All PED patients undergo screening at triage and are assessed throughout their ...
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The glucocorticoid receptor and cortisol levels in pediatric septic shock
... randomized pediatric trial testing the role of corticosteroids in septic shock, perhaps evaluating intra- cellular expression of GCR would be ...
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Identification of pediatric septic shock subclasses based on genome-wide expression profiling
... Based on leave one out cross-validation procedures and subsequent extraction of the top 100 predictor genes, the most distinguishing gene expression signature of the sub- class A patients was repression of genes ...
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Identification of pediatric septic shock subclasses based on genome wide expression profiling
... with septic shock and most have been based on strategies targeting various components of the immune or inflam- matory system ...of septic shock ...with septic shock. Thus, ...
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Hemodynamic Support in Fluid-refractory Pediatric Septic Shock
... Hemodynamic variables in groups I, II, and III were analyzed after fluid resuscitation and pulmonary artery catheter placement, and every 8 hours for the first 48 hours after fluid resuscitation. Twenty-eight day and ...
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Serum Lactate Level - Predictor of Outcome in Pediatric Septic Shock
... Critical care medicine has remarkably improved in past few decades. Newer antibiotics are being introduced daily. Even then, sepsis is one of the leading causes of death worldwide. Sepsis related deaths are more common ...
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Management of children with sepsis and septic shock: a survey among pediatric intensivists of the Réseau Mère-Enfant de la Francophonie
... for pediatric patients with hypotension refractory to fluid resuscitation (recommendation Grade 2C) and dobutamine in patients with low cardiac output and ele- vated systemic vascular resistance states ...
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A trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal directed fluid sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial
... in pediatric septic shock sur- vival have been attributed to adherence to the first iter- ation of the ACCM septic shock guidelines, and the use of goal-directed targets [21, ...
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... the pediatric age ...in pediatric patients from severe sepsis and septic shock are significantly lower than the rates in adults ...Clinically septic shock is defined as the ...
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Effect of Lactate and Lactate Clearance Condition on the Prognosis of Sepsis in Children
... Septic shock is a common cause of PICU admission and high ...in pediatric septic shock above which mortality increases ...in pediatric patients admitted to ...
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Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis
... Conversely, it has been reported that PMNs isolated from cord blood derived from term and preterm infants fail to form NETs when activated with LPS or inflamma- tory agonists in the interval between 15 and 120 min [61]. ...
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A Study on the Validation of paediatric index of mortality 2 (PIM2) score in the Paediatric Intensive Care Unit of CMC, Vellore
... The PIM Score which was originally developed in Australian PICUs, has been tested and found to have good discriminatory capacity in intensive care units in the U.K and by the same group of authors. Other studies from ...
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Pediatric sepsis and septic shock: definitions and treatment algorithms
... to septic shock, the work of breathing associated with the compensatory respiratory alkalosis can be substantial and contribute, along with fever, to a significant portion of oxygen ...meningococcal ...
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Bench to bedside review: Vasopressin in the management of septic shock
... in septic shock diff ers from previous reviews by providing more information on the physiology and pathophysiology of vasopressin and vasopressin receptors, particularly because of recent interest in more ...
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