Perfused liver
Responses of the perfused liver of neonatal type 2 diabetic rats to gluconeogenic and ammoniogenic substrates
... isolated perfused rat liver for example, the gluconeogenic activity reflects the en- zymatic ...isolated perfused liver from a variety of substrates has been found ...
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Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats
... We have previously reported that unlike acetate, the short- chain fatty acid (SCFA) butyrate enhances the rate of net ATP consumption in isolated perfused liver of rat [1]. However, the contribution of ...
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Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia
... isolated, perfused liver the secretion of glutathione and the glutathione conjugate, dinitrophenyl-glutathione (GS-DNP), from hepatocyte to bile is severely impaired, whereas the sinusoidal secretion from ...
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The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline
... 22. Yan CC, Huxtable RJ. Relationship between glutathione concentration and metabolism of the pyrrolizidine alkaloid, monocrotaline, in the iso- lated, perfused liver. Toxicol Appl Pharmacol. 1995;130(1): ...
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Synthesis and release of Hageman factor (Factor XII) by the isolated perfused rat liver
... isolated perfused rat liver and have compared rates of synthesis in this system with absolute rates of degradation measured in ...livers, perfused for 5 h with a recycling fluid consisting of a ...
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Hepatic origin of cholesteryl oleate in coronary artery atherosclerosis in African green monkeys Enrichment by dietary monounsaturated fat
... isolated, perfused liver, and coronary artery atherosclerosis were examined in African green mon- keys fed diets containing cholesterol and 35% of calories as fat enriched in polyunsaturated, ...
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Effects of Ranolazine on Carbohydrate Metabolism in the Isolated Perfused Rat Liver
... Since ranolazine inhibits oxygen uptake, it seems reasonable to assume that this also represents diminished mitochondrial ATP production. Corroborating this, a diminution of the ATP content was found in the ...
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Bench to bedside review: Microvascular dysfunction in sepsis –hemodynamics, oxygen transport, and nitric oxide
... of perfused liver sinusoids in a rat LPS model of sepsis [47], administration of nitroglycerin to fluid resuscitated septic patients increased sublingual microvascular flow index [33], and the NO donor ...
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STUDIES ON THE MECHANISM OF ETHANOL INDUCED HYPOGLYCEMIA
... Effect of ethanol on the conversion of fructose to glucose and glycogen by the isolated perfused liver* Glucose concentration in milligrams per 100 ml at minutes of perfusion.. Ethanol a[r] ...
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Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis
... isolated perfused liver of normal rats in the presence of high ...isolated perfused rat liver, TUDCA (25 microM) stimulated a sustained increase in the ...
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EPINEPHRINE STIMULATION OF GLUCOSE RELEASE FROM PERFUSED TROUT LIVER: EFFECTS OF ASSAY AND ACCLIMATION TEMPERATURE
... trout cannot be explained in these terms and may reflect an effect of temperature on other processes. In this regard, the dose–response curves for perfused liver reported in Fig. 4 cover a much broader ...
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Regulation of the Conversion of Thyroxine to Triiodothyronine in the Perfused Rat Liver
... the liver. The perfused liver readily extracted T 4 from perfusion medium and converted it to T 3 ...the perfused liver was a function of the size of the liver, the uptake of T 4 ...
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Effect of Serotonin on Glycogen Metabolism in Isolated Rat Liver
... Both the isolated perfused liver and intact animal studies reported here are consistent with the suggestion made by Sjoerdsma that the levels of serotonin present in the portal venous bl[r] ...
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Hepatic microcirculation in the perfused cirrhotic rat liver
... dilution technique. Comparative studies were carried out in noncirrhotic rats and in rats with cirrhosis secondary to chronic exposure to phenobarbital and carbon tetrachloride. The alterations of the sinusoidal bed were ...
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Inhibition of lactate removal by ketone bodies in rat liver Evidence for a quantitatively important role of the plasma membrane lactate transporter in lactate metabolism
... inhibition on D-3-hydroxybutyrate concentration was documented in isolated perfused livers (maximum inhibition of lactate removal, 58% at 14 mM). This phenomenon could be a factor in the development of lactic ...
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Uptake of oleate from albumin solutions by rat liver Failure to detect catalysis of the dissociation of oleate from albumin by an albumin receptor
... the liver cell ...of perfused rat ...the liver can remove unbound material from the sinusoids faster than it can be replenished by dissociation from albumin, resulting in dissociation-limited ...
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LDL receptor–related protein mediates cell surface clustering and hepatic sequestration of chylomicron remnants in LDLR deficient mice
... The role of HSPGs was investigated by using bFGF as a competitor because it binds to HSPGs (7). At a con- centration that should saturate all of the HSPG bind- ing sites, bFGF did not affect remnant removal or clus- ...
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Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver
... livers perfused with the inhibitor appeared disk-shaped in negative stain by electron microscopy with a mean edge thickness of 46 +/- 5 A and a mean diameter of 190 +/- 25 ...
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The regulation of 3 hydroxy 3 methylglutaryl coenzyme A reductase in the isolated perfused rat liver
... In liver removed during the basal period of the diurnal cycle of enzyme activity, a 227 +/- 41% increase in enzyme activity occurred after 3 h of a plasma-free ...by liver perfusion. If livers were removed ...
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Role of chloride and intracellular pH on the activity of the rat hepatocyte organic anion transporter
... Previous studies in cultured rat hepatocytes and isolated perfused rat liver have revealed that initial uptake of these organic anions is markedly reduced upon removal of Cl- from the me[r] ...
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