Pentose phosphate pathway
ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway
... of pentose phosphate path- way G6PD may be a downstream target of ID1, we won- dered whether ID1 induced-oxaliplatin resistance was mediated by the activation of pentose phosphate ...of ...
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The return of metabolism : biochemistry and physiology of the pentose phosphate pathway
... The pentose phosphate pathway (PPP) is associated with several cancer- and cell-proliferation-related signalling ...p53 pathway can stimulate the PPP by inhibiting phosphofructokinase 1 (PFK1) ...
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Original Article Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis
... KEGG pathway results, we detected pro- teins related to pentose phosphate pathway (PPP), opening a significant key to further research (Table ...
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Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma
... the pentose phosphate pathway (PPP) is an alternative metabolic pathway that, starting from glucose-6-phosphate, generates precursors for nucleotide biosynthesis and NADPH for anabolic ...
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Systematic engineering of pentose phosphate pathway improves Escherichia coli succinate production
... (glycolysis) pathway; PPP, pentose phosphate pathway; 6-P-Glc, glucose-6-phosphate; 6-P-Fru, fructose-6-phosphate; FBP, fructose-1,6-bisphosphate; 1,6-2P-Fru, 1,6-bisphosphate ...
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Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway
... dinucleotide phosphate; NFκB: nuclear factor κB; PPP: pentose phosphate pathway; RT‑PCR: reverse transcription polymerase chain reaction; TNF‑α: tumour necrosis ...
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SUBSTANCES STIMULATING GLUCOSE CATABOLISM BY THE OXIDATIVE REACTIONS OF THE PENTOSE PHOSPHATE PATHWAY IN HUMAN ERYTHROCYTES
... Glucose utilization and lactic acid formation in presence of the stimulating compounds The increased rate of glucose oxidation via the pentose phosphate pathway in the presence of the va[r] ...
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Overcompensation in Response to Herbivory in Arabidopsis thaliana: The Role of Glucose-6-Phosphate Dehydrogenase and the Oxidative Pentose-Phosphate Pathway
... ABSTRACT That some plants benefit from being eaten is counterintuitive, yet there is now considerable evidence demonstrating enhanced fitness following herbivory (i.e., plants can overcompensate). Although there is ...
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The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
... Glucose-6- phosphate dehydrogenase; GAPDH: Glyceraldehyde 3-phosphate dehydro- genase; GFAP: Glial fibrillary acidic protein; GS1/GS2: G6PD siRNAs; GSH: Reduced glutathione; HLA: Human leukocyte antigen; ...
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Enzyme characterisation and kinetic modelling of the pentose phosphate pathway in yeast
... Figure 1: Pictorial representation of the pentose phosphate pathway in Systems Biology Graphical Notation format (SBGN, [Le Nov` ere et al., 2009])), where a circle represents a simple chemical, a ...
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ROLES OF BUFFERING CAPACITY AND PENTOSE PHOSPHATE PATHWAY ACTIVITY IN THE GAS GLAND OF THE GULF TOADFISH OPSANUS BETA
... known as the hexose monophosphate shunt), respectively, contributes to gas exchange through pH and salting-out effects on the oxygen-carrying capacity of the blood. Second, a countercurrent multiplier system (i.e. a rete ...
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A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
... Metabolic reprogramming has emerged as a crucial regulator of immune cell activation, but how systemic metabolism influences immune cell metabolism and function remains to be investigated. To investigate the effect of ...
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Enzyme activity highlights the importance of the oxidative pentose phosphate pathway in lipid accumulation and growth of Phaeodactylum tricornutum under CO2 concentration
... oxidation pentose phosphate pathway is the major resource of cytosolic-generated NADPH, which is cata- lyzed by G6PDH and ...this pathway and produces reductant to meet the cellular needs for ...
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Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiae
... During xylose utilization, up-regulation of gluconeogene- sis and the oxidative pentose phosphate pathway coin- cided with anaerobiosis (Figure 4). On xylose, increased flux in the oxidative PPP is ...
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Pentose phosphate pathway reactions in normal, regenerating, foetal and neoplastic hepatic tissue
... The decrease in total pentose cycle flux but not pathway flux may be the result of either a block in the flow of carbon at a regulatory site in the non-oxidative segment of the cycle and[r] ...
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Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes
... ribose phosphate isomerase (EC: ...ribose phosphate isomerase is transcribed (and supported by the transcription of the genes that code for ribose- phosphate diphosphokinase that peak at 21 HPI), it ...
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THE PENTOSE PHOSPHATE PATHWAY IN HUMAN ERYTHROCYTES
... It is clear from this study that activity of at least three enzymes (G6PD, 6PGD and aldolase) is significantly higher in eryth- rocytes of full-term newborn infants and, to an even great[r] ...
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Co-production of hydrogen and ethanol by pfkA-deficient Escherichia coli with activated pentose-phosphate pathway: reduction of pyruvate accumulation
... EMP pathway might be down-regulated upon over- expression of Zwf and ...PP pathway in partial cyclic mode ...PP pathway is ...PP pathway which is linked to the EMP Table 2 Comparison of ...
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Original Article Proteomic identification of osteosarcoma-derived exosomes and their activation of pentose phosphate pathway
... KEGG pathway analysis, it was clearer to understand the mechanism of exosomal pro- teins in osteosarcoma ...pantose phosphate path- way and regulation of actin cytoskeleton were outlined the special ...
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Inhibition of IRE1 modifies hypoxic regulation of G6PD, GPI, TKT, TALDO1, PGLS and RPIA genes expression in U87 glioma cells
... the pentose phosphate pathway and is also involved in apoptosis as well as angiogenesis [4, 12, ...tose phosphate pathway and NADPH production and promotes cell proliferation through ...
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